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CD38 inhibitor 1
Catalog No. A19032 CD38 inhibitorCD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38. 了解更多 -
SEC inhibitor KL-2
Catalog No. A19043 SEC inhibitorSEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. 了解更多 -
BRM/BRG1 ATP Inhibitor-1
Catalog No. A19059 BRM/BRG1 ATP InhibitorBRM/BRG1 ATP Inhibitor-1 is an allosteric dual brahma homolog (BRM)/SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2 (SMARCA2) and brahma related gene 1 (BRG1)/SMARCA4 ATPase activity inhibitor, both IC50s are below 0.005 ?M. 了解更多 -
DNA2 inhibitor C5
Catalog No. A19091 DNA2 inhibitorDNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM. 了解更多 -
Ehp inhibitor 2
Catalog No. A22325 Eph family tyrosine kinase inhibitorEhp inhibitor 2 is a Eph family tyrosine kinase inhibitor. 了解更多 -
FB23 inhibitor
Catalog No. A22571 FB23 is a potent and selective inhibitor of N6-methyladenosine (m6A) demethylase FTO (fat mass and obesity associated protein). 了解更多 -
Raf inhibitor 2
Catalog No. A22641 raf kinase inhibitorRaf inhibitor 2 is a potent raf kinase (IC50<1.0 μM) inhibitor, compound 32, extracted from patent EP1003721B1. Raf inhibitor 2 can be used for cancer research. 了解更多 -
EMT inhibitor-1
Catalog No. A20427 EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. 了解更多 -
Glutaminyl Cyclase Inhibitor 3
Catalog No. A20399 GC inhibitorGlutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer??s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM. 了解更多 -
MAT2A inhibitor 1
Catalog No. A20226 MATA2 inhibitorsMAT2A inhibitor 1 is a methionine adenosyltransferase 2A (MATA2) inhibitor with an IC50 less than l00 nM. 了解更多 -
IK1 inhibitor PA-6
Catalog No. A20216 IK1 inhibitorIK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. 了解更多 -
RIP1 kinase inhibitor 1
Catalog No. A20154 RIP1 kinase inhibitorRIP1 kinase inhibitor 1 (compound 22) is a highly potent, orally available, and brain-penetrating RIP1 kinase inhibitor (pKi=9.04). 了解更多 -
ATX inhibitor 1
Catalog No. A20142 ATX inhibitorATX inhibitor 1 is a potent ATX (IC50=1.23 nM, FS-3 and 2.18 nM, bis-pNPP) inhibitor. 了解更多 -
RIP2 Kinase Inhibitor 3
Catalog No. A20109 RIP2 inhibitorRIP2 Kinase Inhibitor 3 is a highly potent and selective inhibitor of receptor interacting protein-2 (RIP2) Kinase with an IC50 of 1 nM . 了解更多 -
IDH1 Inhibitor 1
Catalog No. A20065 IDH1 inhibitorIDH1 Inhibitor 1 is a potent, orally bioavailable, brain-penetrant and selective mutant IDH1 inhibitor with IC50s of 0.021 μM, 0.045 μM, and 2.52 μM for IDH1R132H, IDH1R132C, and IDH1WT, respectively. Anticancer activity. 了解更多 -
Endothelial lipase inhibitor-1
Catalog No. A20064 endothelial lipase inhibitorEndothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM. 了解更多 -
PI3K/mTOR Inhibitor-1
Catalog No. A20055 PI3K/mTOR inhibitorPI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively. Antitumor activity. 了解更多 -
SOCE inhibitor 1
Catalog No. A20041 SOCE inhibitorSOCE inhibitor 1 is a store-operated calcium entry (SOCE) inhibitor with an IC50 of 4.4 μM. 了解更多 -
Eg5 Inhibitor V, trans-24
Catalog No. A20019 kinesin Eg5 inhibitorEg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer. 了解更多 -
sPLA2-X Inhibitor 31
Catalog No. A20018 sPLA2-X inhibitorsPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively. 了解更多 -
ATM Inhibitor-1
Catalog No. A19931 ATM inhibitorATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibitor, with an IC50 of 0.7 nM. 了解更多 -
ATR inhibitor 1
Catalog No. A19874 ATR inhibitorATR inhibitor 1 is a ATR inhibitor extracted from patent WO2015187451A1, compound I-l, has a Ki value below 1 ?μ. 了解更多 -
