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Indirubin Derivative E804
Catalog No. A21052 IGF1R inhibitorE 804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R. 了解更多 -
Resatorvid
Catalog No. A11543 TLR4 inhibitorResatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor and plays pivotal role in various inflammatory diseases. 了解更多 -
IRAK inhibitor 4
Catalog No. A11458 IRAK4 inhibitorIRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4(IRAK4) inhibitor. 了解更多 -
EGFR-IN-3
Catalog No. A15847 -
GENZ-882706
Catalog No. A12484 CSF-1R InhibitorGENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor extracted from patent WO 2017015267A1. 了解更多 -
Lestaurtinib
Catalog No. A11274 multi-kinase inhibitorLestaurtinib (CEP-701;KT-5555) is a multi-kinase inhibitor with potent activity against the Trk family of receptor tyrosine kinases. Lestaurtinib inhibits JAK2, FLT3 and TrkA with IC50s of 0.9, 3 and less than 25 nM, respectively. 了解更多 -
CHMFL-EGFR-202
Catalog No. A12524 EGFR inhibitorCHMFL-EGFR-202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively. 了解更多 -
Vilazodone Hydrochloride
Catalog No. A11604 serotonin transporter (SER) inhibitorVilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist. 了解更多 -
TRPC6-IN-1
Catalog No. A12309 TRPC6 inhibitorTRPC6-IN-1 is a Transient Receptor Potential Canonical 6 Channel (TRPC6) inhibitor, with an EC50 of 4.66 μM. 了解更多 -
MD2-TLR4-IN-1
Catalog No. A18452 MD2-TLR4 inhibitorMD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多 -
c-Fms-IN-8
Catalog No. A18879 CSF-1R, c-FMS Type II inhibitorc-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM. 了解更多 -
c-Fms-IN-10
Catalog No. A19017 FMS inhibitorc-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, an kinase inhibitor of FMS (Colony stimulating factor-1 receptor, CSF-1R) with IC50 of 2 nM. c-Fms-IN-10 has anti-tumor activity. 了解更多 -
TGFβRI-IN-1
Catalog No. A18800 TGFβRI kinase inhibitorTGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively. 了解更多 -
L-(-)-α-Methyldopa (hydrate)
Catalog No. A18111 DOPA decarboxylase inhibitorMethyldopa Sesquihydrate is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. 了解更多 -
Molindone hydrochloride
Catalog No. A17647 MAO inhibitorMolindone HCl is a D2 dopamine receptor antagonist. It also acts as a MAO inhibitor. 了解更多 -
Dinoprost tromethamine
Catalog No. A17505 Prostaglandin Receptor inhibitorDinoprost Tromethamine, also known as Dinoprost Trometamol, is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. 了解更多 -
Benorylate
Catalog No. A17501 Prostaglandin Receptor inhibitorBenorilate, also known as Win-11450, is an ester of aspirin and paracetamol with analgesic, antipyretic, and anti-inflammatory activity used in the treatment of rheumatoid diseases. Benorilate has less severe side effects than aspirin. 了解更多 -
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最新产品
AG1295
Catalog No. A17227 -
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AX-024 hydrochloride
Catalog No. A18332 TNF receptor inhibitorAX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases. 了解更多 -
Loxapine Succinate
Catalog No. A17347 D2DR and D4DR inhibitorLoxapine Succinate is a D2DR and D4DR inhibitor and serotonergic receptor antagonist. Loxapine succinate is an antipsychotic agent used in schizophrenia. 了解更多 -
Importazole
Catalog No. A17128 nuclear transport receptor importin-β 抑制剂Importazole是Importin-β的细胞可渗透抑制剂。它可能通过改变与RanGTP的相互作用来特异性抑制importin-β的功能。 了解更多 -
Eucalyptol
Catalog No. A15662 -
Flopropione
Catalog No. A16550 5-HT1A receptor antagonist/COMT inhibitorFlopropione是5-HT1A受体拮抗剂，也是儿茶酚-邻甲基转移酶（COMT）抑制剂。 了解更多 -
LY 3200882
Catalog No. A16816 TGFβRI 抑制剂LY 3200882是有效的、高选择性TGF-β receptor type 1 (TGFβRI)抑制剂，在体外肿瘤组织和免疫细胞以及体内皮下肿瘤中，有效地以浓度依赖方式抑制TGFβ介导的SMAD磷酸化。 了解更多 -
Antazoline HCl
Catalog No. A16411 -
Reparixin L-lysine salt
Catalog No. A15219 CXCL8 receptor 抑制剂Reparixin L-lysine salt是CXCL8受体的抑制剂，也抑制CXCR1和CXCR2的活化，已显示在各种损伤模型中减弱了炎症反应。 了解更多 -
EGFR Inhibitor
Catalog No. A13673 EGFR 抑制剂EGFR inhibitor是一种可透过细胞的4,6-二取代嘧啶化合物，可选择性抑制EGFR激酶，在体外的IC50值为21 nM，可阻断细胞中的受体自身磷酸化。 了解更多 -
Atosiban
Catalog No. A14334
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