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Homosalate
Catalog No. A22302 chemical UV filterHomosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage. 了解更多 -
Ribociclib hydrochloride
Catalog No. A22303 CDK4/6 inhibitorRibociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, 了解更多 -
BDTX-189
Catalog No. A22306 Anticancer agentBDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity. 了解更多 -
LDN-193189 2HCl
Catalog No. A22307 BMP signaling inhibitorLDN193189 HCl (DM-3189) is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β. 了解更多 -
BpV(HOpic)
Catalog No. A22308 PTEN inhibitorBpV(HOpic) is a potent and selective inhibitor of PTEN with an IC50 of 14 nM. Nanocarrier-BpV(HOpic) has neuroprotective activity. 了解更多 -
2-Phospho-L-ascorbic acid trisodium
Catalog No. A22309 antioxidant2-Phospho-L-ascorbic acid trisodium acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. 了解更多 -
Ferulic acid sodium
Catalog No. A22310 FGFR1 inhibitorFerulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. 了解更多 -
L-Quebrachitol
Catalog No. A22312 natural productL-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway. 了解更多 -
Loureirin A
Catalog No. A22313 flavonoidLoureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity. 了解更多 -
Kaempferol 3-neohesperidoside
Catalog No. A22314 flavonoidKaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid. Kaempferol 3-neohesperidoside exhibits insulinomimetic effect on the rat soleus muscle. 了解更多 -
Higenamine
Catalog No. A22315 β2-AR agonistHigenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. 了解更多 -
Alflutinib
Catalog No. A22316 EGFR inhibitorAlflutinib is an EGFR inhibitor that targets both EGFR activating mutations and T790M, thus leading to tumor growth inhibition. 了解更多 -
DCLK1-IN-1
Catalog No. A22319 chemical probeDCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. 了解更多 -
Remibrutinib
Catalog No. A22322 BTK inhibitorRemibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. 了解更多 -
Benzamidine hydrochloride
Catalog No. A22323 trypsin-like serine proteases inhibitorBenzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 ?M, 21 ?M, 20 ?M and 110 ?M for uPA, trypsin, tryptase and factor Xa, respectively. 了解更多 -
Ehp inhibitor 2
Catalog No. A22325 Eph family tyrosine kinase inhibitorEhp inhibitor 2 is a Eph family tyrosine kinase inhibitor. 了解更多 -
IRAK4-IN-4
Catalog No. A22333 IRAK4 inhibitorIRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. 了解更多 -
Mobocertinib
Catalog No. A22334 inhibitor of EGFR and HER2 oncogenic mutantsMobocertinib (TAK-788) is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity. 了解更多 -
BSJ-03-123
Catalog No. A22336 CDK6-selective small-molecule degraderBSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC). 了解更多 -
Decursinol angelate
Catalog No. A22340 cytotoxic and protein kinase C (PKC) activating agentDecursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities. 了解更多 -
3'-Hydroxypterostilbene
Catalog No. A22341 natural pterostilbene analogue3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 ?M for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 了解更多 -
7-Nitroindazole
Catalog No. A22342 neuronal nitric oxide synthase inhibitor7-Nitroindazole, a heterocyclic compound, acts as a selective inhibitor for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS. 了解更多 -
Chromium picolinate
Catalog No. A22343 nutritional supplementChromium picolinate is a coordination complex consisting of chromium(III) and picolinic acid. It is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. 了解更多 -
Dihydrocaffeic acid
Catalog No. A22344 Antioxidant agentDihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity. 了解更多 -
JNJ-38158471
Catalog No. A22345 VEGFR-2 inhibitorJNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively. 了解更多 -
3-Deazaadenosine hydrochloride
Catalog No. A22347 inhibitor of S-adenosylhomocysteine hydrolase3-Deazaadenosine (hydrochloride) is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 ?M; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIV activity. 了解更多 -
CCG-222740
Catalog No. A22348 MRTF pathway inhibitorCCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor. CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. 了解更多
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