Histamine Receptors

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  1. A 943931 2HCl

    Catalog No. A13442
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    Histamine H4 receptor 拮抗剂
    943931 2HCl是一种有效的选择性组胺H4受体拮抗剂(人和大鼠受体的pKi值分别为7.15和8.12)。 了解更多
  2. Ebastine

    Catalog No. A14946
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    H1-histamine receptor 拮抗剂
    Ebastine是一种H1抗组胺药,极少引起嗜睡。 了解更多
  3. Cetirizine

    Catalog No. A15041
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    H1-receptor 拮抗剂
    Cetirizine是第二代抗组胺药物,是羟嗪的主要代谢产物,是外消旋的选择性H1受体反向激动剂。 了解更多
  4. Clemizole hydrochloride

    Catalog No. A15047
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    H1 histamine receptor 拮抗剂
    Clemizole hydrochloride是H1组胺受体的拮抗剂,对NS4B RNA结合的IC50值为8 mM。 了解更多
  5. Ebrotidine

    Catalog No. A15075
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    H2-receptor 拮抗剂
    Ebrotidine是一种竞争性的H2受体拮抗剂(Ki = 127.5 nM),具有有效的抗分泌活性和胃保护作用。 了解更多
  6. Zaltidine

    Catalog No. A15285
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    H2-receptor 拮抗剂
    Zaltidine是H2受体拮抗剂,具有抗分泌作用。 了解更多
  7. Bavisant dihydrochloride

    Catalog No. A15015
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    H3 receptor 拮抗剂
    Bavisant dihydrochloride是一种人类H3受体的高选择性,口服活性拮抗剂。 了解更多
  8. Bavisant dihydrochloride hydrate

    Catalog No. A15016
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    H3 receptor 拮抗剂
    Bavisant dihydrochloride hydrate是人类H3受体的高度选择性口服活性拮抗剂。 了解更多
  9. Cyproheptadine hydrochloride

    Catalog No. A16169
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    serotonin/histamine2 拮抗剂
    Cyproheptadine hydrochloride是抗组胺药,是5-羟色胺和组胺的拮抗剂。 了解更多
  10. Alcaftadine

    Catalog No. A16393
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    H1 histamine receptor 拮抗剂
    Alcaftadine是H1受体的高亲和力配体,其pKi(8.5)与其他H1抗组胺药相当。Alcaftadine还是H2和H4受体的拮抗剂,对H3受体没有亲和力。 了解更多
  11. Cyclizine 2HCl

    Catalog No. A16472
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    Histamine H1 receptor 拮抗剂
    Cyclizine 2HCl是具有组胺H1受体拮抗剂活性的哌嗪衍生物。 了解更多
  12. Terfenadine

    Catalog No. A17373
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    H1 histamine receptor antagonist
    Terfenadine ((??)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 and induces p73, Noxa. 了解更多
  13. Levocetirizine Dihydrochloride

    Catalog No. A17440
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    L-isomer of cetirizine and histamine H1 receptor antagonist
    Levocetirizine dihydrochloride is a L-isomer of cetirizine and histamine H1 receptor antagonist. It incrases levels of CD4+ CD25+ T cells and decreases levels of eosinophils, decreasing allergy symptoms. 了解更多
  14. Hydroxyzine pamoate

    Catalog No. A17712
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    Histamine H1 receptor antagonist
    Hydroxyzine pamoate is an histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. 了解更多
  15. Acrivastine

    Catalog No. A17746
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    Histamine 1 receptor antagonist
    Acrivastine (BW825C) is a short acting histamine 1 receptor antagonist for the treatment of allergic rhinitis. 了解更多
  16. Mebhydrolin napadisylate

    Catalog No. A17997
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    histamine H1-receptor antagonist
    Diazoline is a histamine H1-receptor antagonist. 了解更多
  17. Mequitazine

    Catalog No. A18206
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    Histamine H1 antagonist
    Mequitazine is a potent histamine H1 antagonist or antihistamine. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. 了解更多
  18. Ciproxifan maleate

    Catalog No. A11117
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    H3-receptor 拮抗剂
    Ciproxifan maleate是一种有效的选择性H3组胺受体拮抗剂。 了解更多
  19. Orphenadrine citrate

