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￥ 0.00 “ab fubinaca”的搜索结果
40 个项目
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CP-640186 hydrochloride
Catalog No. A21808 ACC inhibitorCP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. 了解更多 -
VP3.15 dihydrobromide
Catalog No. A21789 PDE7/GSK3 inhibitorVP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. 了解更多 -
SHP099 hydrochloride
Catalog No. A21762 SHP2 inhibitorSHP099 hydrochloride is a potent, selective and orally available SHP2 inhibitor with an IC50 of 70 nM. 了解更多 -
BMS-654457
Catalog No. A21704 Factor XIa (FXIa) inhibitorBMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa), binding with human and rabbit FXIa with Kis of 0.2 and 0.42 nM, respectively. 了解更多 -
Rasagiline 13C3 mesylate racemic
Catalog No. A21350 Monoamine oxidase inhibitorRasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. 了解更多 -
Lazabemide
Catalog No. A21270 MAO-B inhibitorLazabemide(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). 了解更多 -
TVB-3664
Catalog No. A18829 FASN inhibitorTVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression. 了解更多 -
HSP27 inhibitor J2
Catalog No. A18874 HSP27 inhibitorHSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. 了解更多 -
2-Hydroxy atorvastatin calcium salt
Catalog No. A18971 HMG-CoA reductase inhibitor2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM. 了解更多 -
VP3.15
Catalog No. A18538 dual PDE7/GSK-3 inhibitorVP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). 了解更多 -
Edoxaban tosylate
Catalog No. A15076 -
Choline Fenofibrate
Catalog No. A15044 -
ABT-046
Catalog No. A14984 -
5-R-Rivaroxaban
Catalog No. A14979 Factor Xa 抑制剂5-R-Rivaroxaban是利伐沙班的（R）对映异构体。利伐沙班是一种新型的口服直接Xa因子抑制剂，在晚期开发中用于预防和治疗血栓栓塞性疾病。 了解更多 -
Edoxaban (tosylate Monohydrate)
Catalog No. A14317 Factor Xa 抑制剂Edoxaban (tosylate Monohydrate)是选择性Factor Xa抑制剂，Ki为0.561 nM。 了解更多 -
Betrixaban
Catalog No. A12518 FXa 抑制剂Betrixaban是一种抗凝血药，可作为直接Xa因子抑制剂。它具有强大的，口服活性和对因子Xa的高度选择性，由于其低hERG亲和力而从一组相似的化合物中选择。 了解更多 -
Letaxaban (TAK-442)
Catalog No. A12871 factor Xa 抑制剂Letaxaban (TAK-442)是一种有效的，选择性的，口服活性的Xa抑制剂，是一种四氢嘧啶-2（1H）-衍生物。TAK-442在贫血小板的人[半最大抑制浓度（IC（50））：53 nM，TAK-442]和大鼠（IC（50）：32 nM，TAK-442）血浆中抑制内源性FXa活性。 了解更多 -
Crisaborole (AN2728)
Catalog No. A12776 PDE4 抑制剂?AN2728是一种局部给药的含硼抗炎化合物，可抑制PDE4活性，从而抑制TNFalpha，IL-12，IL-23和其他细胞因子的释放。抑制PDE4的 IC50 值为0.49 μM。 了解更多 -
Otamixaban (FXV 673)
Catalog No. A11517 -
Clarithromycin
Catalog No. A10225 cytochrome P4503A4 抑制剂Clarithromycin是一种大环内酯类抗生素。它通过干扰细菌的蛋白质合成来防止细菌生长。 了解更多 -
Fludarabine (Fludara)
Catalog No. A10396 STAT 抑制剂Fludarabine或fludarabine(fludara)是一种用于治疗血液恶性肿瘤(血细胞癌，如白血病和淋巴瘤)的化疗药物。Fludarabine通过干扰核糖核苷酸还原酶和DNA聚合酶来抑制DNA合成。它对分裂细胞和静止细胞都有活性。 了解更多 -
Rivaroxaban (Xarelto)
Catalog No. A10800 Factor Xa 抑制剂Rivaroxaban (Xarelto)是一种Factor Xa的直接抑制剂，无细胞试验中Ki和IC50分别为0.4 nM和0.7 nM。 了解更多 -
Methotrexate (Abitrexate)
Catalog No. A10021 -
Abiraterone Acetate (CB7630)
Catalog No. A11058 -
Abiraterone (CB-7598)
Catalog No. A10020 -
Decitabine
Catalog No. A10292 DNA Methyltransferase 抑制剂Decitabine是一种次甲基化剂，它通过抑制DNA甲基转移酶来使DNA次甲基化。 了解更多 -
Apixaban (BMS-562247-01)
Catalog No. A10082 Factor Xa 抑制剂Apixaban (BMS-562247-01)是一种抗凝剂，用于预防静脉血栓栓塞和静脉血栓栓塞事件。 了解更多
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