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Broflanilide
Catalog No. A19824 Broflanilide is a potential insecticide and metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM. 了解更多 -
Fluxametamide
Catalog No. A19815 Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls. 了解更多 -
Zuranolone
Catalog No. A19805 GABAA receptor agonistZuranolone is a potent GABAA receptor agonist with EC50s of 296 and 163 nM for α1β2γ2 and α4β3δ GABAA receptors, respectively. 了解更多 -
D-Lin-MC3-DMA
Catalog No. A19797 siRNA delivery vehicleD-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle. 了解更多 -
ATRA-hydroxyimino
Catalog No. A19791 ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells. 了解更多 -
5-BrUTP sodium salt
Catalog No. A19789 5-BrUTP sodium salt can be used to label RNA to measure the transcription. 了解更多 -
PROTAC CRABP-II Degrader-1
Catalog No. A19782 CRABP-II degraderPROTAC CRABP-II Degrader-1 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
Calcein Blue
Catalog No. A19780 blue-fluorescent dyeCalcein Blue is a short-term, blue-fluorescent dye for labeling live cells. 了解更多 -
GSK3004774
Catalog No. A19779 CaSR agonistGSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR. 了解更多 -
Retagliptin Phosphate
Catalog No. A19777 DPP-4 inhibitorRetagliptin Phosphate is pharmaceutical composition of DPP-4 inhibitor for treating type-2 diabetes. 了解更多 -
PROTAC CRABP-II Degrader-2
Catalog No. A19773 CRABP-II degraderPROTAC CRABP-II Degrader-2 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
PROTAC CRABP-II Degrader-3
Catalog No. A19764 CRABP-II degraderPROTAC CRABP-II Degrader-3 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
Dabsyl chloride
Catalog No. A19755 amine derivatizing agentDabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. 了解更多 -
Foliglurax
Catalog No. A19753 mGluR4 modulatorFoliglurax (PXT002331) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 79 nM. Antiparkinsonian effect. 了解更多 -
INCB-057643
Catalog No. A19737 -
4-Octyl Itaconate
Catalog No. A19731 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. 了解更多 -
Seclidemstat
Catalog No. A19730 LSD1 inhibitorSeclidemstat (SP-2577) is a potent and orally bioavailable LSD1 inhibitor, with a mean IC50 of 127 nM. 了解更多 -
KDM2A/7A-IN-1
Catalog No. A19724 KDM2A/7A inhibitorKDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of histone lysine demethylases KDM2A/7A, with an IC50 of 0.16?μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases. 了解更多 -
Desisobutyryl-ciclesonide
Catalog No. A19718 Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide. Desisobutyryl-ciclesonide has affinity for the glucocorticoid receptor. 了解更多 -
GPR120 Agonist 1
Catalog No. A19679 GPR120 agonistGPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate. 了解更多 -
Imatinib carbaldehyde
Catalog No. A19670 Imatinib carbaldehyde (CGP-57148B carbaldehyde), the Imatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER. 了解更多 -
4-Hydroxychalcone
Catalog No. A19662 4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 了解更多 -
Bestatin-amido-Me
Catalog No. A19661 Bestatin-amido-Me, the Bestatin-based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER. 了解更多 -
GNF5-amido-Me
Catalog No. A19651 GNF5-amido-Me, the GNF5 (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER. 了解更多 -
MV-1-NH-Me
Catalog No. A19642 MV-1-NH-Me, the MV-1 based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER. 了解更多 -
Melinamide
Catalog No. A19631 cholesterol absorption inhibitorMelinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC50 of 20.9 μM. 了解更多 -
Dasatinib carbaldehyde
Catalog No. A19627 Dasatinib carbaldehyde (BMS-354825 carbaldehyde), the Dasatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER . 了解更多 -
ABT-702 dihydrochloride
Catalog No. A19624 AK inhibitorABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor (IC50=1.7 nM). 了解更多 -
Modecainide
Catalog No. A19620 Modecainide is a major metabolite of Encainide, which is an antiarrhythmic agent. 了解更多 -
SNIPER(ABL)-058
Catalog No. A19616 SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM. 了解更多 -
Heparan Sulfate
Catalog No. A19609 Heparan sulfate, a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix. 了解更多 -
SNIPER(ABL)-024
Catalog No. A19607 SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM. 了解更多 -
PI3Kγ inhibitor 2
Catalog No. A19606 PI3Kγ inhibitorPI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM. 了解更多
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