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5α-Pregnane-3β,6α-diol-20-one
Catalog No. A20118 5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite of progesterone, and it can be produced in starved androgen-responsive prostate cancer cells. 了解更多 -
HIF-2α-IN-1
Catalog No. A20631 HIF-2α inhibitorHIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay. IC50 value: ?? 500 nM Target: HIF-2α. 了解更多 -
PROTAC ERRα ligand 2
Catalog No. A18939 ERRα inverse agonistPROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist with an IC50 of 5.67 nM. PROTAC ERRα ligand 2 (IC50=5.67 nM) displays a ~11-fold improved potency than XCT790 (IC50=61.3 nM). 了解更多 -
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH
Catalog No. A19684 Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a drug for cancer. 了解更多 -
PDGFRα kinase inhibitor 1
Catalog No. A19632 type II PDGFRα kinase inhibitorPDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively. 了解更多 -
IFN alpha-IFNAR-IN-1 hydrochloride
Catalog No. A21667 IFN-α and IFNAR interaction inhibitorIFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). 了解更多 -
PROTAC ERRα Degrader-1
Catalog No. A18910 ERRα DegraderPROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader. 了解更多 -
α-2,3-sialyltransferase-IN-1
Catalog No. A20249 α-2,3-sialyltransferase inhibitorα-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM. 了解更多 -
p38α inhibitor 1
Catalog No. A19182 p38α inhibitorp38α inhibitor 1 is a p38α inhibitor extracted from patent WO 2008076265 A1. 了解更多 -
α-Tocopherol phosphate
Catalog No. A20866 α-Tocopherol phosphate is the compound demonstrating the highest vitamin E activity, which is available both in its natural form as RRR-alpha-tocopherol isolated from plant sources. 了解更多 -
alpha-Amanitin
Catalog No. A14097 alpha-Amanitin is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II. 了解更多 -
PROTAC ERα Degrader-2
Catalog No. A19697 ERα degraderPROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. 了解更多 -
Flutonidine
Catalog No. A22620 alpha2-Adrenergic receptor agonistFlutonidine is an alpha2-Adrenergic receptor agonist. 了解更多 -
STING agonist-1
Catalog No. A12497 human-specific STING agonistSTING agonist-1 (G10) is a novel human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. 了解更多 -
Lexacalcitol
Catalog No. A11482 Lexacalcitol (KH1060) is over 100 times more active than 1alpha,25-dihydroxyvitamin D3 [1alpha,25-(OH)2D3], as judged by in vitro antiproliferative and cell differentiating assays. 了解更多 -
PT2977
Catalog No. A18465 -
K-7174 2HCl
Catalog No. A15446 Cell adhesion 抑制剂K-7174 dihydrochloride是一种新型的细胞粘附抑制剂；抑制由IL-1beta或TNF-alpha诱导的血管细胞粘附分子1（VCAM-1）的表达。 了解更多 -
PI-103 Hydrochloride
Catalog No. A15212 PI3K 抑制剂PI-103 Hydrochloride是对重组PI3K亚型p110alpha（IC50 = 2 nM），p110beta（IC50 = 3 nM），p110delta（IC50 = 3 nM）和p110gamma（IC50 = 15 nM）具有低IC50值的有效抑制剂，对mTOR的效力较低/DNA-PK，IC50为30 nM/23 nM。 了解更多 -
Dexmedetomidine HCl
Catalog No. A11846 alpha2-adrenoceptor 激动剂Dexmedetomidine hydrochloride是美托咪啶的活性异构体，它充当有效的，高度选择性的α2-AR（α2-肾上腺素受体）激动剂。 了解更多 -
PX-478 HCl
Catalog No. A14319 HIF-1alpha 抑制剂PX-478 HCl是HIF-1alpha抑制剂，也是具有潜在抗肿瘤活性小分子。PX-478对已建立的人类肿瘤异种移植物具有出色的活性，可提供具有HIF-1水平正相关的延长的生长延迟的肿瘤消退。PX-478是高度水溶性的分子，具有良好的i.v.，i.p.和p.o.抗肿瘤活性。 了解更多 -
Labetalol HCl
Catalog No. A14239 alpha1/beta adrenergic receptors 拮抗剂Labetalol HCl是选择性α1-肾上腺素能受体和非选择性β-肾上腺素能受体的双重拮抗剂。 了解更多 -
Firategrast (SB 683699)
Catalog No. A12787 α4β1/α4β7 integrin 拮抗剂Firategrast (SB 683699)是一种口服可生物利用的alpha4 beta1/alpha4 beta7整联蛋白拮抗剂，旨在减少淋巴细胞向中枢神经系统（CNS）的运输。 了解更多 -
Crisaborole (AN2728)
Catalog No. A12776 PDE4 抑制剂?AN2728是一种局部给药的含硼抗炎化合物，可抑制PDE4活性，从而抑制TNFalpha，IL-12，IL-23和其他细胞因子的释放。抑制PDE4的 IC50 值为0.49 μM。 了解更多 -
Lidocaine (Alphacaine)
Catalog No. A10530 Lidocaine (Alphacaine)是一种麻醉剂和Ib类抗心律失常药。在失活状态下阻断电压门控钠通道。 了解更多 -
Rosiglitazone (BRL-49653)
Catalog No. A10807 PPAR 激动剂Rosiglitazone (BRL-49653)是有效的降糖药，也是有效的噻唑烷二酮类胰岛素增敏剂，在大鼠，3T3-L1和人体脂肪细胞中IC50分别为12，4和9 nM。Rosiglitazone是PPAR-gamma的配体，对PPAR-alpha没有结合力。 了解更多 -
Dutasteride (Avodart)
Catalog No. A10338 dual 5alpha-reductase 抑制剂Dutasteride (Avodart)是双重的5-a还原酶抑制剂，可抑制睾丸激素转化为二氢睾丸激素（DHT）。 了解更多 -
(Rac)-Benpyrine
Catalog No. A22192 TNF-α inhibitor(Rac)-Benpyrine, a racemate of Benpyrine, is a potent and orally active TNF-α inhibitor. (Rac)-Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research. 了解更多 -
PNU-282987 free base
Catalog No. A22518 PNU 282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ?? 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). 了解更多 -
Ertiprotafib
Catalog No. A20815 PTP1B/IKK-βinhibitor and dual PPARα and PPARβ agonistErtiprotafib is an inhibitor of PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist, with an IC50 of 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ. 了解更多 -
Tiaprost
Catalog No. A19774
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