“angiotensin converting enzyme ace”的搜索结果

产品 51 到 100 共 857个

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  1. Captopril

    Catalog No. A11738
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    Captopril是一种血管紧张素转换酶(ACE)抑制剂,用于治疗高血压和某些类型的充血性心力衰竭。 了解更多
  2. Benazepril HCl

    Catalog No. A10123
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    RAAS 抑制剂
    Benazepril hydrochloride是一种非肽血管紧张素转化酶(ACE)抑制剂。降低自发性高血压大鼠的血压和心肌肥大。 了解更多
  3. Elisartan

    Catalog No. A20697
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    Elisartan is an orally active non-peptide pro-drug of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities. 了解更多
  4. ZD 7155 hydrochloride

    Catalog No. A19959
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    AT1 receptor antagonist
    ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist. 了解更多
  5. Olodanrigan

    Catalog No. A21691
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    AT2R antagonist
    Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. 了解更多
  6. Dihexa

    Catalog No. A20933
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    Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. 了解更多
  7. TD-0212

    Catalog No. A13715
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    neprilysin (NEP) inhibitor
    TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP. 了解更多
  8. Apelin agonist 1

    Catalog No. A19035
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    apelin agonist
    Apelin agonist 1 is an oral selective apelin agonist AM-2995, a agonist of the APJ (APLNR, angiotensin receptor like-1) receptor, may be used in the treatment of cardiovascular conditions. 了解更多
  9. Azilsartan Medoxomil

    Catalog No. A16420
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    angiotensin II receptor type 1 拮抗剂
    Azilsartan medoxomil是一种口服给药的1型血管紧张素II受体拮抗剂,IC50为0.62 nM。 了解更多
  10. BIBS39

    Catalog No. A14154
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    angiotensin II receptor 拮抗剂
    BIBS39是一种非肽血管紧张素II(AII)受体拮抗剂,可从其特异性结合位点置换[125I] AII,其AII亚型(AT1)受体和K(i)的K(i)值为29+/-7 nM。)AII亚型2(AT2)受体的480+/-110 nM)值。 了解更多
  11. LCZ696 (Valsartan)

    Catalog No. A14206
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    angiotensin receptor-neprilysin 抑制剂
    LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂(ARNi),用于治疗高血压和心力衰竭。 了解更多
  12. Tasosartan

    Catalog No. A10891
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    Angiotensin II receptor 拮抗剂
    Tasosartan是一种血管紧张素II受体拮抗剂。 了解更多
  13. PD 123319 ditrifluoroacetate

    Catalog No. A13201
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    angiotensin AT2 receptor 拮抗剂
    PD 123319 ditrifluoroacetate是一种有效的,选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。 了解更多
  14. Fluxapyroxad

    Catalog No. A22073
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    the succinate dehydrogenase (SQR) enzyme inhibitor
    Fluxapyroxad, a broad-spectrum fungicide, is an inhibitor of the succinate dehydrogenase (SQR) enzyme. 了解更多
  15. TAS4464 hydrochloride

    Catalog No. A21708
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    NEDD8 activating enzyme inhibitor
    TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM. 了解更多
  16. C527

    Catalog No. A21365
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    pan DUB enzyme inhibitor
    C527 is a is a pan DUB enzyme inhibitor, with a high potency for the USP1/UAF1 complex (IC50=0.88 μM). 了解更多
  17. CC0651

    Catalog No. A21188
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    Cdc34 ubiquitin-conjugating enzyme inhibitor
    CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27Kip1, as confirmed by dose-response analysis. 了解更多
  18. MUT056399

    Catalog No. A21084
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    FabI enzyme inhibitor
    MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively. 了解更多
  19. Bergaptol

    Catalog No. A12303
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    CYP3A4 enzyme inhibitor
    Bergaptol is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. Recent studies suggest that it may have antiproliferative and anticancer properties. 了解更多
  20. Vanin-1-IN-1

    Catalog No. A19095
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    Vanin-1 enzyme inhibitor
    Vanin-1-IN-1 is an inhibitor of vanin-1 enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation. 了解更多
  21. PKAkt1/PKBa Human, Inactive enzyme Human Recombinant

    Catalog No. AP4564
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    Protein Kinase Akt1/PKB alpha, Inactive enzyme Human Recombinant 了解更多
  22. PKAkt1/PKBa, active enzyme Human Recombinant

    Catalog No. AP4563
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    Protein Kinase Akt1/PKB alpha, Active enzyme Human Recombinant 了解更多
  23. Adenosine deaminase

    Catalog No. A19330
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    Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. 了解更多
  24. Hyaluronidase

