AMPK

Catalog No.Inhibitor Name AMPK
A13720Dorsomorphin 2HCl
**
A14312WZ4003
****
A11970Dorsomorphin
**
A16281HTH-01-015
***
A11071A 769662
*
A15815ETC-1002

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. PF-06409577

    Catalog No. A16801
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    AMPK 激活剂
    PF-06409577是口服生物可利用的AMPK激活剂,在TR-FRET试验中,对AMPK α1β1γ1的EC50为7 nM。在膜片钳试验(100 uM)中没有检测到对hERG的抑制作用,也不是人类主要细胞色素P450亚型微粒体活性的抑制剂(IC50>100 uM)。 了解更多
  2. MK-3903

    Catalog No. A17063
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    AMPK 激活剂
    MK-3903是有效的选择性AMPK激活剂(EC50 = 8 nM)。口服给药后,MK-3903在小鼠肝脏中表现出强大的靶标参与性,从而改善了小鼠的脂质代谢和胰岛素敏感性。 了解更多
  3. A-769662

    Catalog No. A11071
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    AMPK 激活剂
    A-769662是AMP激活的蛋白激酶(AMPK)的新激活剂。 了解更多
  4. Acadesine (Aicar,NSC 105823)

    Catalog No. A10028
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    AMPK 激活剂
    Acadesine (Aicar,NSC 105823)是肝细胞和脂肪细胞中AMPK的选择性激活剂。 了解更多
  5. ETC-1002

    Catalog No. A15815
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    ACL 抑制剂 and AMPK 激活剂
    ETC-1002是一种新颖的,一流的可以降低LDL-C的小分子;肝AMP激活的蛋白激酶(AMPK)的激活剂;对肝ATP-柠檬酸裂解酶也具有有效的抑制活性(IC50 = 29 uM)。 了解更多
  6. GSK621

    Catalog No. A15896
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    AMPK 激活剂
    GSK621是有效的选择性AMPK激动剂。 了解更多
  7. YLF-466D

    Catalog No. A16284
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    AMPK 激活剂
    YLF-466D是一种变构AMPK激活剂。 了解更多
  8. ex229 (compound 991)

    Catalog No. A16795
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    AMPK 激活剂
    ex229 (compound 991)是一种有效的AMPK活化剂,在活化AMPK方面比A769662的效力高5-10倍。 了解更多
  9. MK8722

    Catalog No. A13392
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    pan-AMPK activator
    MK8722 is a potent and systemic pan-AMPK activator. 了解更多
  10. ZLN024

    Catalog No. A21963
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    AMPK allosteric activator
    ZLN024 is an AMPK allosteric activator. 了解更多

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