“angiotensin converting enzyme ace”的搜索结果
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JAK3 抑制剂
JAK3-IN-2 is a potent and highly selective JAK3 inhibitor with IC50 of 0.15 nM. dispalys >4,300-fold selectivity over JAK1, JAK2 and TYK2, and other kinases BMX, EGFR, ITK and BTK; blocks cytokine signaling through JAK3, but not through other JAK family enzymes; inhibits IL-7 induced pSTAT5 in CD3+, CD8+ T cells with IC50 of 280 nM; sufficiently blocks the development of inflammation in a rat model of rheumatoid arthritis, while sparing hematopoiesis.
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EGFR/HER2 dual 抑制剂
Pyrotinib Racemate是吡罗替尼的外消旋体。吡罗替尼是一种有效的选择性EGFR/HER2双重抑制剂。
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VEGFR/EGFR 抑制剂
Vandetanib trifluoroacetate是一种有效的VEGFR2抑制剂,IC50为40 nM。
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