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产品 51 到 100 共 667个

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  1. Ezatiostat hydrochloride

    Catalog No. A21222
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    glutathione analog inhibitor
    Ezatiostat hydrochloride (TER199;TLK199 hydrochloride) is a glutathione analog inhibitor of glutathione S-transferase P1-1 (GSTP1-1). 了解更多
  2. Diclofensine hydrochloride

    Catalog No. A20923
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    monoamine reuptake inhibitor
    Diclofensine hydrochloride (Ro-8-4650 hydrochloride) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively. 了解更多
  3. Efonidipine hydrochloride monoethanolate

    Catalog No. A18030
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    dual T-type and L-type calcium channel blocker
    Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB). 了解更多
  4. Niraparib hydrochloride

    Catalog No. A18018
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    PARP1 and PARP2 inhibitor
    Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. 了解更多
  5. Landiolol hydrochloride

    Catalog No. A17675
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    adrenoceptor antagonist
    Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity?=?255:1, a half-life of 4?min)?? acts as an adrenoceptor antagonist. 了解更多
  6. NPS-2143 hydrochloride

    Catalog No. A11505
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    CaSR antagonist
    NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. 了解更多
  7. Ziprasidone hydrochloride monohydrate

    Catalog No. A11008
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    5-HT (serotonin) and dopamine receptor antagonist
    Ziprasidone hydrochloride monohydrate (CP 88059 hydrochloride monohydrate) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多
  8. PRX933 hydrochloride

    Catalog No. A12261
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    5-HT2c receptor agonist
    PRX933 hydrochloride is a 5-HT2c receptor agonist extracted from patent WO 2014140631 A1. 了解更多
  9. Vilazodone Hydrochloride

    Catalog No. A11604
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    serotonin transporter (SER) inhibitor
    Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist. 了解更多
  10. CSRM617 Hydrochloride

    Catalog No. A18438
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    OC2 inhibitor
    CSRM617 Hydrochloride is an inhibitor of the transcription factor ONECUT2 (OC2), thereby suppressing metastasis in mice. 了解更多
  11. Nylidrin Hydrochloride

    Catalog No. A17947
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    beta-adrenergic agonist
    Nylidrin hydrochloride is a beta-adrenergic agonist. Nylidrin hydrochloride is shown to be an effective inhibitor of IgE-mediated release of histamine from human basophils, and thus can be used as antiallergic agent. 了解更多
  12. Promazine hydrochloride

    Catalog No. A17638
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    D2DR inhibitor
    Promazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多
  13. Piperoxan hydrochloride

    Catalog No. A18336
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    α2 adrenoceptor antagonist
    Piperoxan hydrochloride is an α2 adrenoceptor antagonist. 了解更多
  14. Resminostat hydrochloride

    Catalog No. A15220
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    HDAC 抑制剂
    Resminostat hydrochloride是HDAC1/3/6的有效抑制剂(IC50 = 43-72 nM);对HDAC8的效力较低,IC50为877 nM。 了解更多
  15. Dasatinib hydrochloride

    Catalog No. A15060
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    Src 抑制剂
    Dasatinib hydrochloride是一种有效的Abl/Src双重抑制剂,IC50分别<1 nM/0.8 nM。还可以抑制c-Kit(WT/c-Kit(D816V),IC50为79 nM/37 nM。有效,选择性Raf激酶抑制剂能够抑制野生型B-Raf,B-RafV600E和c -Raf的IC50值分别为3.2、0.8和5.0 nM。 了解更多
  16. Tomatidine hydrochloride

    Catalog No. A22284
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    anti-inflammatory agent
    Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans. 了解更多
  17. PF-562271 hydrochloride

    Catalog No. A22370
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    FAK and Pyk2 kinase inhibitor
    PF-562271 hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively. 了解更多
  18. Miransertib hydrochloride

    Catalog No. A22376
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    Akt inhibitor
    Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. 了解更多
  19. GPNA hydrochloride

    Catalog No. A22452
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    glutamine transporter ASCT2 inhibitor
    GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. 了解更多
  20. M8-B (hydrochloride)

    Catalog No. A22607
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    TRPM8 antagonist
    M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Item No. 10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively). 了解更多
  21. YM 298198 Hydrochloride

    Catalog No. A22630
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    mGlu1 receptorsant agonist
    YM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM). 了解更多
  22. Thiamine hydrochloride

    Catalog No. A15710
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    micronutrient
    Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes. 了解更多
  23. Nortriptyline hydrochloride

    Catalog No. A17290
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    tricyclic antidepressant
    Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression. 了解更多
  24. Trilaciclib hydrochloride

    Catalog No. A22034
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    CDK4/6 inhibitor
    Trilaciclib hydrochloride is a CDK4/6 inhibitor with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. 了解更多
  25. (+)-Dihydrexidine hydrochloride

