微信关注
Total item
Cart Subtotal
￥ 0.00 GPCR / G Protein
-
Terfenadine
Catalog No. A17373 H1 histamine receptor antagonistTerfenadine ((??)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9 and induces p73, Noxa. 了解更多 -
Levocetirizine Dihydrochloride
Catalog No. A17440 L-isomer of cetirizine and histamine H1 receptor antagonistLevocetirizine dihydrochloride is a L-isomer of cetirizine and histamine H1 receptor antagonist. It incrases levels of CD4+ CD25+ T cells and decreases levels of eosinophils, decreasing allergy symptoms. 了解更多 -
Hydroxyzine pamoate
Catalog No. A17712 Histamine H1 receptor antagonistHydroxyzine pamoate is an histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. 了解更多 -
Diphenylpyraline hydrochloride
Catalog No. A17717 antihistamineDiphenylpyraline hydrochloride is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class. 了解更多 -
Acrivastine
Catalog No. A17746 Histamine 1 receptor antagonistAcrivastine (BW825C) is a short acting histamine 1 receptor antagonist for the treatment of allergic rhinitis. 了解更多 -
Mebhydrolin napadisylate
Catalog No. A17997 -
Mequitazine
Catalog No. A18206 Histamine H1 antagonistMequitazine is a potent histamine H1 antagonist or antihistamine. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. 了解更多 -
Nepicastat (free base) (SYN-117)
Catalog No. A10637 dopamine beta-hydroxylase 抑制剂Nepicastat (free base) (SYN-117)是多巴胺β-羟化酶的抑制剂，该酶催化多巴胺向去甲肾上腺素的转化。 了解更多 -
Nalmefene hydrochloride
Catalog No. A13843 dopamine receptor 激动剂Nalmefene hydrochloride是opioid receptor拮抗剂。 了解更多 -
Cariprazine hydrochloride
Catalog No. A15036 D3/D2 Dopamine Receptor 拮抗剂Cariprazine hydrochloride是一种新型的抗精神病药物，对多巴胺D3（Ki = 0.09 nM）和D2（Ki = 0.5 nM）受体具有高选择性和亲和力，对5-羟色胺5-HT（1A）受体具有中等亲和力。 了解更多 -
Metoclopramide
Catalog No. A15161 -
Phenylpiracetam
Catalog No. A15211 -
SKF38393 HCl
Catalog No. A15839 -
Loxapine Succinate
Catalog No. A17347 D2DR and D4DR inhibitorLoxapine Succinate is a D2DR and D4DR inhibitor and serotonergic receptor antagonist. Loxapine succinate is an antipsychotic agent used in schizophrenia. 了解更多 -
Promazine hydrochloride
Catalog No. A17638 D2DR inhibitorPromazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多 -
PF-06256142
Catalog No. A18872 D1 receptor agonistPF-06256142 is a potent and selective orthosteric agonist of the D1 receptor, with D1 EC50=30 nM and D1 binding Ki = 12 nM. 了解更多 -
Zamicastat
Catalog No. A13672 dopamine β-hydroxylase (DBH) inhibitorZamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor that could cross the blood-brain barrier (BBB) and cause central as well as peripheral effects. 了解更多 -
Veralipride
Catalog No. A13132 D2 receptor antagonistVeralipride is a D2 receptor antagonist. It is an alternative antidopaminergic treatment for menopausal symptoms. 了解更多 -
Pipamperone
Catalog No. A12621 D2 receptor antagonistPipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7). 了解更多 -
SPD-473 citrate
Catalog No. A12617 serotonin/dopamine/norepinephrine reuptake inhibitiorSPD-473 citrate is a serotonin/dopamine/norepinephrine reuptake inhibitior. 了解更多 -
Pentiapine
Catalog No. A12512 -
Trimethobenzamide hydrochloride
Catalog No. A17648 D2 receptor blockerTrimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. 了解更多 -
Quinagolide hydrochloride
Catalog No. A18038 dopamine D2 receptor agonistQuinagolide hydrochloride is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor. 了解更多 -
Haloperidol hydrochloride
Catalog No. A18304 dopamine D2 receptor antagonistHaloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic. 了解更多 -
SB-277011 dihydrochloride
Catalog No. A21353 dopamine D3 receptor antagonistSB-277011 dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively. 了解更多 -
Risperidone hydrochloride
Catalog No. A21458 dopamine D2 receptor antagonistRisperidone hydrochloride is a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist, with Kis of 0.16, 1.4 nM for 5-HT2 and D2 receptor, respectively. 了解更多 -
