“alpha ergocryptine”的搜索结果

产品 151 到 200 共 642个

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  1. BOC-D-FMK

    Catalog No. A11356
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    caspase inhibitor
    Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 ?M. 了解更多
  2. Kynurenic acid sodium

    Catalog No. A20000
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    GPR35/CXCR8 agonist
    Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多
  3. Tyrosine kinase-IN-1

    Catalog No. A12486
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    multi-targeted tyrosine kinase inhibitor
    Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively. 了解更多
  4. GLPG0187

    Catalog No. A13423
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    Integrin receptor antagonist
    GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM. 了解更多
  5. MDRTB-IN-1

    Catalog No. A13440
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    MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv with a MIC90 value of 10.5 μM. 了解更多
  6. Elacestrant

    Catalog No. A12244
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    Estrogen receptor degrader
    Elacestrant (RAD1901) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. 了解更多
  7. TOFA

    Catalog No. A12276
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    ACCA inhibitor
    TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ). 了解更多
  8. Apratastat

    Catalog No. A13330
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    dual TACE/MMPs inhibitor
    Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) . 了解更多
  9. Parsaclisib

    Catalog No. A13561
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    PI3Kδ inhibitor
    Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases. 了解更多
  10. Dactolisib Tosylate

    Catalog No. A11327
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    dual PI3K and mTOR kinase inhibitor
    Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2. 了解更多
  11. TES-1025

    Catalog No. A13284
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    ACMSD inhibitor
    TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13??3 nM. 了解更多
  12. DCVC

    Catalog No. A12447
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    DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro. 了解更多
  13. Argininic acid

    Catalog No. A18854
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    Argininic acid is an α-amino acid that is used in the biosynthesis of proteins. 了解更多
  14. Terphenyllin

    Catalog No. A18967
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    Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has signi?cant α-glucosidase inhibitory activity. 了解更多
  15. Eicosatetraynoic acid

    Catalog No. A19008
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    COX/LOX inhibitor
    Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively). Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 ?M?? 了解更多
  16. LG-100064

    Catalog No. A19413
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    RXR agonist
    LG-100064 is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ; LG-100064 can be used in the research of cancer. 了解更多
  17. LXS196

    Catalog No. A19419
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    PKC inhibitor
    LXS196 is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. It can be used for the treatment of uveal melanoma. 了解更多
  18. UM-164

    Catalog No. A19895
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    c-Src inhibitor
    UM-164 (DAS-DFGO-II) is a highly potent inhibitor of c-Src with a Kd of 2.7 nM. UM-164 also potently inhibits p38α and p38β. 了解更多
  19. NRA-0160

    Catalog No. A20128
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    Dopamine D4 receptor antagonist
    NRA-0160 is a selective dopamine D4 receptor antagonist, with a Ki value of 0.48 nM and with negligible affinity for dopamine D2 receptor (Ki: >10000 nM), D3 receptor (Ki: 39 nM), rat 5-HT2A receptor (Ki: 180 nM) and rat α1 adrenoceptor (Ki: 237 nM). 了解更多
  20. D-Melibiose

    Catalog No. A17414
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    D-Melibiose is a disaccharide which is composed of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage. 了解更多
  21. Kynurenic acid

    Catalog No. A16581
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    GPR35/CXCR8 拮抗剂
    Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8. 了解更多
  22. DW14800

    Catalog No. A18491
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    PRMT5 inhibitor
    DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity. 了解更多
  23. SJFδ

    Catalog No. A18599
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    10-atom linker PROTAC
    SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38δ with a DC50 of 46.17?nM, but does not degrade p38α, p38β, or p38γ. 了解更多
  24. BJE6-106

    Catalog No. A18627
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    PKCδ inhibitor
    BJE6-106 (B106) is a potent, selective 3rd generation PKCδ inhibitor with an IC50 of 0.05 μM and targets selectivity over classical PKC isozyme PKCα (IC50=50 μM). 了解更多
  25. AS2717638

    Catalog No. A18630
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    LPA5 antagonist
    AS2717638 is an oral active and selective lysophosphatidic acid receptor 5 (LPA5) antagonist, with an IC50 of 38 nM for hLPA5. AS2717638 also significantly improves PGE2-, PGF2α-, and AMPA-induced allodynia. 了解更多
  26. BMS-193885

    Catalog No. A18740
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    neuropeptide Y1 receptor antagonist
    BMS-193885 is a potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over ??1, α1, Y2, Y4 and Y5 receptors respectively. 了解更多
  27. SMAP-2 (DT-1154)

    Catalog No. A18776
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    PP2A activator
    SMAP-2 (DT-1154) is an orally bioavailable phosphatase 2A (PP2A) activator which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. 了解更多
  28. KT203

    Catalog No. A18783
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    ABHD6 inhibitor
    KT203 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.31 nM in Neuro2A cells. 了解更多
  29. KT182

    Catalog No. A18791
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    ABHD6 inhibitor
    KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells. 了解更多
  30. MC180295

