产品详情
Doramapimod(BIRB 796)是p38 MAPK的小分子抑制剂,在调节促炎细胞因子的产生中起关键作用。
靶点信息
p38α (Cell-free assay) | p38α | |||
0.1 nM(Kd) | 38 nM |
In vitro (25°C) | DMSO | 99 mg/mL (187.61 mM) | |
Water | Insoluble | ||
Ethanol | 99 mg/mL (187.61 mM) | ||
In vivo | 5% DMSO+40%PEG300+5%Tween80??+50%H2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.95 mL | 94.75 mL | 189.5 mL |
0.5 mM | 3.79 mL | 18.95 mL | 37.9 mL |
1 mM | 1.9 mL | 9.48 mL | 18.95 mL |
5 mM | 0.38 mL | 1.9 mL | 3.79 mL |
*The above data is based on the productmolecular weight 527.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10148 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 527.7 |
Formula | C31H37N5O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 285983-48-4 |
Synonyms | BIRB-796,BIRB 796 |
SMILES | CC1=CC=C(C=C1)N2C(=CC(=N2)C(C)(C)C)NC(=O)NC3=CC=C(C4=CC=CC=C43)OCCN5CCOCC5 |
产品资料
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
DBM 1285 dihydrochloride
DBM 1285 dihydrochloride是p38 MAPK抑制剂。在巨噬细胞和体内抑制p38磷酸化和LPS诱导的TNF-α产生。
TRC 051384
TRC 051384,属于取代的2-丙烯-1-酮类,是热休克蛋白70(HSP70)的有效诱导剂。HSP70的诱导是应激细胞的自然…
BMS-582949
BMS-582949是一种双重作用p38激酶抑制剂,非常适合于避免增加细胞p38活化的耐药机制。
Keywords:购买 Doramapimod (BIRB-796) | Doramapimod (BIRB-796) 供应商 | 订购 Doramapimod (BIRB-796) | Doramapimod (BIRB-796) 价格 | Doramapimod (BIRB-796) 生产商 | 订单 Doramapimod (BIRB-796) | Doramapimod (BIRB-796) 代理商 | 购买 285983-48-4| 285983-48-4 供应商 | 订购 285983-48-4 | 285983-48-4 价格 | 285983-48-4 生产商 | 订单 285983-48-4 | 285983-48-4 代理商|buy Doramapimod (BIRB-796) | Doramapimod (BIRB-796) Supplier | purchase Doramapimod (BIRB-796) | Doramapimod (BIRB-796) cost | Doramapimod (BIRB-796) manufacturer | order Doramapimod (BIRB-796) | Doramapimod (BIRB-796) distributor | buy 285983-48-4| 285983-48-4 Supplier | purchase 285983-48-4 | 285983-48-4 cost | 285983-48-4 manufacturer | order 285983-48-4 | 285983-48-4 distributor