Andrographolide是具有抗癌和免疫调节活性的令人感兴趣的药效团，因此具有被开发为癌症治疗剂的潜力。 了解更多

2-Methoxyestradiol是一种凋亡，抗增殖和抗血管生成剂。通过两种途径诱导p53诱导的细胞凋亡：p38和NF-κB的激活；和激活JNK和AP-1导致Bcl-2磷酸化。 了解更多

Adarotene (ST1926)Adarotene 是一种有效的 apoptosis 诱导剂，通过产生 DNA 损伤，来阻止人类肿瘤细胞的增殖。 了解更多

Apoptosis Activator 2 强烈诱导caspase-3激活，PARP裂解和DNA片段化，导致细胞破坏（依赖Apaf-1），IC50为约4μM，对HMEC，PREC或MCF-10A细胞无效。 了解更多

LY573636 (Tasisulam)是一种有效的抗肿瘤剂，在体外和体内引起多种人实体瘤的生长停滞和凋亡。LY573636诱导的凋亡通过线粒体靶向机制发生。 了解更多

同型harringtonine是一种头孢他辛生物碱，可抑制肝核糖体中二苯丙氨酸和乙酰苯丙氨酰嘌呤霉素的形成。 了解更多

Episilvestrol是Silvestrol的衍生物，它可以通过线粒体/凋亡途径在LNCaP细胞中诱导凋亡，而不会激活执行子caspase-3或-7。5'myc-UTR-LUC抑制剂（IC50 = 0.8 nM）。 了解更多

SMIP004是人类前列腺癌细胞的癌细胞选择性凋亡的新型诱导剂。" 了解更多

2,3-DCPE hydrochloride显示抗癌剂特性并诱导ERK活化。 了解更多

CHM 1是一种有效的体外人肝癌选择性选择性抗肿瘤药。 了解更多

iMAC2抑制线粒体细胞凋亡诱导的通道(MAC)（IC50 = 28 nM）。 了解更多

Ac-DEVD-CHO是醛肽和CPP32/Apopain抑制剂。 了解更多

Apoptosis Inhibitor (M50054)是细胞可渗透的凋亡诱导抑制剂。 了解更多

A unique collection of 157 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc.

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Cytokine Induced Apoptosis Inhibitor 1 Human Recombinant 了解更多

THAP Domain Containing, Apoptosis Associated Protein 1 Human Recombinant 了解更多

TGFB1-Induced Anti-Apoptotic Factor 1 Human Recombinant 了解更多

Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 Human Recombinant 了解更多

Nuclear Apoptosis Inducing Factor 1 Human Recombinant 了解更多

THAP Domain Containing, Apoptosis Associated Protein 7 Human Recombinant 了解更多

THAP Domain Containing, Apoptosis Associated Protein 11 Human Recombinant 了解更多

THAP Domain Containing, Apoptosis Associated Protein 3 Human Recombinant 了解更多

Tumor Protein P53 Regulated Apoptosis Inducing Protein 1 Human Recombinant 了解更多

Fas Apoptotic Inhibitory Molecule Human Recombinant 了解更多

Modulator Of Apoptosis 1 Human Recombinant 了解更多

TP53 Regulated Inhibitor Of Apoptosis 1 Human Recombinant 了解更多

CASP8 and FADD-Like Apoptosis Regulator Human Recombinant 了解更多

CASP8 and FADD-like apoptosis regulator, Mouse Anti Human 了解更多

Apoptosis-Inducing Factor Mitochondrion-Associated 1, Mouse Anti Human 了解更多

Caspase 3 Apoptosis-Related Cysteine Peptidase Human Recombinant 了解更多

Caspase 2 Apoptosis-Related Cysteine Peptidase Human Recombinant 了解更多

TNF-Related Apoptosis Inducing Ligand/Apo2L Mouse Recombinant 了解更多

Terfenadine ((??)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 and induces p73, Noxa. 了解更多

Iincyclinide, also known as CMT-3 and COL-3, is a MMP inhibitor and a chemically-modified tetracycline with potential antineoplastic activity. Incyclinide inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent also causes mitochondrial depolarization in tumor cells and induces both cellular apoptosis and tissue necrosis. 了解更多

NUN82647, also known as QBS or 2-Amino-N-quinolin-8-yl-benzenesulfonamide, is an Inhibitor of cell cycle at G2 phase; apoptosis inducer. 了解更多

Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells. 了解更多

Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic drugs. 了解更多

dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1. 了解更多

Mcl1-IN-8 (Comp8) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells. 了解更多

Mcl1-IN-1 is a potent and selective inhibitor of the apoptosis regulating proteins Mcl-1. 了解更多

WEHI-9625 is a tricyclic sulfone small molecule inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK, but is completely inactive against both human BAK and the closely related apoptosis effector BAX. 了解更多

Lanatoside C is an anticancer agent, acting through protein kinase C-delta (PKCdelta) to cause apoptosis of human hepatocellular carcinoma cells. 了解更多

Sodium Dichloroacetate, also known as CPC-211; DCA; X-11S, is a Pyruvate dehydrogenase kinase inhibitor potentially for the treatment of myocardia ischemia, ischemic. Sodium dichloroacetate also exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3. Sodium dichloroacetate (DCA) reduces apoptosis in colorectal tumor hypoxia. 了解更多

Sodium succinate dibasic is an inhibitor of multiple receptor tyrosine kinases. Sodium succinate dibasic is known to be a potent inhibitor of Met, Flt-1 (VEGFR1), Flk-1 (VEGFR2), Flt-3 (VEGFR3), Ron, and Tie-2. Sodium succinate dibasic has been observed to inhibit Met (c-Met)-driven tumor cell and non-c-Met driven tumor cell (HCT116 and MDA-MB-231) proliferation. This product has also been observed to effectively inhibit c-Met phosphorylation and its downstream signaling pathways in serum starved MKN45 cells, as well as inducing apoptosis in these cells. 了解更多

Deracoxib is an NSAID and COX-2 inhibitor used to treat osteoarthritis. It induces cell cycle arrest and apoptosis in mammary tumor cells, decreases platelet aggregation, and lowers inflammatory responses. 了解更多

Peretinoin, also known as NIK-333 , orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities. Peretinoin binds to and activates nuclear retinoic acid receptors (RAR), which in turn recruit coactivator proteins and promote, with other transcriptional complexes, the transcription of target genes. As a result, this agent may modulate the expression of genes involved in the regulation of cell proliferation, cell differentiation, and apoptosis of both normal and tumor cells. 了解更多

TVB-3166 is an orally-available, reversible, potent, and selective FASN inhibitor, inducing apoptosis, inhibiting anchorage-independent cell growth under lipid-rich conditions, and inhibiting in-vivo xenograft tumor growth. 了解更多

AOH1160 is a potent, first-in-class, orally available small molecule proliferating cell nuclear antigen (PCNA) inhibitor, interferes with DNA replication, blocks homologous recombination-mediated DNA repair, causes cell-cycle arrest and induces apoptosis. 了解更多

CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells. 了解更多