微信关注
China
Total item
Cart Subtotal
￥ 0.00 GPCR / G Protein
-
Verucerfont
Catalog No. A16950 CRF-1 拮抗剂Verucerfont，也称为GSK561679和NBI77860，是CRF-1拮抗剂。Verucerfont阻止CRH-1受体，因此减少了慢性应激后ACTH的释放。 了解更多 -
Emicerfont
Catalog No. A14047 -
Pexacerfont
Catalog No. A14105 CRF1 receptor antagonistPexacerfont is a selective corticotropin-releasing factor (CRF1) receptor antagonist with IC50 of 6.1??0.6 nM for human CRF1 receptor. 了解更多 -
NPS-2143 (SB-262470)
Catalog No. A11140 CaSR 拮抗剂NPS-2143 (SB-262470)是一种选择性的Ca2+感应受体拮抗剂，显示可阻止HEK293细胞中表达的人Ca2+受体引起的细胞质Ca2+浓度增加，IC50为43 nM。 了解更多 -
NPS-2143 hydrochloride
Catalog No. A11505 CaSR antagonistNPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. 了解更多 -
Loxiglumide (CR1505)
Catalog No. A11769 -
Proglumide sodium salt
Catalog No. A13713 CCK 拮抗剂Proglumide sodium salt是一种非选择性胆囊收缩素（CCK）拮抗剂。它抑制CCK刺激的淀粉酶分泌，并防止CCK诱导的小鼠胰腺腺泡中的2-脱氧葡萄糖摄取。 了解更多 -
Z-360 calcium salt (Nastorazepide calcium salt)
Catalog No. A13671 CCK-2 receptor 拮抗剂Z-360 calcium salt (Nastorazepide calcium salt)是一种选择性口服可口服的1,5-苯并二氮杂卓衍生物胃泌素/胆囊收缩素2（CCK-2）受体拮抗剂，具有潜在的抗肿瘤活性。 了解更多 -
Nastorazepide (Z-360)
Catalog No. A15984 CCK-2 receptor 拮抗剂Nastorazepide (Z-360) 是一种选择性的，口服的1,5-苯二氮杂卓衍生物胃泌素/胆囊收缩素2（CCK-2）受体拮抗剂，具有潜在的抗肿瘤活性。 了解更多 -
Proglumide
Catalog No. A18171 CCK antagonistProglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. IProglumide is a known cholecystokinin (CCK) antagonist. 了解更多 -
Dexloxiglumide
Catalog No. A18541 CCKA receptor antagonistDexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8). 了解更多 -
KU14R
Catalog No. A13987 -
GSK221149A (Retosiban)
Catalog No. A13106 Oxytocin Receptor 拮抗剂GSK221149A (Retosiban)是一种口服药物，可作为选择性纳摩尔（Ki = 0.65 nM）催产素受体拮抗剂，其选择性是相关血管加压素受体的> 1400倍。 了解更多 -
PF-3274167
Catalog No. A13754 -
L-371,257
Catalog No. A21219 oxytocin receptor antagonistL-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM). 了解更多 -
S1RA (E-52862)
Catalog No. A12504 sigma-1 receptor 拮抗剂S1RA是一种选择性sigma-1受体拮抗剂，据报道其结合亲和力为Ki = 17.0±7.0 nM，对sigma-2受体具有选择性，并且对其他170种受体，酶，转运蛋白和离子通道具有选择性。 了解更多 -
BD-1047 2HBr
Catalog No. A13196 -
Sigma-1 receptor antagonist 2
Catalog No. A18504 sigma 1 receptor antagonistSigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (??1 R) antagonist with Kis of 3.88 and 1288 nM for ??1 and ??2 receptor, respectively. 了解更多 -
Sigma-1 receptor antagonist 3
Catalog No. A18501 Sigma-1 receptor antagonistSigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (??1) receptor antagonist with a Ki of 1.14 nM. 了解更多 -
Vasopressin antagonist 1867
Catalog No. A16188 V1b receptor 拮抗剂Vasopressin antagonist 1867，可口服和选择性V1b受体拮抗剂（hV1b抑制作用的IC50值为3 nM，相对于hV1a，hV2和hOT表现出> 1000倍的选择性）。 了解更多 -
Mozavaptan
Catalog No. A16622 nonpeptide vasopressin V2 receptor antagonistMozavaptan (OPC31260) is a orally effective, nonpeptide vasopressin V2 receptor antagonist with an IC50 of 14 nM. 了解更多 -
Lixivaptan
