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最新产品
Ras-IN-3144
Catalog No. A17222 pan-RAS inhibitorRas-IN-3144 is a pan-RAS inhibitor which inhibits RAS signaling pathways in cancer cells and prevents the growth of RAS mutant mouse cancer xenografts. 了解更多 -
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K-Ras-IN-1
Catalog No. A20875 K-Ras inhibitorK-Ras-IN-1 is a K-Ras inhibitor, by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.(the detailed information refer to the reference). 了解更多 -
K-Ras G12C-IN-1
Catalog No. A20937 K-ras G12C inhibitorK-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1. 了解更多 -
K-Ras G12C-IN-2
Catalog No. A20936 covalent K-Ras G12C inhibitorK-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor. 了解更多 -
K-Ras G12C-IN-3
Catalog No. A20931 K-ras G12C inhibitorK-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C. 了解更多 -
K-Ras(G12C) inhibitor 9
Catalog No. A14250 -
Pluripotin (SC-1)
Catalog No. A11225 ERK1/RasGAP 抑制剂Pluripotin (SC-1)的活性是通过联合抑制RasGAP和ERK1介导的，其Kd值分别为98和212 nM。 了解更多 -
K-Ras(G12C) inhibitor 12
Catalog No. A14227 -
K-Ras(G12C) inhibitor 6
Catalog No. A14103 K-Ras(G12C) 抑制剂K-Ras(G12C) inhibitor 6 是致癌性K-Ras（G12C）的不可逆抑制剂，颠覆了天然核苷酸的偏爱性，使GDP优于GTP。 了解更多 -
Pifithrin-alpha
Catalog No. A12451 p53 抑制剂Pifithrin-alpha是p53介导的细胞凋亡和p53依赖性基因转录（如细胞周期蛋白G，p21/waf1和mdm2表达）的可逆抑制剂。 了解更多 -
(Rac)-Antineoplaston A10
Catalog No. A21689 Ras inhibitor(rac)-Antineoplaston A10 is the racemate of Antineoplaston A10. Antineoplaston A10 is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. 了解更多 -
6H05 (TFA)
Catalog No. A21377 K-Ras(G12C) inhibitor6H05 TFA is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). 了解更多 -
APS-2-79 HCl
Catalog No. A16175 KSR/Ras 抑制剂APS-2-79 HCl，稳定KSR（Ras激酶抑制剂）失活状态并拮抗致癌性Ras信号（IC50值为120 nM，对抗KSR2的ATP-生物素探针标记）的小分子。 了解更多 -
Resminostat hydrochloride
Catalog No. A15220 HDAC 抑制剂Resminostat hydrochloride是HDAC1/3/6的有效抑制剂（IC50 = 43-72 nM）；对HDAC8的效力较低，IC50为877 nM。 了解更多 -
6H05 (trifluoroacetate salt)
Catalog No. A14235 -
Lonafarnib (SCH66336)
Catalog No. A12328 FPTase 抑制剂Lonafarnib (SCH66336)是H-ras、K-ras-4B和N-ras的选择性FPTase抑制剂，IC50分别为1.9 nM、5.2 nM和2.8 nM。 了解更多 -
CID-1067700
Catalog No. A21560 pan GTPase inhibitorCID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM. 了解更多 -
GGTI298 Trifluoroacetate
Catalog No. A16560 GGTase I inhibitorGGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM. 了解更多 -
Antineoplaston A10
Catalog No. A17183 -
XRP44X
Catalog No. A16049 -
Balamapimod (MKI-833)
Catalog No. A13119 -
Diazepinomicin
Catalog No. A12891 -
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最新产品
AMG-510 (Sotorasib)
Catalog No. A19021 KRAS G12C covalent inhibitorAMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity. 了解更多 -
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(±)-Huperzine A
Catalog No. A21003 AChE inhibitor(??)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). 了解更多 -
(+)-Phenserine
Catalog No. A20993 cholinesterase noncompetitive inhibitor(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM. 了解更多 -
Ilorasertib
Catalog No. A20982 ATP-competitive multitargeted kinase inhibitorIlorasertib (ABT-348) is a potent and ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A with IC50s of 1 nM, 7 nM, 120 nM, respectively. 了解更多 -
BMS-214662
Catalog No. A20948 farnesyl transferase inhibitorBMS-214662 is a potent and selective farnesyl transferase inhibitor with potent antitumor activity with an IC50 of 1.35 nM. 了解更多 -
Raltegravir potassium
Catalog No. A21403 integrase (IN) inhibitorRaltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. 了解更多 -
Carotegrast
Catalog No. A21997 α4 integrin receptor inhibitorCarotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities. 了解更多 -
Daunorubicin
Catalog No. A21903 topoisomerase II inhibitorDaunorubicin (Daunomycin; RP 13057; Rubidomycin) is a topoisomerase II inhibitor with potent antineoplastic activities. 了解更多 -
Entacapone sodium salt
Catalog No. A21888 COMT inhibitorEntacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. 了解更多
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