    Catalog No. A18892
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    CDK9 inhibitor
    MC180295 is a highly selective CDK9 inhibitor (IC50 = 5 nM). MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect. 了解更多
  31. Santonin

    Catalog No. A18187
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    Santonin is an Anthelmintic isolated from the dried unexpanded flower heads of Artemisia maritima and other species of Artemisia found principally in Russian and Chinese Turkestan and the Southern Ural region. 了解更多
  32. L-Citrulline

    Catalog No. A17922
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    α-amino acid
    L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway. 了解更多
  33. Glucagon HCl

    Catalog No. A17906
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    Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It works to raise the concentration of glucose in the bloodstream. Its effect is opposite that of insulin, which lowers the glucose. 了解更多
  34. Ergoloid Mesylates

    Catalog No. A17883
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    Ergoloid Mesylates, also known as dihydroergotoxine mesylate, is a mixture of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine). Ergoloid mesylates is used as a treatment for dementia and Alzheimer disease. 了解更多
  35. Sulbenicillin Sodium

    Catalog No. A17598
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    Antibiotic
    Sulbenicillin disodium is a semisynthetic penicillin-type antibiotic. 了解更多
  36. Actarit

    Catalog No. A17497
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    Antiarthritic
    Actarit is a drug that has been shown to suppress disease activity of rheumatoid arthritis (RA). Actarit reduces spontaneous tumor necrosis factor-alpha and interleukin 1beta secretion by primary synovial cells of patients with RA. 了解更多
  37. Vitamin K1

    Catalog No. A17408
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    Vitamin K1 a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. 了解更多
  38. Pimozide

    Catalog No. A17375
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    Dopamine receptor antagonist
    Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5. 了解更多
  39. Amitraz

    Catalog No. A17266
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    Amitraz, also known as Mitaban and Taktic, is an alpha-adrenergic receptor agonist and MAO inhibitor used as an insecticide in prevention of flea and tick infections. It prevents prostaglandin synthesis and may inhibit beta-cell insulin release. 了解更多
  40. Abiraterone metabolite 1

    Catalog No. A16992
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    Abiraterone metabolite 1是abiraterone的5β还原代谢产物。类固醇药物abiraterone可抑制CYP17A1,阻断雄激素的合成并延长前列腺癌的生存期。 了解更多
  41. Obtustatin

    Catalog No. A17185
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    α1β1 抑制剂
    Obtustatin是高度有效的整联蛋白α1β1抑制剂(α1β1与IV型胶原的结合的IC 50 = 0.8 nM)。与α2β1,βIIbβ3,αvβ3,α4β1,β5β6,α9β1和α4β7相比,α1β1具有选择性。在鸡绒膜尿囊炎模型中抑制FGF2刺激的血管生成。在Lewis肺癌的协同小鼠模型中显示抗肿瘤功效;阻止人黑素瘤在裸鼠中的生长。 了解更多
  42. BTT-3033

    Catalog No. A17200
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    α2β1 integrin 抑制剂
    BTT-3033是α2β1整联蛋白抑制剂。 了解更多
  43. GSK4112

    Catalog No. A17135
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    Rev-Erbα 激动剂
    GSK4112是选择性的Rev-erbα激动剂,EC50值为250 nM。GSK4112是小分子化学探针, 用于核血红素受体REV-erbα的细胞生物学研究。 了解更多
  44. Urapidil

    Catalog No. A17074
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    α1 adrenoreceptor 拮抗剂
    Urapidil是一种α1肾上腺素受体拮抗剂和5-HT1A受体激动剂。 了解更多
  45. NS 1738

    Catalog No. A17079
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    α7 Positive Modulator
    NS 1738是α7阳性变构调节剂。在卵母细胞实验中,正调节 α7nAChR,EC50 为 3.4 μM。 了解更多
  46. RS 17053 HCl

    Catalog No. A16885
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    α1A 拮抗剂
    RS 17053 HCl是α1A受体拮抗剂,对α1A受体具有很高的亲和力(pKi和pA2估计为9.1-9.9),选择性比α1B和α1D亚型高30-100倍(pKi和pA2估计为7.7- 7.8)。 了解更多
  47. SR 18292

    Catalog No. A16914
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    PGC-1α 抑制剂
    SR 18292是PGC-1α抑制剂。在T2D的饮食和遗传小鼠模型中,它可降低血糖,强烈提高肝胰岛素敏感性并改善葡萄糖稳态。 了解更多
  48. SDF 1a Rat

    Catalog No. AP5771
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    Stromal Cell-Derived Factor-1 alpha Rat Recombinant (CXCL12) 了解更多
  49. SDF 1a Mouse

    Catalog No. AP5768
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    Stromal Cell-Derived Factor-1 Alpha Mouse Recombinant (CXCL12) 了解更多
  50. SDF 1a Mouse, His

    Catalog No. AP5767
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    Stromal Cell-Derived Factor-1 alpha (CXCL12), Mouse Recombinant, His Tag 了解更多

产品 151 到 200 共 642个

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