AMPD2 inhibitor 1
Catalog No. A19839 AMPD2 inhibitorAMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including drug, tobacco, nicotine and alcohol addictions. 了解更多 -
Glutaminyl Cyclase Inhibitor 2
Catalog No. A19713 glutaminyl cyclase inhibitorGlutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor with an IC50 of 1.23 μM. 了解更多 -
CDK4/6/1 Inhibitor
Catalog No. A19641 CDK4/6 inhibitorCDK4/6/1 Inhibitor is a CDK4/6 inhibitor with IC50s of 3 and 1 nM, respectively. 了解更多 -
Aurora inhibitor 1
Catalog No. A19637 Aurora inhibitorAurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ?? 4 nM and ??13 nM for Aurora A and Aurora B kinase, respectively. 了解更多 -
CHK1 inhibitor
Catalog No. A19623 -
PI3Kγ inhibitor 2
Catalog No. A19606 PI3Kγ inhibitorPI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM. 了解更多 -
ERK1/2 inhibitor 1
Catalog No. A19596 ERK1/2 inhibitorERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively. 了解更多 -
Cyclophilin inhibitor 1
Catalog No. A19577 cyclophilin A inhibitorCyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a. 了解更多 -
BACE-1 inhibitor 1
Catalog No. A19560 BACE-1 inhibitorBACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM. 了解更多 -
ATP synthase inhibitor 1
Catalog No. A19550 F1/FO-ATP synthase complex inhibitorATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels. 了解更多 -
IDH1 Inhibitor 3
Catalog No. A19502 IDH1 inhibitorIDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H. 了解更多 -
GlyT1 Inhibitor 1
Catalog No. A19319 GlyT1 inhibitorGlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1. Antipsychotic activity. 了解更多 -
cyt-PTPε Inhibitor-1
Catalog No. A19276 cyt-PTPε inhibitorcyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity. 了解更多 -
PI3Kdelta inhibitor 1
Catalog No. A19249 PI3Kδ inhibitorPI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM. 了解更多 -
Prolyl Hydroxylase inhibitor 1
Catalog No. A19227 HIF-PHD inhibitorProlyl Hydroxylase inhibitor 1 (Compound 15i) is an orally active hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitor with an IC50 of 62.23 nM. Antianemia agent. 了解更多 -
SGLT inhibitor-1
Catalog No. A19226 SGLT inhibitorSGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively. 了解更多 -
PI3Kγ inhibitor 3
Catalog No. A19206 PI3Kγ inhibitorPI3Kγ inhibitor 3 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively. 了解更多 -
SCD1 inhibitor-1
Catalog No. A19205 SCD1 inhibitorSCD1 inhibitor-1 is a potent and liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitor. 了解更多 -
GSK-3β inhibitor 1
Catalog No. A19186 GSK-3β inhibitorGSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM. 了解更多 -
KRas G12C inhibitor 4
Catalog No. A12972 KRas G12C inhibitorKRas G12C inhibitor 1 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多 -
KRas G12C inhibitor 3
Catalog No. A13018 Kras-G12C inhibitorKRas G12C inhibitor 3 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多 -
KRas G12C inhibitor 2
Catalog No. A13064 Kras-G12C inhibitorKRas G12C inhibitor 2 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多 -
KRas G12C inhibitor 1
Catalog No. A13152 Kras-G12C inhibitor 1KRas G12C inhibitor 1 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多 -
JAK3 covalent inhibitor-1
Catalog No. A18926 JAK3 covalent 抑制剂JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs. 了解更多 -
IKK-2 inhibitor VIII
Catalog No. A11452 -
MI-2 (Menin-MLL inhibitor 2)
Catalog No. A12929 Menin-MLL interaction 抑制剂MI-2 (Menin-MLL inhibitor 2)特异性结合menin并抑制menin与细胞中mll融合蛋白的相互作用。它能有效逆转mll融合蛋白通过下调mll融合蛋白致癌活性下游靶基因的表达来介导白血病转化。mi-2是更好地理解mll介导的白血病发生的新工具，代表了研究menin作为mll融合蛋白致癌辅助因子的作用的新方法。 了解更多
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