Catalog No. A21279 vasopressin receptor V2 antagonistLixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively. 了解更多 -
MK 3207 HCl
Catalog No. A10598 CGRP Receptor 拮抗剂MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂，IC50为0.12 nM。 了解更多 -
MK-0974 (Telcagepant)
Catalog No. A11255 -
BMS-927711
Catalog No. A13102 CGRP receptor 拮抗剂BMS-927711是一种有效的，选择性的，竞争性的人降钙素基因相关肽（CGRP）受体拮抗剂，已显示出体内功效，而没有血管收缩作用。 了解更多 -
CGRP 8-37 (human)
Catalog No. A16949 CGRP receptor 拮抗剂CGRP 8-37 (human)是人降钙素基因相关肽（hCGRP）片段，也是CGRP受体的拮抗剂。序列：Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn- Val-Gly-Ser-Lys-Ala-Phe；VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF。 了解更多 -
Ubrogepant
Catalog No. A21670 CGRP antagonistUbrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine. 了解更多 -
Olcegepant hydrochloride
Catalog No. A21900 CGRP1 receptor antagonistOlcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. 了解更多 -
FTY720 (Fingolimod)
Catalog No. A10408 S1P Receptor 拮抗剂FTY720 (Fingolimod)是ISP-1(肉豆蔻酸)的衍生物，ISP-1是中国草药Iscaria sinclarii的真菌代谢物，也是鞘氨醇的结构类似物。 了解更多 -
Fingolimod
Catalog No. A17798 S1P antagonistFingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant. 了解更多 -
VPC 23019
Catalog No. A20102 S1P antagonistVPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively). 了解更多 -
Vorapaxar (SCH 530348)
Catalog No. A12832 PAR-1 拮抗剂Vorapaxar (SCH 530348)是一种有效的口服活性凝血酶受体（PAR-1）拮抗剂，Ki为8.1 nM。 了解更多 -
Aprepitant (MK-0869)
Catalog No. A10083 neurokinin-1 receptor 拮抗剂Aprepitant (MK-0869)被归类为NK1拮抗剂。已经显示，阿瑞匹坦通过阻止P物质降落在大脑神经元受体上，从而抑制细胞毒性化疗药物引起的急性呕吐和延迟呕吐。还显示出它能增加5-HT3受体拮抗剂恩丹西酮和皮质类固醇地塞米松的活性，它们也可用于预防化学疗法引起的恶心和呕吐。 了解更多 -
MK-0517 (Fosaprepitant)
Catalog No. A11756 neurokinin-1 receptor 拮抗剂MK-0517 (Fosaprepitant,L-758,298)是Aprepitant的水溶性磷酰基前药，它是NK1拮抗剂。 了解更多 -
Vofopitant (GR 205171)
Catalog No. A12793 -
GW679769 (Casopitant)
Catalog No. A13103 -
Ibodutant (MEN 15596)
Catalog No. A13104 tachykinin NK2 receptor 拮抗剂Ibodutant (MEN 15596)是速激肽NK2受体拮抗剂，pKi 值为10.1，用于治疗腹泻型肠易激综合症（IBS-D）。 了解更多
FILTER BY:
Filtering:
- 作用机制: Antagonist (拮抗剂) 删除该内容
购物选项
- 分类
-
- 5-HT Receptors (72)
- Adrenergic Receptors (28)
- Histamine Receptors (36)
- Opioid Receptors (10)
- Metabotropic glutamate receptors (mGluR) (15)
- Smoothened Receptors (4)
- CXCR (19)
- G Protein (5)
- Platelet-Activating Factor (PAF) Receptors (7)
- Endothelin Receptors (17)
- LPA Receptor (11)
- Prostanoid Receptors (14)
- Adenosine Receptors (27)
- Cannabinoid Receptors (8)
- Neurotensin Receptors (1)
- Orexin Receptors (18)
- Somatostatin Receptors (2)
- Neurokinin Receptors (19)
- Protease-Activated Receptors (PAR) (1)
- S1P Receptor (4)
- CGRP Receptor (7)
- Sigma receptor (5)
- cAMP (1)
- Imidazoline Receptor (2)
- CCK (6)
- Calcium-Sensing Receptor (2)
- GPCR19 (1)
- CRFR (7)
- 靶点
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
ADOOQ 产品质量保证
We promise all products to perform as described.