    Catalog No. A18232
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    local anesthetic additive
    Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive. 了解更多
  25. Cinnamylamine

    Catalog No. A20835
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    Cinnamylamine can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. 了解更多
  26. ASLAN003

    Catalog No. A22140
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    Dihydroorotate Dehydrogenase (DHODH) inhibitor
    ASLAN003 is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. 了解更多
  27. Conoidin A

    Catalog No. A22167
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    cell permeable inhibitor
    Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII). 了解更多
  28. ML266

    Catalog No. A22251
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    activator of glucocerebrosidase (GCase)
    ML266 (CID-46943215) is a activator of glucocerebrosidase (GCase) that does not inhibit the enzyme??s action but can still facilitates its translocation to the lysosome. 了解更多
  29. UK-371804 HCl

    Catalog No. A22379
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    uPA inhibitor
    UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin). 了解更多
  30. ODQ

    Catalog No. A22420
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    soluble guanylyl cyclase inhibitor
    ODQ is a potent and selective soluble guanylyl cyclase (sGC, nitric oxide-activated enzyme) inhibitor. ODQ enhances the pro-apoptotic effects of Cisplatin in human mesothelioma cells. 了解更多
  31. GPNA hydrochloride

    Catalog No. A22452
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    glutamine transporter ASCT2 inhibitor
    GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. 了解更多
  32. Soticlestat

    Catalog No. A22516
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    Soticlestat, also known as TAK 935 and OV935, is an inhibitor of the enzyme cholesterol 24-hydroxylase (CH24H). 了解更多
  33. Atabecestat

    Catalog No. A22605
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    BACE1 inhibitor
    Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. 了解更多
  34. Methotrexate disodium

    Catalog No. A17943
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    antifolate agent
    Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia). 了解更多
  35. α-Lipoic Acid

    Catalog No. A17341
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    antioxidant
    α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. 了解更多
  36. Iberin

    Catalog No. A20509
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    Iberin is a sulforaphane homolog and antioxidant. It induces phase II enzyme activity and suppresses CDK expression, inducing apoptosis in cancer cells. 了解更多
  37. mPGES1-IN-3

    Catalog No. A20454
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    mPGES-1 inhibitor
    mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor, which exhibits excellent mPGES-1 enzyme (IC50: 8 nM), cell (A549 IC50: 16.24 nM) and human whole blood potency (IC50: 249.9 nM). 了解更多
  38. Revizinone

    Catalog No. A20398
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    PDE inhibitor
    Revizinone is a novel selective phosphodiesterase (PDE) inhibitor with IC50 values on this enzyme to 0.036 microM. 了解更多
  39. TAK-243

    Catalog No. A20369
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    UAE (UBA1) inhibitor
    TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. 了解更多
  40. Roflumilast Impurity E

    Catalog No. A20365
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    PDE-4 inhibitor
    Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM. 了解更多
  41. 9-Propenyladenine

    Catalog No. A20357
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    9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase inhibitors, which block reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. 了解更多
  42. LX2343

    Catalog No. A20288
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    BACE1 inhibitor
    LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. 了解更多
  43. Asp-AMS

    Catalog No. A20271
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    aspartyl-tRNA synthetase inhibitor
    Asp-AMS, an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme. 了解更多
  44. ODM-204

    Catalog No. A20025
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    androgen receptor/CYP17A1 dual inhibitor
    ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme, with IC50s of 80?nM and 22 nM, respectively. 了解更多
  45. GSK180

    Catalog No. A19923
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    KMO inhibitor
    GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. 了解更多
  46. RR-11a

    Catalog No. A19852
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    Legumain inhibitor
    RR-11a is a synthetic enzyme inhibitor of Legumain. 了解更多
  47. UbcH5c-IN-1

    Catalog No. A19784
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    UbcH5c inhibitor
    UbcH5c-IN-1 (compound 6d) is a potent and selective small-molecule inhibitor of Ubiquitin-conjugating enzyme UbcH5c, with a Kd of 283 nM for E2 UbcH5c-IN-1 by covalent binding with Cys85. 了解更多
  48. H-Arg-4MβNA

    Catalog No. A19686
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    H-Arg-4MβNA is a substrate for cathepsin H, used for the detection of enzyme activity in gel electrophoresis. 了解更多
  49. BMS-816336

    Catalog No. A19528
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    11β-HSD1 inhibitor
    BMS-816336 is a novel, potent and orally bioavailable inhibitor against human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM. 了解更多
  50. Afabicin

    Catalog No. A19501
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    Afabicin (Debio 1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. 了解更多

产品 51 到 100 共 857个

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