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￥ 0.00 “Akt Inhibitor”的搜索结果
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PI3k-delta inhibitor 1
Catalog No. A14109 -
K-Ras(G12C) inhibitor 6
Catalog No. A14103 K-Ras(G12C) 抑制剂K-Ras(G12C) inhibitor 6 是致癌性K-Ras（G12C）的不可逆抑制剂，颠覆了天然核苷酸的偏爱性，使GDP优于GTP。 了解更多 -
NSC 42834(JAK2 Inhibitor V, Z3)
Catalog No. A14132 -
HPGDS inhibitor 1
Catalog No. A12258 -
MDM2 Inhibitor
Catalog No. A13582 -
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最新产品
AMG-510 (Sotorasib)
Catalog No. A19021 KRAS G12C covalent inhibitorAMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity. 了解更多 -
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MM-102 TFA
Catalog No. A21941 WDR5/MLL interaction inhibitorMM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide. 了解更多 -
gamma-Secretase Modulators
Catalog No. A11426 Amyloid-β production inhibitorgamma-Secretase Modulators (Amyloid-β production inhibitor) is a Amyloid-β production inhibitor. gamma-Secretase Modulators is useful for Alzheimer's disease. 了解更多 -
SID 3712249
Catalog No. A12286 miR-544 inhibitorSID 3712249 (MiR-544 Inhibitor 1) is an inhibitor of the biogenesis of microRNA-544 (miR-544). 了解更多 -
Collagen proline hydroxylase inhibitor-1
Catalog No. A11370 Collagen proline hydroxylase inhibitor-1 is an antifibroproliferative agents. 了解更多 -
Microtubule inhibitor 1
Catalog No. A18707 Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity, with an IC50 value of 9-16 nM in cancer cells. 了解更多 -
Mcl1-IN-2
Catalog No. A18366 -
IRAK inhibitor 6 (IRAK-IN-6)
Catalog No. A11460 IRAK 抑制剂IRAK-IN-6，也称为IRAK抑制剂6，是白介素1受体相关激酶4（IRAK-4）抑制剂。 据报道，IRAK-4对于激活包括NF-kB和MAPK途径在内的细胞内信号级联反应至关重要，这对于炎症细胞因子的产生至关重要。 了解更多 -
PDK1 inhibitor
Catalog No. A11528 -
IKK-3 Inhibitor
Catalog No. A11463 -
PI4KIII beta inhibitor 3
Catalog No. A15430 -
NFAT Inhibitor
Catalog No. A15381 NFAT 抑制剂NFAT Inhibitor是钙调神经磷酸酶介导的活化T细胞核因子（NFAT）的去磷酸化的选择性抑制剂。 了解更多 -
PIM-1 Inhibitor 2
Catalog No. A15368 -
Bax inhibitor peptide, negative control
Catalog No. A15338 -
p53 and MDM2 proteins-interaction-inhibitor chiral
Catalog No. A15201 -
c-FMS inhibitor
Catalog No. A15043 -
PKR Inhibitor
Catalog No. A13538 PKR 抑制剂PKR Inhibitor是一种羟吲哚/咪唑衍生物，可与PKR的ATP结合位点结合并阻断自磷酸化，IC50值为186-210nM。3PKR抑制剂可保护人类神经母细胞瘤细胞免受衣霉素介导的内质网应激触发的细胞损伤。 了解更多 -
Bcl-2 Inhibitor
Catalog No. A13580 Bcl-2 抑制剂Bcl-2 Inhibitor包含两种互变异构体的混合物。一种有效的，细胞可渗透的Bcl-2抑制剂与Bak BH3肽竞争体外结合Bcl-2和Bcl-XL的作用（分别为IC50 = 10 uM和7 uM）。 了解更多 -
STAT5 Inhibitor
Catalog No. A13628 STAT 抑制剂STAT5抑制剂是一种细胞可渗透的非肽烟酰yl，可通过靶向其SH2结构域（针对STAT5βSH2结构域EPO肽结合活性的IC50 = 47μM）来抑制STAT5。 了解更多 -
Collagen proline hydroxylase inhibitor
Catalog No. A11371 -
FABP4 Inhibitor
Catalog No. A13404 FABP4 Inhibitor是一种细胞可渗透的联苯唑氧乙酸酯，通过靶向其脂肪酸结合口袋(在使用1，8-氨基水杨酸的竞争性结合试验中Ki = < 2 nM)，作为脂肪细胞脂肪酸结合蛋白(aFABP/aP2)的有效和选择性抑制剂，同时对肌肉和表皮FABP氏病表现出低得多的亲和力(Ki分别为250 nM和350 nM)。 了解更多 -
Lavendustin B
Catalog No. A22298 GLUT1 inhibitorLavendustin B is an inhibitor of HIV-1 integrase interaction with LEDGF/p75 with an IC50 of 94.07 μM. Lavendustin B is an ATP-competitive GLUT1 inhibitor with a Ki of 15 ?M. Lavendustin B is also a weak inhibitor of tyrosine kinases. 了解更多 -
GSK1940029
Catalog No. A20820 SCD inhibitorGSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor extracted from patent WO/2009060053 A1, compound example 16. 了解更多 -
PTP1B-IN-1
Catalog No. A22000 PTP1B inhibitorPTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis. 了解更多 -
(R)-MG-132
Catalog No. A21980 proteasome inhibitor(R)-MG-132 ((S,R,S)-(-)-MG-132) is the enantiomer of MG-132. (R)-MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132. 了解更多 -
Zidebactam sodium salt
Catalog No. A21896 β-lactamase inhibitorZidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. 了解更多 -
Liarozole dihydrochloride
Catalog No. A21853 CYP450 dependent inhibitorLiarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase). 了解更多 -
AZD3839 free base
Catalog No. A21606 BACE1 inhibitorAZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor. 了解更多 -
IACS-8968 S-enantiomer
Catalog No. A21559 dual IDO/TDO inhibitorIACS-8968 (S-enantiomer) is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. 了解更多 -
IACS-8968 R-enantiomer
Catalog No. A21555 dual IDO/TDO inhibitorIACS-8968 (R-enantiomer) is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. 了解更多 -
Compound E
Catalog No. A21292 -
BMS-906024
Catalog No. A21172 gamma secretase inhibitorBMS-906024 is an oral and selective gamma secretase inhibitor (GSI) that is a small molecule Notch inhibitor. 了解更多
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