“alpha ergocryptine”的搜索结果

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  1. 1alpha, 25-Dihydroxy VD2-D6

    Catalog No. A14969
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    1alpha, 25-Dihydroxy VD2-D6是氘化的维生素D形式。 了解更多
  2. 1alpha, 24, 25-Trihydroxy VD2

    Catalog No. A14968
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    1alpha, 24, 25-Trihydroxy VD2是维生素D类似物。 了解更多
  3. Crisaborole (AN2728)

    Catalog No. A12776
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    PDE4 抑制剂?
    AN2728是一种局部给药的含硼抗炎化合物,可抑制PDE4活性,从而抑制TNFalpha,IL-12,IL-23和其他细胞因子的释放。抑制PDE4的 IC50 值为0.49 μM。 了解更多
  4. Rosiglitazone (BRL-49653)

    Catalog No. A10807
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    PPAR 激动剂
    Rosiglitazone (BRL-49653)是有效的降糖药,也是有效的噻唑烷二酮类胰岛素增敏剂,在大鼠,3T3-L1和人体脂肪细胞中IC50分别为12,4和9 nM。Rosiglitazone是PPAR-gamma的配体,对PPAR-alpha没有结合力。 了解更多
  5. Acarbose

    Catalog No. A10029
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    Anti-Diabetic Agent
    Acarbose是一种肠道alpha-glucosidase抑制剂,用于治疗2型糖尿病以及某些国家的前驱糖尿病。 了解更多
  6. Chiglitazar

    Catalog No. A12701
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    PPARα/γ dual agonist
    Chiglitazar is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively. 了解更多
  7. NXT629

    Catalog No. A18771
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    PPAR-α antagonist
    NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. 了解更多
  8. TAS-116

    Catalog No. A20987
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    HSP90??/HSP90?? inhibitor
    TAS-116 is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor (Kis of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94. TAS-116 demonstrates less ocular toxicity. 了解更多
  9. TOFA

    Catalog No. A12276
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    ACCA inhibitor
    TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ). 了解更多
  10. Terphenyllin

    Catalog No. A18967
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    Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signi?cant α-glucosidase inhibitory activity. 了解更多
  11. Tacalcitol

    Catalog No. A15251
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    Tacalcitol通过调节钙促进正常的骨骼发育。 了解更多
  12. 1alpha-Hydroxy VD4

    Catalog No. A14970
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    1alpha-Hydroxy VD4可有效诱导单核细胞白血病U937,P39/TSU和P31/FUJ细胞分化。 了解更多
  13. Voglibose

    Catalog No. A14945
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    alpha-glucosidase 抑制剂
    Voglibose是缬氨酰胺的N取代衍生物,对α-葡萄糖苷酶具有出色的抑制活性,并且对高血糖症和由高血糖症引起的各种疾病具有抗药性。 了解更多
  14. Celgosivir

    Catalog No. A13118
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    alpha-glucosidase I 抑制剂
    Celgosivir是一种用于潜在治疗HCV感染的α-葡萄糖苷酶I抑制剂。 了解更多
  15. CUDC-305 (DEBIO-0932 )

    Catalog No. A12648
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    HSP90 抑制剂
    CUDC-305 (DEBIO-0932) 是一种新型的热休克蛋白90(HSP90)抑制剂,对HSP90 alpha/beta具有很强的亲和力,对HSP90α和HSP90β的IC50值分别为100和103nM。具有很高的口服生物利用度,并且对多种癌细胞系均具有强大的抗增殖活性(平均IC50为220 nmol/L)。包括许多对护理标准(SOC)药物有抵抗力的非小细胞肺癌(NSCLC)细胞系。 了解更多
  16. Tesaglitazar

    Catalog No. A20891
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    PPAR alpha/gamma agonist
    Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively. 了解更多
  17. GW 6471

    Catalog No. A21934
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    PPARα antagonist
    GW 6471 is a potent PPARα antagonist. 了解更多
  18. Peliglitazar racemate

    Catalog No. A21411
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    dual α/γ PPAR activator
    Peliglitazar racemate is the racemate of Peliglitazar. Peliglitazar is a novel dual α/γ PPAR activator. 了解更多
  19. LXR-623

    Catalog No. A21366
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    LXRα and full LXRβ agonist
    LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively. 了解更多
  20. Indeglitazar

    Catalog No. A21148
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    PPAR agonist
    Indeglitazar is an orally available peroxisome proliferator-activated receptor (PPAR) pan-agonist for all three PPAR subtypes alpha (α), delta (δ) and gamma (γ). 了解更多
  21. LJ570

    Catalog No. A20081
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    PPARα/PPARγ dual agonist
    LJ570 is a PPARα/PPARγ dual agonist with EC50s of 1.05 and 0.12 μM, respectively. 了解更多

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