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Pramipexole dihydrochloride monohyrate
Catalog No. A10747 Dopamine Receptor 激动剂Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂，适用于治疗早期帕金森氏病（PD）和不安腿综合征（RLS）。 了解更多 -
B-HT 920 2HCl
Catalog No. A11341 -
Rotigotine
Catalog No. A11553 -
Naxagolide
Catalog No. A13087 -
ent Naxagolide Hydrochloride
Catalog No. A13089 dopamine D2-receptor 激动剂ent Naxagolide Hydrochloride是一种多巴胺D2受体激动剂，用于治疗锥体外系疾病。该化合物是抗帕金森病药物。 了解更多 -
Pergolide Mesylate
Catalog No. A14179 -
(+) PD 128907
Catalog No. A14376 Dopamine receptor 激动剂(+)-PD 128907 hydrochloride是一种有效的D3DR（多巴胺受体）激动剂（Ki = 2.3 nM）。 了解更多 -
Bromocriptin mesylate
Catalog No. A13705 dopamine D2 receptor 激动剂Bromocriptin mesylate是一种有效的多巴胺受体激动剂，它以最高的亲和力（Ki = 2.5 nM）与D2受体结合。 了解更多 -
Brexpiprazole
Catalog No. A13527 D2 dopamine partial 激动剂Brexpiprazole是一种新型的D2多巴胺部分激动剂研究产品，目前正在临床试验中，用于治疗抑郁症，精神分裂症和注意缺陷多动障碍（ADHD）。 了解更多 -
Dexpramipexole dihydrochloride
Catalog No. A15066 -
rac-Rotigotine Hydrochloride
Catalog No. A15217 -
UNC 9994 hydrochloride
Catalog No. A16087 dopamine D2 receptor 激动剂UNC 9994 hydrochloride，独特的，β-arrestin偏向的功能选择性多巴胺D2受体（D2R）激动剂（Ki值为30 nM；在ε-arrestin-2募集试验中EC50值为50 nM），在体内具有抗精神病活性。UNC9994在野生型小鼠中显着抑制了PCP诱导的超运动，而在Δr-arrestin-2基因敲除小鼠中这种作用被完全消除。 了解更多 -
TRV130 HCl (Oliceridine)
Catalog No. A15444 u-opioid receptor 激动剂TRV130 HCl (Oliceridine)是一种新型的μ-opioid 受体（MOR）G蛋白偏向配体。诱导强大的G蛋白信号传导（pEC50 = 8.1），效力和功效与吗啡相似，但β-arrestin募集和受体内在化作用要低得多。 了解更多 -
CYT-1010 hydrochloride
Catalog No. A21348 mu-opioid receptor agonistCYT-1010 hydrochloride is a mu-opioid receptor agonist extracted from patent WO2013173730A2, with EC50s of 13.1 nM and 0.0053 nM on beta-arrestin recruitment and inhibition of cAMP production, respectively. 了解更多 -
AR-M 1000390 hydrochloride
Catalog No. A21911 δ opioid receptor agonistAR-M 1000390 hydrochloride is an exceptionally selective, potent δ opioid receptor agonist with an EC50 of 7.2??0.9 nM for δ agonist potency. 了解更多 -
ADL5859 HCl
Catalog No. A11072 Opioid Receptor 激动剂ADL5859 HCl是高效的选择性δ阿片受体激动剂，Ki值为0.84 nM，ED50值为20 nM。 了解更多 -
MCOPPB 3HCl
Catalog No. A10561 -
BRL 52537 HCl
Catalog No. A11210 Opioid Receptors 激动剂BRL 52537 hydrochloride是一种高度选择性和有效的κ阿片类激动剂（Ki = 0.24 nM）。比吗啡强25倍。 了解更多 -
Nalfurafine hydrochloride
Catalog No. A12579 opioid κ-selective 激动剂Nalfurafine hydrochloride是一种κ-opioid激动剂。 了解更多 -
U-69593
Catalog No. A14187 -
Alvimopan dihydrate
