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使用 'Akt' 作为标签的产品

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Triciribine

Catalog No. A13210
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AKT 抑制剂

Triciribine，也称为API-2，可抑制Akt的磷酸化水平和激酶活性。了解更多

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TIC10 isomer

Catalog No. A12720
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AKT 抑制剂?

TIC10通过Foxo3a使Akt和ERK失活，从而诱导TRAIL，具有优越的药物特性：跨血脑屏障传递，优异的稳定性和改善的药代动力学。了解更多

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TIC10

Catalog No. A15903
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Akt 抑制剂?

TIC10通过Foxo3a使Akt和ERK失活，从而诱导TRAIL，具有优越的药物特性：跨血脑屏障传递，优异的稳定性和改善的药代动力学。了解更多

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SC79

Catalog No. A15541
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Akt phosphorylation activator

SC79是AKT激活剂。SC79绑定到模仿PtdIns（3,4,5）P3的结合的Akt的plecktrin同源（PH）域，以诱导Akt的构象变化，从而增强磷酸化和激活。了解更多

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PHT-427

Catalog No. A11032
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AKT 抑制剂

PHT-427是一种新型的Akt/磷脂酰肌醇依赖性蛋白激酶1 pleckstrin同源域抑制剂。了解更多

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Perifosine (NSC-639966)

Catalog No. A10709
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Akt 抑制剂

Perifosine (也为KRX-0401) 充当Akt抑制剂和PI3K抑制剂。了解更多

Product Citations (4)

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- Bjune K, .et al. Inhibitors of AKT kinase increase LDL receptor mRNA expression by two different mechanisms, PLoS One, 2019, Jun 19;14(6):e0218537 PMID: 31216345
- Kyoung-Jae Won, .et al. Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells, Cell Death Dis, 2017, Jan; 8(1): e2554 PMID: 28079882
- Zhipeng Li, .et al. A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation, Oncotarget, 2016, May 31; 7(22): 31892–31906 PMID: 26895469
- Won KJ, .et al. NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription., Apoptosis., 2014, Jan;19(1):179-90 PMID: 24085402
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Miltefosine

Catalog No. A14138
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PI3K/Akt 抑制剂

Miltefosine在癌细胞系A431和HeLa中抑制PI3K/Akt活性，ED50为17.2μM和8.1μM。了解更多

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Methyl Hesperidin

Catalog No. A10581
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Methyl Hesperidin是维生素P组的化合物。了解更多

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Deguelin

Catalog No. A13460
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Deguelin是一种天然产物，具有很强的抗增殖活性。了解更多

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Adooq Bioscience

使用 'Akt' 作为标签的产品

Triciribine

TIC10 isomer

TIC10

SC79

PHT-427

Perifosine (NSC-639966)

Miltefosine

Methyl Hesperidin

Deguelin

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