“rasgap ras p21”的搜索结果

产品 201 到 250 共 312个

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  1. PF-06424439

    Catalog No. A12608
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    DGAT2 inhibitor
    PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. 了解更多
  2. Ro-15-2041

    Catalog No. A12570
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    platelet phosphodiesterase inhibitor
    Ro 15-2041 is a selective platelet phosphodiesterase inhibitor with antithrombotic properties. 了解更多
  3. ARS-853

    Catalog No. A12542
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    KRAS G12C inhibitor
    ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation. 了解更多
  4. 9-amino-CPT

    Catalog No. A12540
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    Topoisomerase I inhibitor
    9-Aminocamptothecin is a topoisomerase I inhibitor with potent anticancer activity. 了解更多
  5. Pradigastat

    Catalog No. A12475
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    DGAT1 inhibitor
    Pradigastat (LCQ-908) is a diacylglycerol acyltransferase 1 (DGAT1) inhibitor. 了解更多
  6. ML349

    Catalog No. A12301
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    APT-2 inhibitor
    ML349 is a potent and specific acyl protein thioesterase 2 (APT-2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM. 了解更多
  7. SDZ-MKS 492

    Catalog No. A12283
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    cyclic nucleotide phosphodiesterase inhibitor
    SDZ-MKS 492 (MKS 492) is a selective type III isozyme inhibitor of cyclic nucleotide phosphodiesterase, effective in allergic bronchoconstriction and platelet activating factor (PAF) or LTB4-induced inflammatory reactions in animals. 了解更多
  8. SGC2085

    Catalog No. A12272
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    CARM1 inhibitor
    SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 50 nM. 了解更多
  9. T863

    Catalog No. A11386
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    DGAT1 inhibitor
    T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. 了解更多
  10. PF-05180999

    Catalog No. A13006
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    PDE2A inhibitor
    PF-05180999 is a phosphodiesterase 2A (PDE2A) inhibitor, with an IC50 of 1.6 nM. 了解更多
  11. KRas G12C inhibitor 4

    Catalog No. A12972
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    KRas G12C inhibitor
    KRas G12C inhibitor 1 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多
  12. Histone Acetyltransferase Inhibitor II

    Catalog No. A12331
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    cell permeable p300 inhibitor
    Histone Acetyltransferase Inhibitor II is a potent and cell permeable p300 inhibitor, with an IC50 of 5 ?M; Histone Acetyltransferase Inhibitor II can be used in cancer research. 了解更多
  13. WM-8014

    Catalog No. A20006
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    MOZ inhibitor
    WM-8014 is an inhibitor of MOZ, a member of histone acetyltransferases, with an IC50 of 55 nM. 了解更多
  14. Sildenafil citrate

    Catalog No. A10841
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    PDE5 inhibitor
    Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM. 了解更多
  15. O6BTG-octylglucoside

    Catalog No. A11432
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    MGMT inhibitor
    O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. 了解更多
  16. HIV-1 integrase inhibitor

    Catalog No. A11446
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    HIV-1 integrase inhibitor
    HIV-1 integrase inhibitor is uesful for anti-HIV. 了解更多
  17. HIV-1 integrase inhibitor 2

    Catalog No. A11447
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    HIV-1 integrase inhibitor
    HIV-1 integrase inhibitor 2, in the treatment of human immunodeficiency virus (HIV) infection. 了解更多
  18. Mericitabine

    Catalog No. A11539
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    HCV NS5B polymerase inhibitor
    Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication. 了解更多
  19. Diethylcarbamazine citrate

    Catalog No. A16506
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    arachidonic acid metabolism inhibitor
    Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements. 了解更多
  20. Amsacrine hydrochloride

    Catalog No. A17707
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    antineoplastic agent
    Amsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. 了解更多
  21. Pirarubicin Hydrochloride

    Catalog No. A18037
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    topoisomerase II inhibitor
    Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors. 了解更多
  22. Mirodenafil dihydrochloride

    Catalog No. A18047
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    PDE-5 inhibitor
    Mirodenafil dihydrochloride (SK3530 dihydrochloride) is a phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. 了解更多
  23. FTI 276

    Catalog No. A20869
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    PFT inhibitor
    FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human. 了解更多
  24. D77

