“angiotensin converting enzyme ace”的搜索结果

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  1. Lisinopril

    Catalog No. A21064
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    angiotensin-converting enzyme inhibitor
    Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. 了解更多
  2. Imidaprilate

    Catalog No. A20003
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    ACE inhibitor
    Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease. 了解更多
  3. Zofenopril

    Catalog No. A13615
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    ACE inhibitor
    Zofenopril is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 81 μM. 了解更多
  4. H-Val-Pro-Pro-OH

    Catalog No. A18868
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    ACE inhibitor
    H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. 了解更多
  5. Malic enzyme inhibitor ME1

    Catalog No. A18564
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    ME1 inhibitor
    Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. 了解更多
  6. Omapatrilat

    Catalog No. A21059
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    ACE/NEP inhibitor
    Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with Ki values of 0.64 and 0.45 nM, respectively. 了解更多
  7. Ramipril

    Catalog No. A10778
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    ACE 抑制剂
    Ramipril是一种血管紧张素转化酶(ACE)抑制剂,IC50为5 nM。 了解更多
  8. Enalapril maleate

    Catalog No. A10350
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    ACE 抑制剂
    Enalapril maleate是一种血管紧张素转换酶(ACE)抑制剂,用于治疗高血压和某些类型的慢性心力衰竭。 了解更多
  9. Fosinopril sodium

    Catalog No. A11748
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    ACE 抑制剂
    Fosinopril sodium是一种血管紧张素转换酶(ACE)抑制剂,用于治疗高血压和某些类型的慢性心力衰竭。 了解更多
  10. (±)-WS75624B

    Catalog No. A12514
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    ECE inhibitor
    (±)-WS75624B is an endothelin converting enzyme (ECE) inhibitor with an IC50 of 0.03 μg/mL. 了解更多
  11. Apratastat

    Catalog No. A13330
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    dual TACE/MMPs inhibitor
    Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) . 了解更多
  12. Spinorphin

    Catalog No. A15314
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    Enkephalin-degrading and ACE 抑制剂
    Spinorphin是一种内源性因子,对脑啡肽降解酶具有抑制作用。 了解更多
  13. Zofenopril calcium

    Catalog No. A12769
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    ACE 抑制剂
    Zofenopril calcium是一种血管紧张素转化酶ACE抑制剂。 了解更多
  14. Temocapril

    Catalog No. A11749
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    ACE 抑制剂
    Temocapril是一种ACE抑制剂。 了解更多
  15. Cilazapril monohydrate

    Catalog No. A11747
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    ACE 抑制剂
    Cilazapril monohydrate是哒嗪血管紧张素转换酶抑制剂(ACE抑制剂),用于治疗高血压和充血性心力衰竭。 了解更多
  16. Benazepril HCl

    Catalog No. A10123
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    RAAS 抑制剂
    Benazepril hydrochloride是一种非肽血管紧张素转化酶(ACE)抑制剂。降低自发性高血压大鼠的血压和心肌肥大。 了解更多
  17. TD-0212

    Catalog No. A13715
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    neprilysin (NEP) inhibitor
    TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP. 了解更多
  18. LCZ696 (Valsartan)

    Catalog No. A14206
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    angiotensin receptor-neprilysin 抑制剂
    LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂(ARNi),用于治疗高血压和心力衰竭。 了解更多
  19. TAS4464 hydrochloride

    Catalog No. A21708
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    NEDD8 activating enzyme inhibitor
    TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM. 了解更多
  20. C527

    Catalog No. A21365
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    pan DUB enzyme inhibitor
    C527 is a is a pan DUB enzyme inhibitor, with a high potency for the USP1/UAF1 complex (IC50=0.88 μM). 了解更多
  21. CC0651

    Catalog No. A21188
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    Cdc34 ubiquitin-conjugating enzyme inhibitor
    CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27Kip1, as confirmed by dose-response analysis. 了解更多
  22. MUT056399

    Catalog No. A21084
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    FabI enzyme inhibitor
    MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively. 了解更多
  23. Bergaptol

    Catalog No. A12303
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    CYP3A4 enzyme inhibitor
    Bergaptol is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. Recent studies suggest that it may have antiproliferative and anticancer properties. 了解更多
  24. Vanin-1-IN-1

    Catalog No. A19095
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    Vanin-1 enzyme inhibitor
    Vanin-1-IN-1 is an inhibitor of vanin-1 enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation. 了解更多
  25. MSI-1436 lactate

    Catalog No. A21929
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    PTB1B inhibitor
    MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM). 了解更多
  26. PYZD-4409

    Catalog No. A21926
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    UBA1 inhibitor
    PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). 了解更多
  27. DG051

