“A 300”的搜索结果

产品 301 到 350 共 17506个

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  1. DCLK1-IN-1

    Catalog No. A22319
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    chemical probe
    DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. 了解更多
  2. IM156

    Catalog No. A22320
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    AMPK activator
    IM156 (HL156A), a metformin derivative, is a potent activator of AMPK that increases AMPK phosphorylation. 了解更多
  3. ABTL-0812

    Catalog No. A22321
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    antineoplastic agent
    ABTL-0812 (α-Hydroxylinoleic acid) induces endoplasmic reticulum (ER) stress-mediated autophagy. ABTL-0812 is a first-in-class small molecule with anti-cancer activity. 了解更多
  4. Remibrutinib

    Catalog No. A22322
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    BTK inhibitor
    Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. 了解更多
  5. Benzamidine hydrochloride

    Catalog No. A22323
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    trypsin-like serine proteases inhibitor
    Benzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 ?M, 21 ?M, 20 ?M and 110 ?M for uPA, trypsin, tryptase and factor Xa, respectively. 了解更多
  6. AG1557

    Catalog No. A22324
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    EGFR inhibitor
    AG1557 is a specific and ATP competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, has a pIC50 value of 8.194. 了解更多
  7. Ehp inhibitor 2

    Catalog No. A22325
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    Eph family tyrosine kinase inhibitor
    Ehp inhibitor 2 is a Eph family tyrosine kinase inhibitor. 了解更多
  8. SU5204

    Catalog No. A22326
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    tyrosine kinase inhibitor
    SU5204, a tyrosine kinase inhibitor, has IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively. 了解更多
  9. SYN1143

    Catalog No. A22327
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    dual c-Met/RON inhibitor
    SYN1143 is a potent, selective and orally active dual inhibitor of c-Met/RON, with IC50s of 4 and 9 nM, respectively. 了解更多
  10. RO495

    Catalog No. A22328
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    Non-receptor TYK2 inhibitor
    RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2). 了解更多
  11. S6K-18

    Catalog No. A22329
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    ribosomal protein S6 kinase beta-1 inhibitor
    S6K-18 is a highly selective inhibitor of ribosomal protein S6 kinase beta-1 (S6K1, p70S6K, p70-S6K). 了解更多
  12. BAY-474

    Catalog No. A22330
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    tyrosine-protein kinase c-Met inhibitor
    BAY-474 is a tyrosine-protein kinase c-Met inhibitor. BAY-474 acts as an epigenetics probe. 了解更多
  13. MAZ51

    Catalog No. A22331
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    VEGFR-3 (Flt-4) tyrosine kinase inhibitor
    MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase. 了解更多
  14. BRD6989

    Catalog No. A22332
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    inhibitor of CDK8 and CDK19
    BRD6989 is a selective inhibitor of CDK8 and CDK19. BRD6989 upregulates IL-10. BRD6989 is an analog of the natural product cortistatin A (dCA). 了解更多
  15. IRAK4-IN-4

    Catalog No. A22333
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    IRAK4 inhibitor
    IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. 了解更多
  16. Mobocertinib

    Catalog No. A22334
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    inhibitor of EGFR and HER2 oncogenic mutants
    Mobocertinib (TAK-788) is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity. 了解更多
  17. TH-257

    Catalog No. A22335
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    inhibitor of LIMK1 and LIMK2
    TH-257 is a potent inhibitor of LIMK1 and LIMK2 with IC50 values of 84 nM and 39 nM for LIMK1 and LIMK2, respectively, and it can be used as a chemical probe for LIMK1 and LIMK2. 了解更多
  18. BSJ-03-123

    Catalog No. A22336
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    CDK6-selective small-molecule degrader
    BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC). 了解更多
  19. SR-4835

    Catalog No. A22337
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    dual inhibitor of CDK12/CDK13
    SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). 了解更多
  20. AS2863619

    Catalog No. A22338
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    CDK8 and CDK19 inhibitor
    AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. 了解更多
  21. ASP4132

    Catalog No. A22339
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    AMPK activator
    ASP4132 is an orally active, potent AMPK activator with an EC50 of 18 nM. ASP4132 has anti-cancer activity and makes tumor regression in breast cancer xenograft mouse models. 了解更多
  22. Decursinol angelate

    Catalog No. A22340
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    cytotoxic and protein kinase C (PKC) activating agent
    Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities. 了解更多
  23. 3'-Hydroxypterostilbene

    Catalog No. A22341
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    natural pterostilbene analogue
    3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 ?M for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 了解更多
  24. 7-Nitroindazole

    Catalog No. A22342
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    neuronal nitric oxide synthase inhibitor
    7-Nitroindazole, a heterocyclic compound, acts as a selective inhibitor for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS. 了解更多
  25. Chromium picolinate

