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搜索结果：“Ligand-gated Ion Channels”

“Ligand-gated Ion Channels”的搜索结果

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ZT-12-037-01

Catalog No. A18395
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ATP-competitive STK19 inhibitor

ZT-12-037-01 is a potent, selective, ATP-competitive STK19 inhibitor. ZT-12-037-01 effectively blocks oncogenic NRAS-driven melanocyte malignant transformation and melanoma growth in vitro and in vivo. 了解更多

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- 最新产品
MRTX1257

Catalog No. A17223
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KRAS-G12C inhibitor

MRTX1257 is a potent, selective, covalent and irreversible inhibitor of KRAS G12C, MRTX1257 inhibited KRAS dependent ERKphosphorylation in the H358cell assay with an IC50= 900 pM. 了解更多

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NSC-23766 HCl

Catalog No. A13975
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Rac GTPase 抑制剂

NSC 23766是Rac特异性GEF TrioN和Tiam 1（IC50 = 50 uM）引起的Rac1激活的细胞可渗透性可逆抑制剂。了解更多

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EHop-016

Catalog No. A12740
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Rac GTPase Inhibitor

EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration. 了解更多

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Kobe0065

Catalog No. A13135
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Ras-Raf interaction 抑制剂

Kobe0065抑制锚定依赖性和非依赖性生长，阻断MEK / ERK活性并诱导H-rasG12V转化的NIH3T3细胞凋亡。了解更多

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NSC 23766

Catalog No. A12546
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Rac1 activation 抑制剂

SC 23766是Rac1-GEF相互作用的选择性抑制剂。通过Rac特异性鸟嘌呤核苷酸交换因子（GEF）TrioN和Tiam1（IC50为50 μM）阻止Rac1激活，而不影响Cdc42或RhoA激活。了解更多

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Zoledronic Acid

Catalog No. A11010
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osteoclastic bone resorption 抑制剂

Zoledronic acid, 破骨细胞抑制剂，通过抑制甲羟戊酸途径诱导破骨细胞凋亡。了解更多

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