    Catalog No. A20339
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    dopamine D1 receptor agonist
    (+)-Dihydrexidine hydrochloride ((+)-DAR-0100 hydrochloride) is a dopamine D1 receptor agonist with an EC50 of 72± 21 nM. 了解更多
  26. Pargolol hydrochloride

    Catalog No. A20035
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    β adrenergic receptor antagonist
    Pargolol hydrochloride is a β adrenergic receptor antagonist. 了解更多
  27. ReN-1869 hydrochloride

    Catalog No. A19610
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    histamine H1 receptor antagonist
    ReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0.19±0.04 μM and the non-selective ?? site (guinea pig brain) with Ki of 0.45 μM. 了解更多
  28. Amibegron hydrochloride

    Catalog No. A19549
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    β3-adrenoceptor agonist
    Amibegron hydrochloride is a selective β3-adrenoceptor agonist, with an EC50 of 3.5 nM for β-adrenoceptor in rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity. 了解更多
  29. Epertinib hydrochloride

    Catalog No. A21950
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    EGFR, HER2 and HER4 inhibitor
    Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity. 了解更多
  30. SB-269970 hydrochloride

    Catalog No. A21889
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    5-HT7 receptor antagonist
    SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors. 了解更多
  31. MW-150 hydrochloride

    Catalog No. A21854
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    p38α MAPK inhibitor
    MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. 了解更多
  32. Cinaciguat hydrochloride

    Catalog No. A21838
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    guanylate cyclase (GC) activator
    Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets. 了解更多
  33. S55746 hydrochloride

    Catalog No. A21811
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    BCL-2 inhibitor
    S55746 hydrochloride (BLC201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. 了解更多
  34. Alpelisib hydrochloride

    Catalog No. A21794
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    PI3Kα inhibitor
    Alpelisib hydrochloride (BYL-719 hydrochloride) is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively. 了解更多
  35. 1-Naphthyl PP1 hydrochloride

    Catalog No. A21790
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    Src/c-Abl inhibitor
    1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). 了解更多
  36. Kira8 Hydrochloride

    Catalog No. A21780
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    IRE1α inhibitor
    Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. 了解更多
  37. Pomalidomide-C2-NH2 hydrochloride

    Catalog No. A21768
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    E3 ligase ligand-linker conjugate
    Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
  38. cIAP1 Ligand-Linker Conjugates 15 hydrochloride

    Catalog No. A21758
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    E3 ligase ligand-linker conjugate
    cIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs. 了解更多
  39. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride

    Catalog No. A21753
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    E3 ligase ligand-linker conjugate
    cIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs. 了解更多
  40. Pipequaline hydrochloride

    Catalog No. A21712
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    partial benzodiazepine receptor agonist
    Pipequaline hydrochloride (PK-8165 hydrochloride) is a partial benzodiazepine receptor agonist with anxiolytic activity. 了解更多
  41. JNJ-47117096 hydrochloride

    Catalog No. A21542
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    MELK inhibitor
    JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM. 了解更多
  42. Givinostat hydrochloride

    Catalog No. A21487
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    HDAC inhibitor
    Givinostat hydrochloride (ITF-2357 hydrochloride) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. 了解更多
  43. Camicinal hydrochloride

    Catalog No. A21415
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    motilin receptor agonist
    Camicinal hydrochloride (GSK962040 hydrochloride) is a small molecule, selective motilin receptor agonist with pEC50 of 7.9. 了解更多
  44. Saterinone hydrochloride

    Catalog No. A21402
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    PDE3 inhibitor
    Saterinone hydrochloride is a phosphodiesterase III (PDE III) inhibitor. 了解更多
  45. PHA-767491 hydrochloride

    Catalog No. A21395
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    dual Cdc7/Cdk9 inhibitor
    PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively. 了解更多
  46. Forodesine hydrochloride

    Catalog No. A20908
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    PNP inhibitor
    Forodesine hydrochloride (BCX-1777) is a highly potent and specific purine nucleoside phosphorylase (PNP) inhibitor. 了解更多
  47. Quinagolide hydrochloride

    Catalog No. A18038
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    dopamine D2 receptor agonist
    Quinagolide hydrochloride is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor. 了解更多
  48. Pirarubicin Hydrochloride

    Catalog No. A18037
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    topoisomerase II inhibitor
    Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors. 了解更多
  49. Cytarabine hydrochloride

    Catalog No. A17692
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    nucleoside analog
    Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. 了解更多
  50. MT-7716 hydrochloride

    Catalog No. A20004
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    NOP agonist
    MT-7716 hydrochloride (W-212393 hydrochloride) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention. 了解更多

产品 51 到 100 共 667个

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