“rasgap ras p21”的搜索结果

产品 51 到 100 共 312个

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  1. R 80123

    Catalog No. A21836
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    phosphodiesterase inhibitor
    R 80123 is the Z-isomer of R 79595, is also a highly selective phosphodiesterase inhibitor. 了解更多
  2. Prasugrel (Maleic acid)

    Catalog No. A21832
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    platelet inhibitor
    Prasugrel (PCR 4099) Maleic acid is a platelet inhibitor with IC50 value of 1.8 μM. 了解更多
  3. Daun02

    Catalog No. A21818
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    prodrug of the topoisomerase inhibitor Daunorubicin
    Daun02 is a prodrug of the topoisomerase inhibitor Daunorubicin. 了解更多
  4. BIX-01338 hydrate

    Catalog No. A21812
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    histone lysine methyltransferase inhibitor
    BIX-01338 hydrate is a histone lysine methyltransferase inhibitor. 了解更多
  5. Lumicitabine

    Catalog No. A21807
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    RSV polymerase inhibitor
    Lumicitabine (ALS-008176) is an inhibitor of the respiratory syncytial virus (RSV) polymerase. 了解更多
  6. Dehydroaltenusin

    Catalog No. A21804
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    eukaryotic DNA polymerase α inhibitor
    Dehydroaltenusin is a small molecule selective inhibitor of eukaryotic DNA polymerase α, a type of antibiotic produced by a fungus with an IC50 value of 0.68 μM. 了解更多
  7. VP3.15 dihydrobromide

    Catalog No. A21789
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    PDE7/GSK3 inhibitor
    VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. 了解更多
  8. Tipifarnib S enantiomer

    Catalog No. A21787
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    FTase inhibitor
    Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer. 了解更多
  9. PSI-6206 13CD3

    Catalog No. A21782
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    HCV NS5B polymerase inhibitor
    PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. 了解更多
  10. K-604 dihydrochloride

    Catalog No. A21773
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    ACAT-1 inhibitor
    K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45??0.06 μM. 了解更多
  11. Nevanimibe hydrochloride

    Catalog No. A21767
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    ACAT1 inhibitor
    Nevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. 了解更多
  12. NM107

    Catalog No. A21761
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    HCV NS5B polymerase
    NM107 (2'-C-Methylcytidine) is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, the EC50 of NM107 in the wild-type replicon cells is 1.85 μM. 了解更多
  13. BAY 73-6691 racemate

    Catalog No. A21745
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    PDE9 inhibitor
    BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1. 了解更多
  14. GSK3368715 dihydrochloride

    Catalog No. A21733
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    PRMT inhibitor
    GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). 了解更多
  15. Dxd

    Catalog No. A21517
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    DNA topoisomerase I inhibitor
    Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a). 了解更多
  16. Exatecan Mesylate

    Catalog No. A21515
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    DNA topoisomerase I inhibitor
    Exatecan Mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. 了解更多
  17. Beclabuvir

    Catalog No. A21511
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    HCV NS5B RNA-dependent RNA polymerase inhibitor
    Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. 了解更多
  18. AMG 579

    Catalog No. A21478
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    PDE10A inhibitor
    AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. 了解更多
  19. VXc-?486

    Catalog No. A21471
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    gyrase B inhibitor
    VXc-486 is a gyrase B inhibitor, with bactericidal activity. 了解更多
  20. (R)-Rivastigmine D6 tartrate

    Catalog No. A21454
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    cholinesterase inhibitor
    (R)-Rivastigmine D6 (tartrate) is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor. 了解更多
  21. CVT-12012

    Catalog No. A21447
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    SCD inhibitor
    CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively. 了解更多
  22. Saterinone hydrochloride

    Catalog No. A21402
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    PDE3 inhibitor
    Saterinone hydrochloride is a phosphodiesterase III (PDE III) inhibitor. 了解更多
  23. Filibuvir

    Catalog No. A21392
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    non-nucleoside inhibitor
    Filibuvir is a potent, selective non-nucleoside inhibitor (NNI) of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, and it binds noncovalently in the ??Thumb 2?? pocket of NS5B. 了解更多
  24. ALS-8112

    Catalog No. A21374
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    RSV polymerase inhibitor
    ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM. 了解更多
  25. Rasagiline 13C3 mesylate racemic

