“glucagon receptor”的搜索结果

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  1. Cenicriviroc Mesylate

    Catalog No. A17028
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    CCR2/5 receptors 抑制剂
    Cenicriviroc(TAK-652,TBR-652)是CCR2和CCR5受体的抑制剂,可使其充当防止病毒进入人细胞的进入抑制剂 了解更多
  2. LY 255283

    Catalog No. A13090
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    BLT2 receptors 拮抗剂
    LY 255283是一种有效的 BLT2 receptors 拮抗剂。 了解更多
  3. Toll-Like Receptor 7 Ligand II

    Catalog No. A12683
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    TLR7 Ligand
    Toll-Like Receptor 7 Ligand II是一种细胞可渗透的羟基腺嘌呤化合物,可作为强效且高度特异性的TLR7(toll样受体7)激动剂,对TLR2/3/5/8/9没有任何可检测的活性。它在刺激体外培养物中产生TLR7依赖性细胞因子方面比R848效力高10倍。 了解更多
  4. Toll-like receptor modulator

    Catalog No. A15264
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    Toll-like receptor modulator是一类在先天免疫系统中起关键作用的蛋白质。是一类在先天免疫系统中起关键作用的蛋白质。 了解更多
  5. IRAK inhibitor 3

    Catalog No. A11457
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    IL-1 receptor-associated kinase (IRAK) kinase modulator
    IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. 了解更多
  6. Fexofenadine HCl

    Catalog No. A11859
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    COX 抑制剂/histamine H1 receptor 激动剂
    Fexofenadine Hydrochloride是一种抗组胺药,可抑制Cox-1,Cox-2,并且是组胺H1受体激动剂,IC50为246 nM。 了解更多
  7. AN-3485

    Catalog No. A20989
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    TLR inhibitor
    AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. 了解更多
  8. AMG 487 S-enantiomer

    Catalog No. A21874
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    CXCR3 antagonist
    AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3. 了解更多
  9. TLR7/8 agonist 1 dihydrochloride

    Catalog No. A21700
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    TLR7/8 agonist
    TLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. 了解更多
  10. SCH 546738

    Catalog No. A21554
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    CXCR3 antagonist
    SCH 546738 is a potent, orally active and non-competitive CXCR3 antagonist, the affinity constant (Ki) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.4 nM in multiple experiments. 了解更多
  11. AMG 487

    Catalog No. A21162
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    CXCR3 antagonist
    AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively. 了解更多
  12. Resatorvid

    Catalog No. A11543
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    TLR4 inhibitor
    Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor and plays pivotal role in various inflammatory diseases. 了解更多
  13. Kynurenic acid sodium

    Catalog No. A20000
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    GPR35/CXCR8 agonist
    Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多
  14. GPR35 agonist 1

    Catalog No. A12462
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    GPR35/CXCR8 agonist
    GPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good druggability. 了解更多
  15. GSK2239633A

    Catalog No. A12175
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    CCR4 antagonist
    GSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist, which inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96????0.11. 了解更多
  16. PF-4878691

    Catalog No. A12233
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    TLR7 agonist
    PF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociate its antiviral and inflammatory activities. 了解更多
  17. MD2-TLR4-IN-1

    Catalog No. A18452
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    MD2-TLR4 inhibitor
    MD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多
  18. CCR4 antagonist 2

    Catalog No. A18471
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    CCR4 拮抗剂
    CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. 了解更多
  19. PS372424

    Catalog No. A19421
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    Human CXCR3 拮抗剂
    PS372424, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity, which inhibits the binding of CXCR3 ligand CXCL10 to CXCR3 receptor with IC50 of 42 nM. 了解更多
  20. GW 766994

    Catalog No. A20039
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    CCR3 拮抗剂
    GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis. 了解更多
  21. Kynurenic acid

    Catalog No. A16581
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    GPR35/CXCR8 拮抗剂
    Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. 了解更多
  22. PF-04634817

    Catalog No. A18659
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    CCR2 /CCR5 dual 拮抗剂
    PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema. 了解更多
  23. USL311

    Catalog No. A18778
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    CXCR4 拮抗剂
    USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. 了解更多
  24. Montelukast

    Catalog No. A17780
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    LTR antagonist
    Montelukast (trade name Singulair) is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. 了解更多
  25. AF 12198

    Catalog No. A17213
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    IL-1 receptor 拮抗剂
    AF 12198是人I型白介素1(IL-1)受体的有效选择性拮抗剂。 了解更多
  26. NSC-23026

    Catalog No. A17151
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    CXCR4 receptor modulator
    NSC-23026是CXCR4受体调节剂。 了解更多
  27. YM-90709

    Catalog No. A15999
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    interleukin-5 receptor 拮抗剂
    YM-90709是白介素5受体拮抗剂。YM-90709抑制IL-5与其周围人嗜酸性粒细胞和丁酸处理的嗜酸性HL-60克隆15细胞的受体结合,IC50值分别为1.0和0.57 microM。 了解更多
  28. MK-571 sodium salt

    Catalog No. A15983
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    CysLT1 receptor 拮抗剂
    MK-571 sodium salt是一种选择性的口服活性CysLT1受体拮抗剂。它阻断LTD4而不是LTC4与人和豚鼠肺膜的结合,Ki值分别为0.22 nM和2.1 nM。 了解更多
  29. MK-571

    Catalog No. A12529
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    CysLT1 receptor 拮抗剂
    MK-571是有效的CysLT1(LTD4)白三烯受体反向激动剂,EC50值为1.3 nM。 了解更多
  30. Reparixin L-lysine salt

    Catalog No. A15219
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    CXCL8 receptor 抑制剂
    Reparixin L-lysine salt是CXCL8受体的抑制剂,也抑制CXCR1和CXCR2的活化,已显示在各种损伤模型中减弱了炎症反应。 了解更多
  31. MK-0679 (Verlukast)

    Catalog No. A11607
    LTD4 receptor 拮抗剂
    MK-0679 (Verlukast)是有效的白三烯D4拮抗剂。 了解更多

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