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￥ 0.00 “jwh 249”的搜索结果
36 个项目
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Cyclopamine
Catalog No. A10249 Hedgehog signaling 抑制剂Cyclopamine是一种特异性的Hedgehog (Hh)信号通路拮抗剂，作用于Smoothened (Smo)，IC50为46 nM。Cyclopamine 抑制Hedgehog信号通路， IC50 为46 nM。 了解更多 -
NVP-BSK805
Catalog No. A11193 JAK 抑制剂NVP-BSK805是喹喔啉JAK2抑制剂对红细胞增多症的有效和选择性抑制，喹喔啉JAK2抑制剂可有效抑制小鼠和大鼠中重组人促红细胞生成素诱导的红细胞增多症和髓外红细胞生成。IC50为0.5 nM，比作用于JAK1， JAK3和TYK2选择性高20倍以上。 了解更多 -
Pirarubicin
Catalog No. A10735 Topoisomerase II 抑制剂Pirarubicin是蒽环类抗肿瘤阿霉素的类似物。插入DNA中并与Topo II（拓扑异构酶II）相互作用并抑制DNA复制。 了解更多 -
SH-4-54
Catalog No. A14249 -
TNP-470
Catalog No. A14014 -
CEP-32496 hydrochloride
Catalog No. A15040 Raf 抑制剂CEP-32496 hydrochloride是野生型BRAF，V600E突变型BRAF和c-Raf的高效抑制剂，Kd值分别为14 nM，36 nM和39 nM。 了解更多 -
NFAT Inhibitor
Catalog No. A15381 NFAT 抑制剂NFAT Inhibitor是钙调神经磷酸酶介导的活化T细胞核因子（NFAT）的去磷酸化的选择性抑制剂。 了解更多 -
AMG 548
Catalog No. A10970 -
FLT3-IN-1
Catalog No. A16249 -
Azacosterol
Catalog No. A13295 -
Nedisertib
Catalog No. A17055 DNA-PK 抑制剂Nedisertib (M-3814,MSC2490484A)是一种可口服的DNA依赖性蛋白激酶（DNA-PK）抑制剂，具有潜在的抗肿瘤和化学/放射增敏活性。 了解更多 -
Syncytial Virus Inhibitor-1
Catalog No. A19053 RSV fusion inhibitorSyncytial Virus Inhibitor-1 is a potent, orally bioavailable respiratory syncytial virus (RSV) fusion inhibitor with EC50s of 0.002 μM, 0.004 μM, and 0.002 μM for RSV Long, RSV A2, and RSV B strains, respectively. 了解更多 -
PROTAC MDM2 Degrader-2
Catalog No. A18890 MDM2 inhibitorPROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. 了解更多 -
PROTAC MDM2 Degrader-4
Catalog No. A18877 MDM2 inhibitorPROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase. 了解更多 -
MD2-TLR4-IN-1
Catalog No. A18452 MD2-TLR4 inhibitorMD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多 -
SID 3712249
Catalog No. A12286 miR-544 inhibitorSID 3712249 (MiR-544 Inhibitor 1) is an inhibitor of the biogenesis of microRNA-544 (miR-544). 了解更多 -
Norverapamil hydrochloride
Catalog No. A12249 P-gp inhibitorNorverapamil hydrochloride ((??)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. 了解更多 -
BCR-ABL-IN-1
Catalog No. A12496 BCR-ABL inhibitorBCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia. 了解更多 -
DprE1-IN-2
Catalog No. A12495 DprE1 inhibitorDprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect. 了解更多 -
Avibactam sodium
Catalog No. A17306 non-β-lactam β-lactamase inhibitorAvibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively. 了解更多 -
(R)-Zanubrutinib
Catalog No. A21342 BTK inhibitor(R)-Zanubrutinib is the R enantiomer of Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (BTK) inhibitor. 了解更多 -
Sch-42495 racemate
Catalog No. A21408 NEP inhibitorSch-42495 racemate is the racemate of Sch-42495. Sch-42495 is a novel neutral metalloendopeptidase (NEP) inhibitor. Sch-42495 is the orally active ethylester prodrug of SCH 42354. 了解更多
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