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Deoxygalactonojirimycin HCl
Catalog No. A14016 Alpha-galactosidase 抑制剂Deoxygalactonojirimycin Hydrochloride是一种有效且选择性的Alpha-gal A（Alpha-半乳糖苷酶）抑制剂。 了解更多 -
BOP sodium salt
Catalog No. A17201 -
Anisodamine
Catalog No. A18215 alpha-1 adrenergic receptors / mAChRs inhibitorAnisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. 了解更多 -
Epristeride
Catalog No. A18231 5 alpha-reductase inhibitorEpristeride is a selective and specific uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. 了解更多 -
Pictilisib dimethanesulfonate
Catalog No. A11444 PI3Kα/δ inhibitorPictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). 了解更多 -
MD2-TLR4-IN-1
Catalog No. A18452 MD2-TLR4 inhibitorMD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多 -
STF-083010
Catalog No. A16720 IRE1α inhibitorSTF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress. 了解更多 -
ZINC13466751
Catalog No. A12522 HIF-1α/von Hippel-Lindau interaction inhibitorZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 ?M. 了解更多 -
Darbufelone mesylate
Catalog No. A11789 PGF2α/LTB4 production inhibitorDarbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM). 了解更多 -
Emiglitate
Catalog No. A20917 α-glucoside hydrolase inhibitorEmiglitate (BAY o 1248) is a potent, selective and competitive inhibitor of α-glucoside hydrolase. 了解更多 -
R1487 Hydrochloride
Catalog No. A21231 p38α inhibitorsR1487 (Hydrochloride) is highly potent and highly selective inhibitors of p38α. 了解更多 -
(Rac)-PT2399
Catalog No. A21376 HIF-2α inhibitor(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM. 了解更多 -
CHIR-99021 monohydrochloride
Catalog No. A21430 GSK-3α/β inhibitorCHIR-99021 monohydrochloride (CT99021 monohydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. 了解更多 -
CHIR-99021 trihydrochloride
Catalog No. A21436 GSK-3α/β inhibitorCHIR-99021 trihydrochloride (CT99021 trihydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM. 了解更多 -
Finasteride acetate
Catalog No. A21537 testosterone 5-alpha-reductase inhibitorFinasteride (acetate) is an orally active testosterone 5-alpha-reductase inhibitor. 了解更多 -
Dehydroaltenusin
Catalog No. A21804 eukaryotic DNA polymerase α inhibitorDehydroaltenusin is a small molecule selective inhibitor of eukaryotic DNA polymerase α, a type of antibiotic produced by a fungus with an IC50 value of 0.68 μM. 了解更多 -
DO34 analog
Catalog No. A21821 triazole DAGL(α) inhibitorDO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100. 了解更多 -
MW-150 hydrochloride
Catalog No. A21854 p38α MAPK inhibitorMW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. 了解更多 -
MW-150 dihydrochloride dihydrate
Catalog No. A21860 p38α MAPK inhibitorMW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. 了解更多 -
BMS-582949 hydrochloride
Catalog No. A21914 p38α MAPK inhibitorBMS-582949 hydrochloride is an orally active and highly selective p38α MAPK inhibitor, with an IC50 of 13 nM. 了解更多 -
Ralimetinib
Catalog No. A21942 p38 MAPK α/β inhibitorRalimetinib (LY2228820) is a potent and selective, ATP-competitive inhibitor of p38 MAPK α/β, with IC50s of 5.3 and 3.2 nM, respectively. 了解更多 -
Carotegrast
Catalog No. A21997 α4 integrin receptor inhibitorCarotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities. 了解更多 -
Cyclo(RGDyK)
Catalog No. A21819 αVβ3 integrin inhibitorCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM. 了解更多 -
PI3K-alpha inhibitor 1
Catalog No. A16274 PI3Kα 抑制剂PI3K-alpha inhibitor 1 是从专利US/20120088764A1中提取的PI3Kα抑制剂，化合物243，IC50 <0.1uM，PI3Kα抑制剂1还抑制HDAC（0.1uM≤IC50≤1uM）。 了解更多 -
Pifithrin-alpha
Catalog No. A12451 p53 抑制剂Pifithrin-alpha是p53介导的细胞凋亡和p53依赖性基因转录（如细胞周期蛋白G，p21/waf1和mdm2表达）的可逆抑制剂。 了解更多 -
Alpha-Naphthoflavone
Catalog No. A18474 aromatase inhibitorAlpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. 了解更多 -
MAC glucuronide α-hydroxy lactone-linked SN-38
Catalog No. A18407 Topoisomerase I inhibitorMAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 drug linker. 了解更多 -
p38-α MAPK-IN-1
Catalog No. A21036 MAPK14 inhibitorp38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. 了解更多 -
Pomalidomide (CC-4047)
Catalog No. A10743 TNF-alpha 抑制剂Pomalidomide (CC-4047)是沙利度胺的衍生物，在PBMCs中IC50为13 nM，并起免疫调节剂的作用。 了解更多 -
β-Sitosterol
Catalog No. A11015 -
CUDC-305 (DEBIO-0932 )
Catalog No. A12648 HSP90 抑制剂CUDC-305 (DEBIO-0932) 是一种新型的热休克蛋白90（HSP90）抑制剂，对HSP90 alpha/beta具有很强的亲和力，对HSP90α和HSP90β的IC50值分别为100和103nM。具有很高的口服生物利用度，并且对多种癌细胞系均具有强大的抗增殖活性（平均IC50为220 nmol/L）。包括许多对护理标准（SOC）药物有抵抗力的非小细胞肺癌（NSCLC）细胞系。 了解更多 -
Celgosivir
Catalog No. A13118 -
Cyclopiazonic Acid
Catalog No. A14002 SERCA 抑制剂Cyclopiazonic acid是SERCA（内质网Ca2+ -ATPase）的抑制剂，可诱导细胞内储存的Ca2+释放，而不会增加IP3水平。 了解更多 -
SR 18292
Catalog No. A16914 -
Obtustatin
Catalog No. A17185 α1β1 抑制剂Obtustatin是高度有效的整联蛋白α1β1抑制剂（α1β1与IV型胶原的结合的IC 50 = 0.8 nM）。与α2β1，βIIbβ3，αvβ3，α4β1，β5β6，α9β1和α4β7相比，α1β1具有选择性。在鸡绒膜尿囊炎模型中抑制FGF2刺激的血管生成。在Lewis肺癌的协同小鼠模型中显示抗肿瘤功效；阻止人黑素瘤在裸鼠中的生长。 了解更多
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