Caspase

Catalog No.Inhibitor Name Pan-CaspaseCaspase-1Caspase-2Caspase-3Caspase-4Caspase-5Caspase-6Caspase-7Caspase-8Caspase-9Caspase-10
A10984VX-765 (Belnacasan)
**
***
A12373Z-VAD-FMK
*
A13503Z-DEVD-FMK
A14915Q-VD-OPh hydrate
****
****
***
***
A14919Caspase-3/7 Inhibitor I
****
***
A12611Z-VEID-FMK
A12637Z-VDVAD-FMK
A12697Z-DQMD-FMK
A12800Z-IETD-FMK
A14358Z-LEHD-FMK
A14284Z-FA-FMK
A15300Ivachtin
****
A15392Boc-D-FMK
A14916Z-WEHD-FMK
A15816Ac-DEVD-CHO
***
*
****
**
**
**
***
****
**

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Z-VAD-FMK

    Catalog No. A12373
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    Pan Caspase 抑制剂
    Z-VAD-FMK是一种细胞可渗透、不可逆的泛胱天蛋白酶抑制剂。体外抑制肿瘤细胞caspase加工和凋亡诱导(IC50 = 0.0015 - 5.8 mM)。活跃在体内。 了解更多
  2. Ac-IEPD-AFC

    Catalog No. A15319
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    Fluorogenic caspase substrate
    Ac-LEHD-AFC是caspase-4,caspase-5和caspase-9的荧光底物。 了解更多
  3. VX-765 (Belnacasan)

    Catalog No. A10984
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    Caspase-1/4 抑制剂
    VX-765 (Belnacasan)是一种新型的Caspase-1抑制剂,是一种控制两种细胞因子IL-1b和IL-18生成的酶。 了解更多
  4. Emricasan

    Catalog No. A11394
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    Caspase inhibitor
    Emricasan is a first-in-class caspase inhibitor in clinical trials for the treatment of liver diseases. 了解更多
  5. Z-YVAD-FMK

    Catalog No. A16317
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    Caspase-1 抑制剂
    Z-YVAD-FMK是有效的细胞渗透性和caspase-1不可逆抑制剂。 了解更多
  6. Boc-D-FMK

    Catalog No. A15392
    Caspase 抑制剂
    BOC-D-FMK是Caspase-3的新型抑制剂。 了解更多

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