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Resminostat

Catalog No. A12556
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HDAC 抑制剂

Resminostat，也称为RAS2410，是一种有效的I和II类组蛋白脱乙酰基酶（HDAC）抑制剂。它结合并抑制HDAC，从而导致高度乙酰化的组蛋白的积累。选择性的抑制HDAC1/3/6，IC50为42.5 nM/50.1 nM/71.8 nM，作用于HDAC8效果弱，IC50为877 nM。了解更多

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Nexturastat A

Catalog No. A14032
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HDAC6 抑制剂

Nexturastat A是一种芳基脲衍生物，可作为组蛋白脱乙酰基酶6（HDAC6）的有效且高度选择性的抑制剂（IC50 = 5.02+/-0.60 nM）。了解更多

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CM-675

Catalog No. A18741
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PDE5/HDAC-1 inhibitor

CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 has potential to treat Alzheimer??s disease. 了解更多

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SIS-17

Catalog No. A18463
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HDAC 11 inhibitor

SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs. 了解更多

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Resminostat hydrochloride

Catalog No. A15220
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HDAC 抑制剂

Resminostat hydrochloride是HDAC1/3/6的有效抑制剂（IC50 = 43-72 nM）；对HDAC8的效力较低，IC50为877 nM。了解更多

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