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22 个项目
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YF-2
Catalog No. A21018 histone acetyltransferase activatorYF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease. 了解更多 -
HDAC-IN-5
Catalog No. A20972 -
Nanatinostat
Catalog No. A21625 HDAC inhibitorNanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM. 了解更多 -
HDACs/mTOR Inhibitor 1
Catalog No. A13462 HDACs/mTOR Inhibitor 1HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies. 了解更多 -
Histone Acetyltransferase Inhibitor II
Catalog No. A12331 cell permeable p300 inhibitorHistone Acetyltransferase Inhibitor II is a potent and cell permeable p300 inhibitor, with an IC50 of 5 ?M; Histone Acetyltransferase Inhibitor II can be used in cancer research. 了解更多 -
Remetinostat
Catalog No. A12149 HDAC inhibitorRemetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma. 了解更多 -
CHDI-390576
Catalog No. A18899 HDAC inhibitorCHDI-390576, a potent, cell permeable and CNS penetrant class IIa histonedeacetylase (HDAC) inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform. 了解更多 -
Ac-Lys-AMC
Catalog No. A18461 fluorescent substrate for HDACAc-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs. 了解更多 -
P300/CBP-IN-3
Catalog No. A18544 p300/CBP histone acetyltransferase inhibitorP300/CBP-IN-3, a p300/CBP histone acetyltransferase inhibitor. 了解更多 -
Splitomicin
Catalog No. A14221 NAD(+)-dependent histone deacetylase Sir2p 抑制剂Splitomicin是一种选择性的NAD(+)-依赖性组蛋白脱乙酰基酶Sir2p抑制剂，IC50为60 uM，在基于细胞的测定中显示出更高的活性。 了解更多 -
CI994 (Tacedinaline)
Catalog No. A11964
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