Decernotinib

目录号: A14012

JAK3 抑制剂

Decernotinib

Decernotinib Chemical Structure

CAS NO. 944842-54-0

Decernotinib是Vertex开发的口服选择性Janus激酶3(JAK3)抑制剂。

库存: 现货

规格 价格 数量
2 mg
¥ 420.00
5 mg
¥ 630.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Decernotinib是Vertex开发的口服选择性Janus激酶3(JAK3)抑制剂。
靶点信息
JAK3 JAK1 JAK1 JAK2 TYK2
2.5 nM(Ki)11 nM11 nM(Ki)13 nM(Ki)13 nM(Ki)
In vitro DMSO 70 mg/mL (178.39 mM)
Water Insoluble
Ethanol Warmed: 18 mg/mL (45.87 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.49 mL 127.43 mL 254.85 mL
0.5 mM 5.1 mL 25.49 mL 50.97 mL
1 mM 2.55 mL 12.74 mL 25.49 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 392.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14012
作用机制 Inhibitor (抑制剂)
M. Wt 392.38
Formula C18H19F3N6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 944842-54-0
Synonyms VX-509, VX509, VX 509, VRT-831509, VRT831509, VRT 831509
SMILES CC[C@](C)(C(=O)NCC(F)(F)F)NC1=NC(=NC=C1)C2=CNC3=C2C=CC=N3

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