“AZ 960”的搜索结果

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  1. YO-01027

    Catalog No. A11174
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    γ-secretase 抑制剂
    YO-01027是一种二肽γ-secretase抑制剂,作用于APPL和Notch分裂, 无细胞试验中IC50分别为2.6 nM和2.9 nM,一种抗阿尔茨海默氏病药物。 了解更多
  2. Phenylbutazone (Butazolidin, Butatron)

    Catalog No. A10720
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    COX 抑制剂
    Phenylbutazone (Butazolidin,Butatron)是一种具有研究意义的化合物,它是一种抗炎和抗增殖剂。 了解更多
  3. AZD3839

    Catalog No. A12825
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    BACE1 抑制剂
    AZD3839是人类BACE1的有效选择性抑制剂,Ki为26.1 nM。 了解更多
  4. Tenidap

    Catalog No. A13340
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    COX-1 inhibitor
    Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 ?M and 1.2 ?M for COX-1 and COX-2, respectively. 了解更多
  5. MHP 133

    Catalog No. A20058
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    AChE /M1/M2/5HT4/I2 inhibitor
    MHP 133 is a drug with multiple CNS targets, and inhibits acetylcholinesterase (AChE) with Ki of 69 μM; also active against muscarinic M1 and M2 receptors, serotonin 5HT4 receptors, and imidazole I2 receptors. 了解更多
  6. Lanabecestat

    Catalog No. A12282
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    BACE1 inhibitor
    Lanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. 了解更多
  7. BMS-906024

    Catalog No. A21172
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    gamma secretase inhibitor
    BMS-906024 is an oral and selective gamma secretase inhibitor (GSI) that is a small molecule Notch inhibitor. 了解更多
  8. β-Secretase Inhibitor IV

    Catalog No. A21346
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    BACE-1 inhibitor
    β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. 了解更多
  9. (R)-Rivastigmine D6 tartrate

    Catalog No. A21454
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    cholinesterase inhibitor
    (R)-Rivastigmine D6 (tartrate) is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor. 了解更多
  10. AZD3839 free base

    Catalog No. A21606
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    BACE1 inhibitor
    AZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor. 了解更多
  11. (+)-Phenserine

    Catalog No. A20993
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    cholinesterase noncompetitive inhibitor
    (+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM. 了解更多

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