    Catalog No. A20905
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    anti-HIV-1 inhibitor
    D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. 了解更多
  25. Galidesivir hydrochloride

    Catalog No. A20930
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    RdRp inhibitor
    Galidesivir hydrochloride (BCX 4430 hydrochloride) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor; demonstrated broad-spectrum activity in multiple viruses and a favorable preliminary preclinical safety profile. 了解更多
  26. Teglicar

    Catalog No. A21061
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    L-CPT1 inhibitor
    Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). 了解更多
  27. Gepotidacin

    Catalog No. A21086
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    topoisomerase II inhibitor
    Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. 了解更多
  28. LY 222306

    Catalog No. A21133
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    GARFT inhibitor
    LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM. 了解更多
  29. Namitecan

    Catalog No. A21146
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    topoisomerase I inhibitor
    Namitecan is a potent topoisomerase I inhibitor, with antitumor property. 了解更多
  30. Karenitecin

    Catalog No. A21156
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    topoisomerase I inhibitor
    Karenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity. 了解更多
  31. BRD9539

    Catalog No. A21201
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    EHMT2 inhibitor
    BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 ?M. 了解更多
  32. Ezatiostat hydrochloride

    Catalog No. A21222
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    glutathione analog inhibitor
    Ezatiostat hydrochloride (TER199;TLK199 hydrochloride) is a glutathione analog inhibitor of glutathione S-transferase P1-1 (GSTP1-1). 了解更多
  33. Edotecarin

    Catalog No. A21233
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    Topoisomerase I inhibitor
    Edotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM. 了解更多
  34. Letermovir

    Catalog No. A21248
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    CMV inhibitor
    Letermovir is a novel inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. 了解更多
  35. Mirodenafil

    Catalog No. A21260
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    PDE-5 inhibitor
    Mirodenafil(SK3530) is a phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. 了解更多
  36. Potassium oxonate

    Catalog No. A21302
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    uricase inhibitor
    Potassium oxonate is an inhibitor of uricase, inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and intact cells in vitro. 了解更多
  37. PF-06424439 methanesulfonate

    Catalog No. A21343
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    DGAT2 inhibitor
    PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. 了解更多
  38. Rasagiline 13C3 mesylate racemic

    Catalog No. A21350
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    Monoamine oxidase inhibitor
    Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. 了解更多
  39. ALS-8112

    Catalog No. A21374
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    RSV polymerase inhibitor
    ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM. 了解更多
  40. Filibuvir

    Catalog No. A21392
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    non-nucleoside inhibitor
    Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the ??Thumb 2?? pocket of NS5B. 了解更多
  41. Saterinone hydrochloride

    Catalog No. A21402
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    PDE3 inhibitor
    Saterinone hydrochloride is a phosphodiesterase III (PDE III) inhibitor. 了解更多
  42. CVT-12012

    Catalog No. A21447
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    SCD inhibitor
    CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively. 了解更多
  43. (R)-Rivastigmine D6 tartrate

    Catalog No. A21454
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    cholinesterase inhibitor
    (R)-Rivastigmine D6 (tartrate) is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor. 了解更多
  44. VXc-?486

    Catalog No. A21471
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    gyrase B inhibitor
    VXc-486 is a gyrase B inhibitor, with bactericidal activity. 了解更多
  45. AMG 579

    Catalog No. A21478
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    PDE10A inhibitor
    AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. 了解更多
  46. Beclabuvir

    Catalog No. A21511
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    HCV NS5B RNA-dependent RNA polymerase inhibitor
    Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. 了解更多
  47. Exatecan Mesylate

    Catalog No. A21515
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    DNA topoisomerase I inhibitor
    Exatecan Mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. 了解更多
  48. Dxd

    Catalog No. A21517
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    DNA topoisomerase I inhibitor
    Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a). 了解更多
  49. GSK3368715 dihydrochloride

    Catalog No. A21733
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    PRMT inhibitor
    GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). 了解更多
  50. BAY 73-6691 racemate

    Catalog No. A21745
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    PDE9 inhibitor
    BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1. 了解更多

产品 201 到 250 共 312个

每页
页面:
  1. 3
  2. 4
  3. 5
  4. 6
  5. 7

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