    Catalog No. A21350
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    Monoamine oxidase inhibitor
    Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. 了解更多
  26. PF-06424439 methanesulfonate

    Catalog No. A21343
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    DGAT2 inhibitor
    PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. 了解更多
  27. Potassium oxonate

    Catalog No. A21302
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    uricase inhibitor
    Potassium oxonate is an inhibitor of uricase, inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and intact cells in vitro. 了解更多
  28. Mirodenafil

    Catalog No. A21260
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    PDE-5 inhibitor
    Mirodenafil(SK3530) is a phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. 了解更多
  29. Letermovir

    Catalog No. A21248
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    CMV inhibitor
    Letermovir is a novel inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. 了解更多
  30. Edotecarin

    Catalog No. A21233
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    Topoisomerase I inhibitor
    Edotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM. 了解更多
  31. Ezatiostat hydrochloride

    Catalog No. A21222
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    glutathione analog inhibitor
    Ezatiostat hydrochloride (TER199;TLK199 hydrochloride) is a glutathione analog inhibitor of glutathione S-transferase P1-1 (GSTP1-1). 了解更多
  32. BRD9539

    Catalog No. A21201
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    EHMT2 inhibitor
    BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 ?M. 了解更多
  33. Karenitecin

    Catalog No. A21156
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    topoisomerase I inhibitor
    Karenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity. 了解更多
  34. Namitecan

    Catalog No. A21146
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    topoisomerase I inhibitor
    Namitecan is a potent topoisomerase I inhibitor, with antitumor property. 了解更多
  35. LY 222306

    Catalog No. A21133
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    GARFT inhibitor
    LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM. 了解更多
  36. Gepotidacin

    Catalog No. A21086
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    topoisomerase II inhibitor
    Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. 了解更多
  37. Teglicar

    Catalog No. A21061
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    L-CPT1 inhibitor
    Teglicar is a selective and reversible inhibitor of liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1). 了解更多
  38. Galidesivir hydrochloride

    Catalog No. A20930
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    RdRp inhibitor
    Galidesivir hydrochloride (BCX 4430 hydrochloride) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor; demonstrated broad-spectrum activity in multiple viruses and a favorable preliminary preclinical safety profile. 了解更多
  39. D77

    Catalog No. A20905
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    anti-HIV-1 inhibitor
    D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. 了解更多
  40. FTI 276

    Catalog No. A20869
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    PFT inhibitor
    FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human. 了解更多
  41. Mirodenafil dihydrochloride

    Catalog No. A18047
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    PDE-5 inhibitor
    Mirodenafil dihydrochloride (SK3530 dihydrochloride) is a phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. 了解更多
  42. Pirarubicin Hydrochloride

    Catalog No. A18037
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    topoisomerase II inhibitor
    Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors. 了解更多
  43. Amsacrine hydrochloride

    Catalog No. A17707
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    antineoplastic agent
    Amsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. 了解更多
  44. Diethylcarbamazine citrate

    Catalog No. A16506
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    arachidonic acid metabolism inhibitor
    Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements. 了解更多
  45. Mericitabine

    Catalog No. A11539
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    HCV NS5B polymerase inhibitor
    Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication. 了解更多
  46. HIV-1 integrase inhibitor 2

    Catalog No. A11447
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    HIV-1 integrase inhibitor
    HIV-1 integrase inhibitor 2, in the treatment of human immunodeficiency virus (HIV) infection. 了解更多
  47. HIV-1 integrase inhibitor

    Catalog No. A11446
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    HIV-1 integrase inhibitor
    HIV-1 integrase inhibitor is uesful for anti-HIV. 了解更多
  48. O6BTG-octylglucoside

    Catalog No. A11432
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    MGMT inhibitor
    O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. 了解更多
  49. Sildenafil citrate

    Catalog No. A10841
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    PDE5 inhibitor
    Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM. 了解更多
  50. WM-8014

    Catalog No. A20006
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    MOZ inhibitor
    WM-8014 is an inhibitor of MOZ, a member of histone acetyltransferases, with an IC50 of 55 nM. 了解更多

产品 51 到 100 共 312个

每页
页面:
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  2. 2
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