Kenpaullone

目录号: A11220

CDK 抑制剂

Kenpaullone

Kenpaullone Chemical Structure

CAS NO. 142273-20-9

Kenpaullone是CDK1/细胞周期蛋白B(IC 50 = 400 nM),CDK2/细胞周期蛋白A(IC 50 = 680nM),CDK5(IC 50 = 850nM)的有效抑制剂,对其他激酶的作用要小得多。

库存: 现货 Shipped in 7-10 Days

规格 价格 数量
10 mg
¥ 630.00
50 mg
¥ 2,660.00
100 mg
¥ 4,550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Kenpaullone是CDK1/细胞周期蛋白B(IC 50 = 400 nM),CDK2/细胞周期蛋白A(IC 50 = 680nM),CDK5(IC 50 = 850nM)的有效抑制剂,对其他激酶的作用要小得多。
Targets
Target Value
GSK-3βIC50: 0.23μM
CDK1/CyclinBIC50: 0.4μM
CDK2/CyclinAIC50: 0.68μM
CDK5/p35IC50: 0.85μM
CDK2/CyclinEIC50: 7.5μM
ERK2IC50: 9μM
c-SrcIC50: 15μM
CaseinKinase2IC50: 20μM
ERK1IC50: 20μM
In vitro (25°C) DMSO 58 mg/mL (177.27 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+50% PEG 300+5% Tween 80+ddH2O 2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.56 mL 152.81 mL 305.62 mL
0.5 mM 6.11 mL 30.56 mL 61.12 mL
1 mM 3.06 mL 15.28 mL 30.56 mL
5 mM 0.61 mL 3.06 mL 6.11 mL

*The above data is based on the productmolecular weight 327.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11220
作用机制 Inhibitor (抑制剂)
M. Wt 327.2
Formula C16H11BrN2O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 142273-20-9
SMILES C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 Kenpaullone | Kenpaullone 供应商 | 订购 Kenpaullone | Kenpaullone 价格 | Kenpaullone 生产商 | 订单 Kenpaullone | Kenpaullone 代理商 | 购买 142273-20-9| 142273-20-9 供应商 | 订购 142273-20-9 | 142273-20-9 价格 | 142273-20-9 生产商 | 订单 142273-20-9 | 142273-20-9 代理商|buy Kenpaullone | Kenpaullone Supplier | purchase Kenpaullone | Kenpaullone cost | Kenpaullone manufacturer | order Kenpaullone | Kenpaullone distributor | buy 142273-20-9| 142273-20-9 Supplier | purchase 142273-20-9 | 142273-20-9 cost | 142273-20-9 manufacturer | order 142273-20-9 | 142273-20-9 distributor
Rewards