Risperidone mesylate
Catalog No. A21463 dopamine D2 receptor antagonistRisperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM). 了解更多 -
JNJ-37822681 dihydrochloride
Catalog No. A21470 dopamine D2 receptor antagonistJNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder. 了解更多 -
Pardoprunox hydrochloride
Catalog No. A21624 partial dopamine D2 and D3 receptor agonistPardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist. 了解更多 -
SKF-82958 hydrobromide
Catalog No. A21763 D1/D5 receptor full agonistSKF-82958 hydrobromide is a D1/D5 receptor full agonist. 了解更多 -
Vanoxerine
Catalog No. A21922 dopamine reuptake inhibitorVanoxerine (GBR-12909) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). 了解更多 -
Dihydrexidine
Catalog No. A21949 D1-like dopamine receptor (D1/D5) agonistDihydrexidine (DAR-0100) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist with an IC50 of 10 nM for D1 receptor. Dihydrexidine exhibits potent antiparkinsonian activity. 了解更多 -
Haloperidol D4
Catalog No. A21961 dopamine D2 receptor antagonistHaloperidol D4 is deuterium labeled haloperidol, and the latter is a potent dopamine D2 receptor antagonist. 了解更多 -
Haloperidol D4'
Catalog No. A21971 dopamine D2 receptor antagonistHaloperidol D4' is deuterium labeled haloperidol, and the latter is a potent dopamine D2 receptor antagonist. 了解更多 -
Ro 10-5824 dihydrochloride
Catalog No. A21986 dopamine D4 receptor partial agonistRo 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with Ki of 5.2 nM. 了解更多 -
Amisulpride hydrochloride
Catalog No. A21994 dopamine D2/D3 receptor antagonistAmisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively. 了解更多 -
Radafaxine hydrochloride
Catalog No. A20951 dopamine transporter/norepinephrine transportertransporters inhibitorRadafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. 了解更多 -
Cariprazine
Catalog No. A21202 D3 receptor and D2 receptor partial agonistCariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). 了解更多 -
Amisulpride
Catalog No. A10067 -
U 95666E
Catalog No. A10956 -
Rotigotine HCl
Catalog No. A11118 Dopamine Receptor 激动剂Rotigotine hydrochloride是一种多巴胺D2和D3受体激动剂。D2和D3的Ki值分别为13和0.71 nM。 了解更多 -
Adoprazine (SLV313)
Catalog No. A11297 -
Chlorprothixene
Catalog No. A10207 Chlorprothixene对下列受体具有强烈的拮抗作用：5-HT2，D1，D2，D3，H1，mACh，α1-肾上腺素。 了解更多 -
Thioridazine hydrochloride
Catalog No. A11119 Thioridazine hydrochloride是一种多巴胺受体拮抗剂，具有抗精神病活性。 最近还报道了硫代哒嗪能够成功杀死人类癌症干细胞。 了解更多 -
Vanoxerine 2HCl (GBR-12909)
Catalog No. A10725 dopamine re-uptake 抑制剂Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物，是一种有效的、选择性的多巴胺摄取（dopamine uptake）抑制剂。 了解更多
FILTER BY:
购物选项
- 分类
-
- 5-HT Receptors (143)
- Adrenergic Receptors (110)
- Histamine Receptors (62)
- Opioid Receptors (28)
- Metabotropic glutamate receptors (mGluR) (50)
- Melatonin Receptors (4)
- Peptide Receptors (6)
- Smoothened Receptors (14)
- CXCR (30)
- G Protein (26)
- Platelet-Activating Factor (PAF) Receptors (10)
- Endothelin Receptors (21)
- LPA Receptor (13)
- Prostanoid Receptors (28)
- Adenosine Receptors (48)
- Cannabinoid Receptors (26)
- Neurotensin Receptors (4)
- Orexin Receptors (20)
- Somatostatin Receptors (3)
- Neurokinin Receptors (20)
- Protease-Activated Receptors (PAR) (2)
- S1P Receptor (21)
- CGRP Receptor (8)
- Sigma receptor (13)
- Guanylate Cyclase (8)
- cAMP (6)
- GHSR (5)
- Bombesin Receptors (1)
- Imidazoline Receptor (8)
- CCK (6)
- GLP-1 receptors (8)
- Calcium-Sensing Receptor (6)
- GPCR19 (5)
- CRFR (7)
- 作用机制
-
- Inhibitor (抑制剂) (86)
- Agonist (激动剂) (229)
- Antagonist (拮抗剂) (385)
- Activator (激活剂) (12)
- Modulator (调节剂) (28)
- Blocker (阻断剂) (12)
- Stabilizer (稳定剂) (1)
- Stimulator (刺激物) (4)
- 靶点
-
- A1 adenosine receptor (1)
- A3 adenosine receptor (1)
- Aurora A (1)
- Aurora B (1)
- Aurora C (1)
- COX-1 (1)
- COX-2 (1)
- CXCL12 (1)
- CXCL8 (2)
- CXCR1 (4)
- CXCR2 (9)
- CXCR4 (11)
- Histamine H1 receptor (1)
ADOOQ 产品质量保证
We promise all products to perform as described.