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￥ 0.00 “Ligand-gated Ion Channel”的搜索结果
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KCTD5 Human
Catalog No. AP0481 Potassium Channel Tetramerisation Domain Containing 5 Human Recombinant 了解更多 -
KCTD11 Human
Catalog No. AP0581 Potassium Channel Tetramerisation Domain Containing 11 Human Recombinant 了解更多 -
KCTD4 Human
Catalog No. AP0992 Potassium Channel Tetramerisation Domain Containing 4 Human Recombinant 了解更多 -
SCN3B Human, Sf9
Catalog No. AP1630 Sodium Channel Voltage-Gated, Type III Beta Human Recombinant, Sf9 了解更多 -
KCTD15 Antibody
Catalog No. AP2975 Potassium channel tetramerisation domain containing 15, Mouse Anti Human 了解更多 -
KCTD15 PAT2B11AT Antibody
Catalog No. AP3220 Potassium channel tetramerisation domain containing 15, Clone PAT2B11AT, Mouse Anti Human 了解更多 -
NPPB
Catalog No. A16981 -
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最新产品
SKA-31
Catalog No. A17117 -
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Terfenadine
Catalog No. A17373 H1 histamine receptor antagonistTerfenadine ((??)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 and induces p73, Noxa. 了解更多 -
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最新产品
SAR-7334 HCl
Catalog No. A17237 TRPC6 inhibitorSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected. 了解更多 -
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PF-06305591
Catalog No. A18748 NaV1.8 blockerPF-06305591 is a potent and highly selective voltage gated sodium channel NaV1.8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile. 了解更多 -
ML418
Catalog No. A18426 Kir7.1 potassium channels blockerML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. 了解更多 -
Dronedarone Hydrochloride
Catalog No. A11389 K+/Na+/Ca+ Channel BlockerDronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents. 了解更多 -
Almitrine mesylate
Catalog No. A18020 Peripheral chemoreceptor agonistAlmitrine mesylate, a peripheral chemoreceptor agonist, inhibits selectively the Ca2+-dependent K+ channel. 了解更多 -
Cav 2.2 blocker 1
Catalog No. A19065 Cav 2.2 blockerCav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM. 了解更多 -
NaV1.7 inhibitor-1
Catalog No. A18933 NaV 1.7 inhibitorNaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5. 了解更多 -
TRPC6-IN-1
Catalog No. A12309 TRPC6 inhibitorTRPC6-IN-1 is a Transient Receptor Potential Canonical 6 Channel (TRPC6) inhibitor, with an EC50 of 4.66 μM. 了解更多 -
Amiodarone hydrochloride
Catalog No. A11798 Amiodarone hydrochloride is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. 了解更多 -
Nicainoprol
Catalog No. A12269 Nicainoprol is a fast-sodium-channel blocking drug, which is a potent antiarrhythmic agent. 了解更多 -
Clofilium tosylate
Catalog No. A12267 Clofilium tosylate, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. Antiarrhythmic agent. 了解更多 -
Norverapamil hydrochloride
Catalog No. A12249 P-gp inhibitorNorverapamil hydrochloride ((??)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. 了解更多 -
Pinacidil monohydrate
Catalog No. A17380 Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator. 了解更多 -
Levcromakalim
Catalog No. A21247 KATP activatorLevcromakalim ((-)-Cromakalim) is an ATP-sensitive K+ channel (KATP) activator. 了解更多 -
Mirogabalin
Catalog No. A21626 Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. 了解更多 -
RPR-260243
Catalog No. A20977 HERG activatorRPR-260243 is a novel activator of HERG; modifies HERG currents inhibited by dofetilide (IC50 = 58 nM); little effect on HERG current amplitude and no significant effects on steady-state activation parameters or on channel inactivation processes. 了解更多 -
Amiodarone
Catalog No. A21278 Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM. 了解更多 -
(-)-Menthol
Catalog No. A15621 (-)-Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i. Antitumor activity. 了解更多 -
BMS-191011
Catalog No. A19972 BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models. 了解更多 -
VU591 hydrochloride
Catalog No. A20009 ROMK inhibitorVU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. 了解更多 -
XE 991 dihydrochloride
Catalog No. A20032 Kv7 (KCNQ) channels blockerXE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 ?M, 0.71 ?M, 0.6 μM, and 0.98 ?M, respectively. 了解更多 -
Almokalant
Catalog No. A20144 Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current. 了解更多 -
Antihistamine-1
Catalog No. A20515 Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively. 了解更多 -
CRAC intermediate 1
Catalog No. A20601 CRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors, detailed information can be found in Patent WO 2010122089 A1, intermediate 9. 了解更多
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