Catalog No. A14991 ?-opioid receptor 激动剂Alvimopan dihydrate (LY 246736,ADL 8-2698)是一种外周作用的类阿片受体（PAM-OR，IC50 = 1.7 nM）拮抗剂，可促进术后胃肠道恢复。 了解更多 -
Alvimopan monohydrate
Catalog No. A14992 ?-opioid receptor 激动剂Alvimopan monohydrate是一种外围作用的类阿片受体（PAM-OR，IC50 = 1.7 nM）拮抗剂，可促进术后肠胃的恢复。 了解更多 -
Cebranopadol (GRT-6005)
Catalog No. A12670 Opioid Receptor 激动剂Cebranopadol是一种有效的伤害感受器/孤儿蛋白FQ肽（NOP）和阿片受体激动剂。作用于人NOP，MOP，KOP 和δ-阿片肽(DOP)受体，Ki/EC50 分别为 0.9 nM/13 nM，0.7 nM/1.2 nM，2.6 nM/17 nM，18 nM/110 nM。 了解更多 -
Trimebutine maleate
Catalog No. A18115 ?- opioid receptor agonistTrimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. 了解更多 -
O-Phospho-L-serine
Catalog No. A21159 group III mGluR receptors agonistO-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. 了解更多 -
(1R,2S)-VU0155041
Catalog No. A21933 partial mGluR4 agonist(1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM. 了解更多 -
CHPG sodium salt
Catalog No. A21968 mGluR5 agonistCHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. 了解更多 -
LY2140023 (LY404039)
Catalog No. A10544 mGluR 激动剂LY-404039是一种用于科学研究的药物，用作代谢型谷氨酸受体II亚型mGluR2和mGluR3的选择性激动剂。它在动物研究中具有抗焦虑和抗精神病作用，但不会引起镇静作用。早期的人体试验使用LY-404，039前药形式LY-214，0023，也取得了令人鼓舞的结果。 了解更多 -
Ibotenic Acid
Catalog No. A14006 NMDA& mGlu receptor 激动剂Ibotenic Acid是最初从鹅膏菌属物种中分离出来的一种神经兴奋性氨基酸，它起着NMDA和代谢型谷氨酸受体激动剂的作用。 了解更多 -
Kainic acid monohydrate
Catalog No. A13485 Kainate receptor 激动剂Kainic acid monohydrate是海藻酸酯类离子型谷氨酸受体激动剂。可在体内诱发癫痫发作和神经退行性变，也已用于在啮齿动物中诱发实验性癫痫和检查兴奋性诱发的神经元凋亡机制。 了解更多 -
(S)-3,5-DHPG
Catalog No. A16108 mGluR 激动剂(S)-3,5-DHPG是I类代谢型谷氨酸受体（mGluRs）的激动剂，与mGluR1a和mGluR5a（分别为Ki = 0.9和3.9 uM）结合，但不与离子型谷氨酸受体结合。 了解更多 -
Tasimelteon
Catalog No. A17351 MT1 and MT2 receptor agonistTasimelteon is a melatonin MT1 and MT2 receptor agonist. 了解更多 -
Melatonin
Catalog No. A10564 -
Ramelteon (TAK-375)
Catalog No. A10777 MT1/MT2-Receptor 激动剂Ramelteon (TAK-375)是melatonin受体激动剂，对褪黑激素MT1（IC50 = 28.5±8.55 pM）和MT2（20.1±9.25 pM）受体均具有高亲和力，并且相对于MT3受体具有选择性。 了解更多 -
SAG
Catalog No. A13627 -
SAG hydrochloride
Catalog No. A21678 Smo receptor agonistSAG (hydrochloride) is a potent Smo receptor agonist, and activates the Hedgehog signaling pathway, with a Kd of 59 nM. 了解更多 -
GPR35 agonist 1
Catalog No. A12462 GPR35/CXCR8 agonistGPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good druggability. 了解更多 -
Kynurenic acid sodium
Catalog No. A20000 GPR35/CXCR8 agonistKynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8. 了解更多
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