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Calcein Blue
Catalog No. A19780 blue-fluorescent dyeCalcein Blue is a short-term, blue-fluorescent dye for labeling live cells. 了解更多 -
PROTAC CRABP-II Degrader-2
Catalog No. A19773 CRABP-II degraderPROTAC CRABP-II Degrader-2 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
PROTAC CRABP-II Degrader-3
Catalog No. A19764 CRABP-II degraderPROTAC CRABP-II Degrader-3 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1. 了解更多 -
TRAF-STOP inhibitor 6877002
Catalog No. A19758 CD40-TRAF6 interaction inhibitorTRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction, compound VII, shows inhibition of NF-κB activation in RAW cells, extracted from patent WO2014033122A1. 了解更多 -
Real Thiol
Catalog No. A19652 fluorescent probeReal Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells. 了解更多 -
VU0529331
Catalog No. A19614 potassium channel (non-GIRK1/X) activatorVU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel (non-GIRK1/X) activator, with EC50s of 5.1 ?M and 5.2 ?M for GIRK2 and GIRK1/2 in HEK293 cells, respectively, also effective on GIRK4 homomeric channel. 了解更多 -
(S,R,S)-AHPC TFA
Catalog No. A19593 (S,R,S)-AHPC TFA (MDK7526 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA (MDK7526 TFA) can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells. 了解更多 -
D-Ala-Lys-AMCA
Catalog No. A19387 D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. 了解更多 -
Inarigivir soproxil
Catalog No. A19335 innate immunity agonistInarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. 了解更多 -
trans-Ned 19
Catalog No. A19327 NAADP antagonist and TPC blockertrans-Ned 19, a NAADP antagonist and TPC blocker, suppresses the calcium signal in human umbilical vein endothelial cells (HUVEC) and the rat aorta relaxation in response to low histamine concentrations. 了解更多 -
Praliciguat
Catalog No. A19315 guanylate cyclase stimulatorPraliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM. 了解更多 -
Epsilon-momfluorothrin
Catalog No. A19221 Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats. 了解更多 -
3'-Azido-3'-deoxy-5-methylcytidine
Catalog No. A19200 XMRV inhibitor3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 了解更多 -
HSV-TK substrate
Catalog No. A19149 HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. HSV-TK substrate shows antitumor activity. 了解更多 -
MitoTam bromide, hydrobromide
Catalog No. A19142 ETC inhibitorMitoTam bromide, hydrobromide is a tamoxifen derivative, an electron transport chain (ETC) inhibitor, spreduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology. 了解更多 -
Pyrindamycin B
Catalog No. A21420 Pyrindamycin B is an antibiotic, actives against gram-positive and gram-negative bacterias, and exhibits strong therapeutic effects against both drug-sensitive and resistant cells of P388 leukemia in mice. 了解更多 -
Ombrabulin hydrochloride
Catalog No. A21040 Ombrabulin hydrochloride is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells. 了解更多 -
G-418 disulfate
Catalog No. A21002 G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. 了解更多 -
Talarozole
Catalog No. A21124 retinoic acid metabolism blocking agentTalarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively. 了解更多 -
CHPG sodium salt
Catalog No. A21968 mGluR5 agonistCHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. 了解更多 -
ITI214 free base
Catalog No. A21947 picomolar PDE1 inhibitorITI-214 (free base) is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). 了解更多 -
Niraparib R-enantiomer
Catalog No. A21880 PARP1 inhibitorNiraparib R-enantiomer (MK-4827 R-enantiomer) is an excellent PARP1 inhibitor with IC50 of 2.4 nM. 了解更多 -
20(S)-Hydroxycholesterol
Catalog No. A21850 Smo allosteric activator20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells. 了解更多 -
Rusalatide acetate
Catalog No. A21791 regenerative peptideRusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. 了解更多 -
LY2365109 hydrochloride
Catalog No. A21779 GlyT1 inhibitorLY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a. 了解更多
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