    Catalog No. A21891
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    leukotriene A4 hydrolase inhibitor
    DG051 is a potent leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis in the enzyme assay with an IC50=47 nM. 了解更多
  28. NS-2028

    Catalog No. A21643
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    sGC inhibitor
    NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity. 了解更多
  29. AZD3839 free base

    Catalog No. A21606
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    BACE1 inhibitor
    AZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor. 了解更多
  30. cis-Pralsetinib

    Catalog No. A21586
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    RET inhibitor
    cis-Pralsetinib (cis-BLU-667) is a highly potent and selective inhibitor of rearranged during transfection (RET), with IC50s ranging from 0.3 to 0.4 nM for WT RET and four enzyme variants (V804L, V804M, M918T, CCDC6-RET), and with broad, robust and anti-tumor activity against multiple RET-driven solid tumor types. 了解更多
  31. MSI-1436

    Catalog No. A21424
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    PTB1B inhibitor
    MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of appr 1 μM, 200-fold preference over TCPTP (IC50, 224 μM). 了解更多
  32. LY-2584702 hydrochloride

    Catalog No. A21416
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    p70S6K inhibitor
    LY-2584702 hydrochloride is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In S6K1 enzyme assay, the IC50 of LY-2584702 is 2 nM. 了解更多
  33. PF 750

    Catalog No. A21293
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    FAAH inhibitor
    PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme??s active site serine nucleophile. 了解更多
  34. CB30865

    Catalog No. A21209
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    Nampt inhibitor
    CB30865(ZM 242421) is a potent inhibitor of Nampt , an enzyme present in the NAD biosynthetic pathway. 了解更多
  35. SB 204990

    Catalog No. A21091
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    ACLY inhibitor
    SB 204990 is a potent and specific inhibitor of ATP citrate lyase (ACLY) enzyme. 了解更多
  36. 2,4-Diamino-6-hydroxypyrimidine

    Catalog No. A13500
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    GTP cyclohydrolase I inhibitor
    2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production. 了解更多
  37. Maribavir

    Catalog No. A20831
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    UL97 kinase inhibitor
    Maribavir is an UL97 kinase inhibitor potentially for the treatment of cytomegalovirus (CMV) infection. The mechanism by which maribavir inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97. 了解更多
  38. Umibecestat (CNP520)

    Catalog No. A18987
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    BACE-1 inhibitor
    Umibecestat (CNP520) is a beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) inhibitor with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. 了解更多
  39. Acetyllovastatin

    Catalog No. A19111
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    AChE inhibitor
    Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines. 了解更多
  40. LSN 3213128

    Catalog No. A19472
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    AICARFT inhibitor
    LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity. 了解更多
  41. PF-06751979

    Catalog No. A20066
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    BACE1 inhibitor
    PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay. 了解更多
  42. TAS4464

    Catalog No. A18485
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    NAE inhibitor
    TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM. 了解更多
  43. AZ1

    Catalog No. A18711
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    USP25/28 inhibitor
    AZ1 is a dual inhibitor of the USP25/28 deubiquitinating enzyme subfamily. 了解更多
  44. MAC13772

    Catalog No. A18788
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    BioA inhibitor
    MAC13772 is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound. 了解更多
  45. GLPG0259

    Catalog No. A18357
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    MAPKAPK5 inhibitor
    GLPG-0259 is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways 了解更多
  46. Metyrosine

    Catalog No. A18358
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    TYROSINE 3-MONOOXYGENASE inhibitor
    Metyrosine is an inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE. 了解更多
  47. ZM223

    Catalog No. A17174
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    NEDD8 activating enzyme (NAE) 抑制剂
    ZM223是一种非磺酰胺NEDD8活化酶(NAE)抑制剂,可抑制HCT116结肠癌细胞,IC50值为100 nM。 了解更多
  48. SW033291

    Catalog No. A15798
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    15-PGDH enzyme 抑制剂
    SW033291是15-PGDH的小分子抑制剂(Ki = 0.1 nM),可增加骨髓和其他组织中前列腺素PGE2的水平。 了解更多
  49. TBB

    Catalog No. A15257
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    CK2 抑制剂
    TBB是酪蛋白激酶2(CK2)的高选择性,ATP/GTP竞争性抑制剂,对大鼠肝脏和人重组CK2的IC50分别为0.9和1.6 uM。 了解更多
  50. Bay 11-7821

    Catalog No. A11957
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    E2 ubiquitin conjugating enzyme 抑制剂
    Bay 11-7821是TNF-α刺激的IκBα磷酸化的不可逆抑制剂。 了解更多

产品 1 到 50 共 202个

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