产品详情
靶点信息
MEK1 | ||||
3.2 nM |
In vitro | DMSO | 99 mg/mL (196.33 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.83 mL | 99.17 mL | 198.33 mL |
0.5 mM | 3.97 mL | 19.83 mL | 39.67 mL |
1 mM | 1.98 mL | 9.92 mL | 19.83 mL |
5 mM | 0.4 mL | 1.98 mL | 3.97 mL |
*The above data is based on the productmolecular weight 504.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11040 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 504.2 |
Formula | C17H15F2IN4O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1035555-63-5 |
Synonyms | TAK733 |
SMILES | CN1C2=C(C(=C(C1=O)F)NC3=C(C=C(C=C3)I)F)C(=O)N(C=N2)C[C@H](CO)O |
产品标签
Product Questions
Product Questions
GSK1120212 (JTP-74057, Trametinib)
GSK1120212 (JTP-74057,Trametinib)强烈阻止了MEK1和MEK2激酶的活性,而不是其他98种激酶的活性。
RO5126766 (CH5126766)
RO5126766 (CH5126766)是对Raf和MEK丝裂原激活的蛋白激酶(MAPK)具有特异性的蛋白激酶抑制剂,具有潜在的抗肿…
Chlortetracycline Hydrochloride
Chlortetracycline Hydrochloride是一种特殊而有效的钙离子载体抗生素。
MEK inhibitor
MEK inhibitor是一种有效的MEK抑制剂,抗肿瘤剂。
U0126-EtOH
U0126-EtOH是MEK1和MEK2的抑制剂,IC50分别为72 nM和58 nM。
Arctigenin
Arctigenin是抗氧化剂,消炎药,抗增殖药和抗病毒药。它通过抑制IκBα磷酸化和p65核移位来抑制LPS诱导的iNOS…
Cobimetinib (racemate)
Cobimetinib (racemate)是一种有效的,高度选择性的MEK1/2抑制剂。