    Catalog No. A11712
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    NMDA receptor 拮抗剂
    Orphenadrine柠檬酸盐是NMDA受体拮抗剂,Ki为6.0μM,还是HERG钾离子通道阻断剂。 了解更多
  20. Lafutidine

    Catalog No. A11714
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    H2 receptor 拮抗剂
    Lafutidine是具有多峰作用机制的第二代H2受体拮抗剂。 了解更多
  21. Asenapine maleate

    Catalog No. A10091
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    H1 拮抗剂
    Asenapine maleate平对多种受体具有高亲和力(pKi),包括5-羟色胺5-HT1A(8.6),5-HT1B(8.4),5-HT2A(10.2),5-HT2B(9.8),5-HT2C(10.5),5 -HT5A(8.8),5-HT6(9.5)和5-HT7(9.9)受体,肾上腺素α1(8.9),α2A(8.9),α2B(9.5)和α2C(8.9)受体,多巴胺D1( 8.9),D2(8.9),D3(9.4)和D4(9.0)受体以及组胺H1(9.0)和H2(8.2)受体。 了解更多
  22. Cimetidine

    Catalog No. A10218
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    H2-receptor 拮抗剂
    Cimetidine是一种抑制胃酸产生的组胺H2受体拮抗剂。 了解更多
  23. Astemizole

    Catalog No. A13899
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    H1-receptor 拮抗剂
    Astemizole是一种有效的抗组胺药物(H1-受体拮抗剂,IC50 = 4 nM),对多巴胺,5-HT和毒蕈碱乙酰胆碱受体具有选择性。该化合物显示出有效的hERG K+通道阻断活性(IC50 = 0.9 nM),在体外多药耐药菌株中具有抗疟疾活性(IC50 = 227-734 nM),并已被用作分子伴侣来纠正折叠缺陷并恢复蛋白质功能 hERG通道的某些突变形式。 了解更多
  24. Promethazine HCl

    Catalog No. A14248
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    Histamine H1 receptor 拮抗剂
    Promethazine HCl是一种有效的组胺H1受体拮抗剂。 了解更多
  25. JNJ7777120

    Catalog No. A12713
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    Histamine 拮抗剂
    JNJ7777120是有效的,选择性的非咪唑histamine H4 receptor拮抗剂。 了解更多
  26. Metiamide

    Catalog No. A13086
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    Histamine H2-receptor 拮抗剂
    Metiamide是从另一种H2拮抗剂burimamide开发出来的组胺H2受体拮抗剂。它是成功开发抗溃疡药物西咪替丁的中间体。 了解更多
  27. Clemizole

    Catalog No. A13073
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    H1 histamine receptor 拮抗剂.
    Clemizole是H1组胺受体拮抗剂。 了解更多
  28. Bepotastine Besilate

    Catalog No. A11340
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    Histamine Receptor 拮抗剂
    Bepotastine Besilate是组胺H1受体激动剂。 了解更多
  29. Chlorcyclizine hydrochloride

    Catalog No. A18025
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    histamine H1 antagonist
    Chlorcyclizine hydrochloride is a histamine H1 antagonist. 了解更多
  30. Toreforant

    Catalog No. A21058
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    histamine H4 receptor (H4R) antagonist
    Toreforant is a potent and selective histamine H4 receptor (H4R) antagonist, with a Ki at the human receptor of 8.4 nM. 了解更多
  31. PF-03654746

    Catalog No. A21429
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    histamine H3 receptor antagonist
    PF-03654746 is a potent and selective histamine H3 receptor antagonist with high brain penetration. 了解更多
  32. PF-03654746 Tosylate

    Catalog No. A21434
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    histamine H3 receptor antagonist
    PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. 了解更多
  33. JNJ-5207852

    Catalog No. A21480
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    histamine H3 receptor antagonist
    JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively. 了解更多
  34. Niperotidine

    Catalog No. A21981
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    histamine H2-receptor antagonist
    Niperotidine is a histamine H2-receptor antagonist. 了解更多
  35. GSK189254A

    Catalog No. A22005
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    histamine H3 receptor antagonist
    GSK189254A (GSK189254) is a novel, potent and selective histamine H3 receptor antagonist with pKi values of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively. 了解更多
  36. Decloxizine

    Catalog No. A20964
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    histamine 1 receptor antagonist
    Decloxizine(UCB-1402; NSC289116) is a histamine 1 receptor antagonist. 了解更多

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