“betaine hydrochloride”的搜索结果

23 个项目

每页

设置降序顺序
  1. Alectinib Hydrochloride

    Catalog No. A18000
    Quick View
    ALK inhibitor
    Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. 了解更多
  2. Defactinib hydrochloride

    Catalog No. A22003
    Quick View
    FAK inhibitor
    Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. 了解更多
  3. Btk inhibitor 1 R enantiomer hydrochloride

    Catalog No. A21865
    Quick View
    BTK inhibitor
    Btk inhibitor 1 R enantiomer hydrochloride (Ibrutinib analog hydrochloride) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs). 了解更多
  4. Ensartinib hydrochloride

    Catalog No. A21719
    Quick View
    ALK/MET inhibitor
    Ensartinib hydrochloride (X-396 hydrochloride) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. 了解更多
  5. Epertinib hydrochloride

    Catalog No. A21950
    Quick View
    EGFR, HER2 and HER4 inhibitor
    Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity. 了解更多
  6. 1-Naphthyl PP1 hydrochloride

    Catalog No. A21790
    Quick View
    Src/c-Abl inhibitor
    1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). 了解更多
  7. Vandetanib HCl

    Catalog No. A15271
    Quick View
    VEGFR 抑制剂
    Vandetanib hydrochloride是一种有效的VEGFR2抑制剂,IC50为40 nM。 了解更多
  8. Gefitinib hydrochloride

    Catalog No. A15093
    Quick View
    EGFR 抑制剂
    Gefitinib hydrochloride是一种EGFR抑制剂,可通过靶细胞中的表皮生长因子受体(EGFR)中断信号传导。因此,它仅在EGFR突变和过度活跃的癌症中有效。 了解更多
  9. TAK-659 hydrochloride

    Catalog No. A21885
    Quick View
    Syk inhibitor
    TAK-659 hydrochloride is a potent, selective and orally available spleen tyrosine kinase (Syk) inhibitor with an IC50 of 3.2 nM. 了解更多
  10. HS-10296 hydrochloride

    Catalog No. A21661
    Quick View
    EGFR/T790M inhibitor
    HS-10296 hydrochloride is an orally available and third-Generation inhibitor of epidermal growth factor receptor (EGFR)-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR. 了解更多
  11. Regorafenib Hydrochloride

    Catalog No. A11546
    Quick View
    VEGFR1/2/3/PDGFRβ/Kit/RET/Raf-1 inhibitor
    Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively. 了解更多
  12. Crizotinib hydrochloride

    Catalog No. A16245
    Quick View
    c-Met/NPM-ALK 抑制剂
    Crizotinib hydrochloride是c-Met激酶和NPM-ALK的抑制剂。 了解更多
  13. TG 100801 HCl

    Catalog No. A15261
    Quick View
    VEGFr2 抑制剂
    TG 100801 HCl是TG 100572(HY-10184)的前药,TG 100572是一种多靶点激酶抑制剂,可抑制选择性生长因子受体酪氨酸激酶和Src家族激酶,IC50值为2/7/2/1/0.5 nM或VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse分别。 了解更多
  14. TG 100572 HCl

    Catalog No. A15260
    Quick View
    VEGFR2/Src kinase 抑制剂
    TG 100572 HCl是一种多靶点激酶抑制剂,可抑制选择性生长因子受体酪氨酸激酶和Src家族激酶,分别对VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse的IC50值为2/7/2/1/0.5 nM。 了解更多
  15. Icotinib Hydrochloride

    Catalog No. A13718
    Quick View
    EGFR 抑制剂
    Icotinib hydrochloride是一种有效的特异性表皮生长因子受体(EGFR)酪氨酸激酶抑制剂(TKI),IC(50)为5 nM,包括EGFR(L858R),EGFR(L861Q),EGFR(T790M)和EGFR的突变体(T790M,L858R)。 了解更多
  16. ZM 323881 hydrochloride

    Catalog No. A11954
    Quick View
    VEGFR 抑制剂
    ZM 323881 hydrochloride是一种有效且选择性的人血管内皮生长因子受体2(VEGFR2/KDR)激酶活性抑制剂。 了解更多
  17. Canertinib dihydrochloride

    Catalog No. A11344
    Quick View
    EGFR inhibitor
    Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. 了解更多
  18. Nilotinib monohydrochloride monohydrate

    Catalog No. A15186
    Quick View
    Bcr-Abl 抑制剂
    Nilotinib monohydrochloride monohydrate是一种Bcr-Abl抑制剂,IC50小于30 nM。 了解更多
  19. LDK378 (Ceritinib) dihydrochloride

    Catalog No. A15142
    Quick View
    ALK 抑制剂
    LDK378 (Ceritinib) dihydrochloride是有效的抗ALK抑制剂,IC50为0.2 nM,对IGF-1R和InsR的选择性分别为40倍和35倍。 了解更多
  20. BAY 61-3606 dihydrochloride

    Catalog No. A15017
    Quick View
    Syk 抑制剂
    BAY 61-3606 dihydrochloride是一种有效的Syk激酶抑制剂(Ki = 7.5 nM)。 了解更多
  21. ZM 306416

    Catalog No. A11955
    Quick View
    VEGFR 抑制剂
    ZM 306416 hydrochloride是一种VEGF受体酪氨酸激酶抑制剂,可抑制KDR(IC50 = 100 nM)和Flt(IC50 = 2 uM)酪氨酸激酶。 了解更多
  22. Erlotinib HCl

    Catalog No. A10362
    Quick View
    EGFR 抑制剂
    Erlotinib hydrochloride是一种可逆的酪氨酸激酶抑制剂,作用于表皮生长因子受体(EGFR)。 了解更多
  23. Pazopanib HCl (GW786034)

    Catalog No. A10699
    Quick View
    VEGFR/PDGFR/FGFR 抑制剂
    Pazopanib HCl (GW786034)是VEGFR-1,VEGFR-2,VEGFR-3,PDGFR-a/β和c-kit的有效且选择性的多靶点酪氨酸激酶抑制剂,可阻止肿瘤生长并抑制血管生成。 了解更多

23 个项目

每页

设置降序顺序
Rewards