    Catalog No. A22343
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    nutritional supplement
    Chromium picolinate is a coordination complex consisting of chromium(III) and picolinic acid. It is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. 了解更多
  26. Dihydrocaffeic acid

    Catalog No. A22344
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    Antioxidant agent
    Dihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity. 了解更多
  27. JNJ-38158471

    Catalog No. A22345
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    VEGFR-2 inhibitor
    JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively. 了解更多
  28. AUDA

    Catalog No. A22346
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    sEH inhibitor
    AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively. AUDA has anti-inflammatory activity. 了解更多
  29. 3-Deazaadenosine hydrochloride

    Catalog No. A22347
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    inhibitor of S-adenosylhomocysteine hydrolase
    3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 ?M; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity. 了解更多
  30. CCG-222740

    Catalog No. A22348
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    MRTF pathway inhibitor
    CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor. CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. 了解更多
  31. 7,4'-Di-O-methylapigenin

    Catalog No. A22349
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    antifungal
    The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines. 了解更多
  32. Pyridoxine

    Catalog No. A22350
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    antioxidant agent
    Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. 了解更多
  33. ADT-OH

    Catalog No. A22351
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    Desmethylanethol trithione
    ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. 了解更多
  34. Nootkatone

    Catalog No. A22352
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    neuroprotective agent
    Nootkatone, a neuroprotective agent from Alpiniae Oxyphyllae Fructus, has antioxidant and anti-inflammatory effects. 了解更多
  35. Timosaponin AIII

    Catalog No. A22353
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    Inhibitor of U46619-induced Rat Platelet Aggregation
    Timosaponin AIII is a potent Inhibitor of U46619-induced Rat Platelet Aggregation, Selectively Inhibiting TxA2-induced Platelet Activation, Preferably Suppressing TP-mediated Activation of Gq, not G12/13, Signaling Pathways. 了解更多
  36. Beta-asarone

    Catalog No. A22354
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    neuroprotection agent
    Beta-Asarone, found in certain plants such as Acorus and Asarum, could pass the blood-brain barrier and exerts neuroprotection effects. 了解更多
  37. Coumarin-3-carboxylic Acid

    Catalog No. A22355
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    antiproliferative agent
    Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line. 了解更多
  38. (2S,3R,4S)-4-Hydroxyisoleucine

    Catalog No. A22356
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    anti-diabetes agent
    (2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound isolated from Trigonella foenum-graecum, with anti-diabetes and anti-diabetic nephropathy activity. 了解更多
  39. Solamargine

    Catalog No. A22357
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    anticancer agent
    Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. 了解更多
  40. Skatole

    Catalog No. A22359
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    bacteriostatic agent
    Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.. 了解更多
  41. 3BDO

    Catalog No. A22360
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    mTOR activator
    3BDO is a new mTOR activator which can also inhibit autophagy. 了解更多
  42. TG-89

    Catalog No. A22361
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    JAK2 inhibitor
    TG-89 is an inhibitor of JAK2 with IC50 of 11.2 μM. 了解更多
  43. BMP signaling agonist sb4

    Catalog No. A22362
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    BMP4 signaling agonist
    BMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. 了解更多
  44. 5-Bromoindole

    Catalog No. A22363
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    inhibitor of glycogen synthase kinase 3
    5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3). 了解更多
  45. Remimazolam

    Catalog No. A22200
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    benzodiazepine derivative drug
    Remimazolam, also known as CNS-7056, is a benzodiazepine derivative drug, developed by PAION, in collaboration with Japanese licensee Ono Pharmaceutical as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures. 了解更多
  46. Pemafibrate

    Catalog No. A22201
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    PPAR alpha agonist
    Pemafibrate, also known as (R)-K 13675, is a PPAR alpha agonist. 了解更多
  47. Avacopan

    Catalog No. A22202
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    selective C5aR antagonist
    Avacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist. 了解更多
  48. SEL24-B489 HCl

    Catalog No. A22203
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    pan-PIM/FLT3 inhibitor
    SEL24-B489 HCl is a potent, dual pan-PIM/FLT3 inhibitor. 了解更多
  49. Perlapine

    Catalog No. A22204
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    hM3Dq DREADD agonist
    Perlapine is a potent and selective hM3Dq DREADD agonist (EC50 = 2.8 nM). This drug exhibits >10,000-fold selectivity for hM3Dq over hM3. 了解更多
  50. Durlobactam sodium

    Catalog No. A13801
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    beta-lactamase inhibitor drug candidate
    Durlobactam, also known as ETX2514, is a beta-lactamase inhibitor drug candidate. 了解更多

产品 301 到 350 共 17506个

每页
页面:
  1. 5
  2. 6
  3. 7
  4. 8
  5. 9

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