“AZ 960”的搜索结果

产品 201 到 250 共 520个

每页
页面:
  1. 3
  2. 4
  3. 5
  4. 6
  5. 7

设置降序顺序
  1. 6-Methyl-5-azacytidine

    Catalog No. A13391
    Quick View
    DNMT inhibitor
    6-Methyl-5-azacytidine is a potent DNMT inhibitor. 了解更多
  2. CPUY074020

    Catalog No. A12190
    Quick View
    G9a inhibitor
    CPUY074020 is a potent G9a inhibitor with an IC50 of 2.18 μM, and possesses anti-proliferative activity . 了解更多
  3. GS-9901

    Catalog No. A12988
    Quick View
    PI3Kδ inhibitor
    GS-9901 is a highly selective and orally active PI3Kδ inhibitor, with an IC50 of 1 nM. Has potential to treat rheumatoid arthritis. 了解更多
  4. MBM-55

    Catalog No. A12510
    Quick View
    Nek2 inhibitor
    MBM-55 (compound 42g) is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM. 了解更多
  5. Pentiapine

    Catalog No. A12512
    Quick View
    dopamine release inhibitor
    Pentiapine is a novel dopamine release inhibitor. 了解更多
  6. Cdc7-IN-1

    Catalog No. A12513
    Quick View
    Cdc7 kinase inhibitor
    Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. 了解更多
  7. ZED-1227

    Catalog No. A12242
    Quick View
    transglutaminase 2 (TG2) inhibitor
    ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD). 了解更多
  8. Proteasome-IN-1

    Catalog No. A12254
    Quick View
    proteasome inhibitor
    Proteasome-IN-1 is a proteasome inhibitor extracted from patent WO 2013142376 A1. 了解更多
  9. Lanabecestat

    Catalog No. A12282
    Quick View
    BACE1 inhibitor
    Lanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. 了解更多
  10. CHMFL-EGFR-202

    Catalog No. A12524
    Quick View
    EGFR inhibitor
    CHMFL-EGFR-202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively. 了解更多
  11. CHMFL-BTK-01

    Catalog No. A12538
    Quick View
    BTK inhibitor
    CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation. 了解更多
  12. Dot1L-IN-1

    Catalog No. A12552
    Quick View
    Dot1L inhibitor
    Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM. 了解更多
  13. Nrf2-IN-1

    Catalog No. A12561
    Quick View
    Nrf2 inhibitor
    Nrf2-IN-1 (Compound 4f) is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2), acts as a promising agent in acute myeloid leukemia (AML) therapy. 了解更多
  14. APG-115

    Catalog No. A12575
    Quick View
    MDM2 inhibitor
    APG-115 (AA-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively. 了解更多
  15. PF-06424439

    Catalog No. A12608
    Quick View
    DGAT2 inhibitor
    PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. 了解更多
  16. CYP17-IN-1

    Catalog No. A12622
    Quick View
    CYP17 inhibitor
    CYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM. 了解更多
  17. EGFR-IN-2

    Catalog No. A12628
    Quick View
    EGFR inhibitor
    EGFR-IN-2 is a a noncovalent, irreversible, mutant-selective second generation EGFR inhibitor. 了解更多
  18. KRas G12C inhibitor 3

    Catalog No. A13018
    Quick View
    Kras-G12C inhibitor
    KRas G12C inhibitor 3 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多
  19. TTT-28

    Catalog No. A13033
    Quick View
    ABCB1 (P-gp/MDR1) inhibitor
    TTT-28 is a synthesized thiazole-valine peptidomimetic, a novel selective inhibitor of ABCB1 (P-gp/MDR1) with high efficacy and low toxicity. 了解更多
  20. mTOR inhibitor-2

    Catalog No. A13035
    Quick View
    mTOR inhibitor
    mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates. 了解更多
  21. Conteltinib

    Catalog No. A13037
    Quick View
    multi-kinase inhibitor
    Conteltinib (CT-707) is a multi-kinase inhibitor targeting FAK, ALK, and Pyk2. Conteltinib (CT-707) exerts significant inhibitory effect on FAK with an IC50 of 1.6 nM. 了解更多
  22. ICA

    Catalog No. A13062
    Quick View
    SK channel inhibitor
    ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 ?M. 了解更多
  23. KRas G12C inhibitor 2

    Catalog No. A13064
    Quick View
    Kras-G12C inhibitor
    KRas G12C inhibitor 2 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多
  24. CHK1-IN-2

    Catalog No. A13142
    Quick View
    CHK1 inhibitor
    CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM. 了解更多
  25. KRas G12C inhibitor 1

    Catalog No. A13152
    Quick View
    Kras-G12C inhibitor 1
    KRas G12C inhibitor 1 is a compound that inhibits KRas G12C, extracted from patent US 20180072723 A1. 了解更多
  26. WNK-IN-11

    Catalog No. A13153
    Quick View
    WNK inhibitor
    WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1. 了解更多
  27. EBI-1051

    Catalog No. A13176
    Quick View
    MEK inhibitor
    EBI-1051 is a highly potent and orally efficacious MEK inhibitor with an IC50 of 3.9 nM. 了解更多
  28. CHMFL-ABL-039

