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21 个项目
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Pifithrin-alpha
Catalog No. A12451 p53 抑制剂Pifithrin-alpha是p53介导的细胞凋亡和p53依赖性基因转录（如细胞周期蛋白G，p21/waf1和mdm2表达）的可逆抑制剂。 了解更多 -
Pifithrin-β
Catalog No. A22006 p53 inhibitorPifithrin-β (PFT β) is a potent p53 inhibitor with an IC50 of 23 μM. 了解更多 -
cis-Pralsetinib
Catalog No. A21586 RET inhibitorcis-Pralsetinib (cis-BLU-667) is a highly potent and selective inhibitor of rearranged during transfection (RET), with IC50s ranging from 0.3 to 0.4 nM for WT RET and four enzyme variants (V804L, V804M, M918T, CCDC6-RET), and with broad, robust and anti-tumor activity against multiple RET-driven solid tumor types. 了解更多 -
Bax-activator-106
Catalog No. A18406 Bax agonistBax-activator-106 is a specific Bax agonist. It acts by promoting Bax-dependent but not Bak-dependent apoptosis. 了解更多 -
PROTAC MDM2 Degrader-4
Catalog No. A18877 MDM2 inhibitorPROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. 了解更多 -
PROTAC MDM2 Degrader-3
Catalog No. A18883 MDM2 degraderPROTAC MDM2 Degrader-3 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-3 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. 了解更多 -
PROTAC MDM2 Degrader-2
Catalog No. A18890 MDM2 inhibitorPROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. 了解更多 -
PROTAC MDM2 Degrader-1
Catalog No. A18897 MDM2 degraderPROTAC MDM2 Degrader-1 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-1 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. 了解更多 -
Nutlin carboxylic acid
Catalog No. A18917 Nutlin 3-based MDM2 ligandNutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. Nutlin carboxylic acid (MDM2 ligand 1) can be connected to the ligand for protein by a linker to form PROTACs. 了解更多 -
(4R,5S)-nutlin carboxylic acid
Catalog No. A18924 Nutlin 3-based MDM2 ligand(4R,5S)-nutlin carboxylic acid (MDM2 ligand 2) is the Nutlin 3-based MDM2 ligand. (4R,5S)-nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTACs. 了解更多 -
RIPK1-IN-3
Catalog No. A19023 RIPK1 inhibitorRIPK1-IN-3 (Example 38), a RIPK1 inhibitor, extracted from patent WO2018148626A1, possesses anti-inflammatory proprieties. 了解更多 -
WEHI-539 hydrochloride
Catalog No. A13327 -
AZ 10417808
Catalog No. A15294 Caspase-3 抑制剂AZ 10417808，caspase-3的选择性非肽抑制剂（Ki = 247 nM）；相对于半胱氨酸蛋白酶1、2、6、7和8（Ki> 10 uM）显示的选择性> 40倍。 了解更多
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- Bcl-2 Family (4)
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- Inhibitor (抑制剂) (15)
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