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mAChR agonist
Oxotremorine M iodide is a potent and non-selective muscarinic acetylcholine receptor (mAChR) agonist.
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mAChR M5 negative allosteric modulator
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration.
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mAChR modulator
Rapacuronium bromide is an allosteric modulator of muscarinic acetylcholine receptor (mAChR).
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muscarinic acetylcholine receptor (mAChR) antagonist
Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
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alpha-1 adrenergic receptors / mAChRs inhibitor
Anisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant.
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Acetylcholine iodide是一种神经递质,存在于神经肌肉接头,植物神经节,副交感神经效应接头,交感神经效应接头的子集以及中枢神经系统的许多部位。
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Oxybutynin (Ditropan)是一种抗胆碱能药物,是一种竞争性的muscarinic acetylcholine receptorM1,M2,和M3拮抗剂,用于缓解尿道和膀胱疾病。
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