    Catalog No. A13182
    Quick View
    BCR-ABL inhibitor
    CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor with the IC50s of 7.9 nM and 27.9 nM, respectively. CHMFL-ABL-039 is used in the research of chronic myeloid leukemia. 了解更多
  29. MMP3 inhibitor 1

    Catalog No. A13185
    Quick View
    MMP-3 inhibitor
    MMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with an IC50 of 1 nM. 了解更多
  30. AZD3988

    Catalog No. A13208
    Quick View
    DGAT-1 inhibitor
    AZD3988 is a diacylglycerol acyl transferase-1 (DGAT-1) inhibitor with IC50s of 6, 5, 11 nM for human, rat, mouse, respectively. 了解更多
  31. MA242

    Catalog No. A13480
    Quick View
    dual MDM2/NFAT1 inhibitor
    MA242 is a dual inhibitor of murine double minute 2 (MDM2) and nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy. 了解更多
  32. Istaroxime

    Catalog No. A15130
    Quick View
    Na+,K+-ATPase inhibitor
    Istaroxime (PST2744) is a potent inhibitor of Na+,K+-ATPase with IC50 of 0.11 μM. 了解更多
  33. MMV390048

    Catalog No. A13566
    Quick View
    PI4K inhibitor
    MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 ?M). 了解更多
  34. PDE9-IN-1

    Catalog No. A13599
    Quick View
    PDE9A Inhibitor
    PDE9-IN-1 is a potent, selective, and orally bioavailable phosphodiesterase-9A (PDE9A) Inhibitor with an IC50 of 8.7 nM. 了解更多
  35. YZ129

    Catalog No. A13601
    Quick View
    HSP90-calcineurin-NFAT inhibitor
    YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. 了解更多
  36. SPL-707

    Catalog No. A13669
    SPPL2a inhibitor
    SPL-707 is a potent, selective and orally available signal peptide peptidase-like 2a (SPPL2a) inhibitor with an IC50 of 80 nM. 了解更多
  37. JNJ4796

    Catalog No. A13707
    Quick View
    Influenza virus inhibitor
    JNJ4796 is an oral active fusion inhibitor of influenza virus, neutralizing influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion. 了解更多
  38. Epertinib

    Catalog No. A13777
    Quick View
    EGFR/HER2/HER4 inhibitor
    Epertinib is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity. 了解更多
  39. GGTI298 Trifluoroacetate

    Catalog No. A16560
    Quick View
    GGTase I inhibitor
    GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM. 了解更多
  40. Mebendazole

    Catalog No. A16606
    Quick View
    Hedgehog inhibitor
    Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor. 了解更多
  41. Lansoprazole

    Catalog No. A10513
    Quick View
    proton pump inhibitor
    Lansoprazole(AG 1749) is a proton pump inhibitor which prevents the stomach from producing acid. 了解更多
  42. Vilazodone Hydrochloride

    Catalog No. A11604
    Quick View
    serotonin transporter (SER) inhibitor
    Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist. 了解更多
  43. TPOP146

    Catalog No. A12655
    Quick View
    CBP/P300 benzoxazepine bromodomain inhibitor
    TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4. 了解更多
  44. MELK-IN-1

    Catalog No. A12675
    Quick View
    MELK inhibitor
    MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.39 nM, respectively. 了解更多
  45. GNA002

    Catalog No. A13266
    Quick View
    EZH2 inhibitor
    GNA002 is a highly potent, specific and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor with an IC50 of 1.1 μM. 了解更多
  46. MIV-150

    Catalog No. A12060
    Quick View
    NNRT inhibitor
    MIV-150 is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC50<1 nM against HIV-1/HIV-2MN. 了解更多
  47. ZD-0892

    Catalog No. A13303
    Quick View
    neutrophil elastase inhibitor
    ZD-0892 is a selective and potent inhibitor of a neutrophil elastase with Kis of 6.7 and 200 nM for human neutrophil elastase and porcine pancreatic elastase, respectively. 了解更多
  48. Top1 inhibitor 1

    Catalog No. A13304
    Quick View
    human topoisomerase I (Top1) inhibitor
    Top1 inhibitor 1 (compound 28) is a potent human topoisomerase I (Top1) inhibitor with an IC50 value of 29 nM. 了解更多
  49. Voxilaprevir

    Catalog No. A12067
    Quick View
    HCV NS 3/4A protease inhibitor
    Voxilaprevir (GS-9857) is a fluorinated macrocyclic hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor with potent in vitro antiviral activity against genotypes 1-6 HCV and broad coverage of NS3/4A protease polymorphisms. GS-9857 improves coverage against commonly encountered NS3 resistance-associated variants (RAVs). 了解更多
  50. GS-626510

    Catalog No. A13305
    Quick View
    BET family bromodomains inhibitor
    GS-626510 is a potent, and orally bioavailable BET family bromodomains inhibitor, with Kd values of 0.59-3.2 nM for BRD2/3/4, with IC50 values of 83 nM and 78 nM foe BD1 and BD2, respectively. 了解更多

产品 201 到 250 共 520个

每页
页面:
  1. 3
  2. 4
  3. 5
  4. 6
  5. 7

设置降序顺序
Rewards