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HSP70-IN-1
Catalog No. A21716 HSP inhibitorHSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM. 了解更多 -
3-Methoxytyramine
Catalog No. A21676 neuromodulator3-Methoxytyramine, a well known extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator. 了解更多 -
nor-NOHA acetate
Catalog No. A21673 Arginase inhibitornor-NOHA acetate is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. 了解更多 -
Blasticidin S
Catalog No. A21608 Protein synthesis inhibitorBlasticidin S is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. Blasticidin S is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells. 了解更多 -
KRN2 bromide
Catalog No. A21549 NFAT5 inhibitorKRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. 了解更多 -
MitoTam iodide, hydriodide
Catalog No. A21486 ETC inhibitorMitoTam iodide, hydriodide is a tamoxifen derivative, an electron transport chain (ETC) inhibitor, spreduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology. 了解更多 -
Plecanatide acetate
Catalog No. A21393 GC-C receptor agonistPlecanatide acetate is a guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis. 了解更多 -
PhiKan 083 hydrochloride
Catalog No. A21372 PhiKan 083 hydrochloride is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells. 了解更多 -
Rabacfosadine
Catalog No. A21217 cytotoxic agentRabacfosadine (GS-9219), a novel prodrug of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells. 了解更多 -
ELN-441958
Catalog No. A21207 B1 receptor antagonistELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. 了解更多 -
Oglufanide
Catalog No. A21151 Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections. 了解更多 -
Phenoxodiol
Catalog No. A21147 Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. 了解更多 -
Kif15-IN-1
Catalog No. A21092 Kif15 inhibitorKif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15), and is used for the research of cellular proliferative diseases. 了解更多 -
Kif15-IN-2
Catalog No. A21088 Kif15 inhibitorKif15-IN-2 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases. 了解更多 -
Antitumor agent-3
Catalog No. A21062 Antitumor agent-3 is a potent compound which comprises a new imidazopyridine having excellent antitumor activity as an active ingredient. 了解更多 -
MIR96-IN-1
Catalog No. A20926 MicroRNA InhibitorMIR96-IN-1 is a selective inhibitor of the biogenesis of microRNA-96. It acts by upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells. 了解更多 -
Tyrphostin A1
Catalog No. A20916 Tyrphostin A1(AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells. 了解更多 -
Forodesine
Catalog No. A20903 PNP inhibitorForodesine(BCX-1777 freebase; Immucillin-H) is an orally bioavailable PNP inhibitor with picomolar potency; induces apoptosis, mainly in T cells. 了解更多 -
Targapremir-210
Catalog No. A20886 miR-210 inhibitorTargapremir-210 is a potent miR-210 inhibitor with an IC50 of 200 nM in MDA-MB-231 cells. Targapremir-210 binds to the Dicer site of the miR-210 hairpin precursor. This interaction inhibits production of the mature miRNA. 了解更多 -
VU 0240551
Catalog No. A20854 KCC2 inhibitorVU 0240551 is a small molecule inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2-overexpressing cells). 了解更多 -
Terlipressin
Catalog No. A17990 vasoconstrictorTerlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. 了解更多 -
Diclofenac
Catalog No. A17814 COX inhibitorDiclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. 了解更多 -
Amsacrine hydrochloride
Catalog No. A17707 antineoplastic agentAmsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. 了解更多 -
Megakaryocytes/platelets inducing agent
Catalog No. A13220 Megakaryocytes/platelets inducing agent is an inducing agent for megakaryocytes and/or platelets from pluripotent stem cells, the inducing agent being useful in treating diseases involving thrombopenia. 了解更多 -
Darbufelone mesylate
Catalog No. A11789 PGF2α/LTB4 production inhibitorDarbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM). 了解更多 -
Silvestrol aglycone
Catalog No. A11575 Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively. Anti-cancer activity. 了解更多 -
Canertinib dihydrochloride
Catalog No. A11344 EGFR inhibitorCanertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. 了解更多 -
Gemcitabine
Catalog No. A11434 DNA synthesis inhibitorGemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively. 了解更多 -
Seocalcitol
Catalog No. A11569 Seocalcitol is a vitamin D analog, binds vitamin D receptor protein from human osteosarcoma MG-63 cells with Kd of 0.27 nM. 了解更多 -
STAT3-IN-1
Catalog No. A12232 STAT3 inhibitorSTAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC50 values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor apoptosis. 了解更多 -
Clofilium tosylate
Catalog No. A12267 Clofilium tosylate, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. Antiarrhythmic agent. 了解更多 -
2',3'-cGAMP
Catalog No. A12277 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 了解更多 -
Ubiquitin Isopeptidase Inhibitor I, G5
Catalog No. A12293 apoptosis activatorUbiquitin Isopeptidase Inhibitor I, G5 (NSC 144303) is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively. 了解更多 -
Sulfosuccinimidyl oleate
Catalog No. A12606 Mitochondrial respiratory chain inhibitorSulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor of mitochondrial respiratory chain. 了解更多
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