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MLN4924 (HCL Salt)
Catalog No. A11499 -
p38-α MAPK-IN-1
Catalog No. A21036 MAPK14 inhibitorp38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. 了解更多 -
(±)-Huperzine A
Catalog No. A21003 AChE inhibitor(??)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). 了解更多 -
Firsocostat
Catalog No. A21000 ACC inhibitorFirsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. 了解更多 -
HDAC-IN-5
Catalog No. A20972 -
Chitinase-IN-1
Catalog No. A20949 insect chitinase and N- acetyl hexosaminidase inhibitorChitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20 uM compound concentration's inhibitory percentage are 75%/67% for chitinase/N- acetyl-hexosaminidase respectively. 了解更多 -
ITI214 free base
Catalog No. A21947 picomolar PDE1 inhibitorITI-214 (free base) is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). 了解更多 -
Kelatorphan
Catalog No. A21884 enkephalin degrading enzymes inhibitorKelatorphan is a full inhibitor of enkephalin degrading enzymes. 了解更多 -
CP-640186 hydrochloride
Catalog No. A21808 ACC inhibitorCP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. 了解更多 -
Nevanimibe hydrochloride
Catalog No. A21767 ACAT1 inhibitorNevanimibe hydrochloride (PD-132301 hydrochloride; ATR101 hydrochloride) is a selective and potent acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. 了解更多 -
BAY 73-6691 racemate
Catalog No. A21745 PDE9 inhibitorBAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1. 了解更多 -
GSK2807 Trifluoroacetate
Catalog No. A21731 SMYD3 inhibitorGSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM. 了解更多 -
(Rac)-Antineoplaston A10
Catalog No. A21689 Ras inhibitor(rac)-Antineoplaston A10 is the racemate of Antineoplaston A10. Antineoplaston A10 is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. 了解更多 -
nor-NOHA acetate
Catalog No. A21673 Arginase inhibitornor-NOHA acetate is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. 了解更多 -
Nanatinostat
Catalog No. A21625 HDAC inhibitorNanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM. 了解更多 -
INCB054329 Racemate
Catalog No. A21609 -
(±)-BAY-1251152
Catalog No. A21564 PTEF/CDK9 inhibitor(±)-BAY-1251152 is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. 了解更多 -
Finasteride acetate
Catalog No. A21537 testosterone 5-alpha-reductase inhibitorFinasteride (acetate) is an orally active testosterone 5-alpha-reductase inhibitor. 了解更多 -
Litronesib Racemate
Catalog No. A21498 kinesin Eg5 inhibitorLitronesib (Racemate) is the racemate of litronesib. Litronesib is a selective, allosteric inhibitor of kinesin Eg5. 了解更多 -
PF-05175157
Catalog No. A21460 ACC inhibitorPF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. 了解更多 -
Sch-42495 racemate
Catalog No. A21408 NEP inhibitorSch-42495 racemate is the racemate of Sch-42495. Sch-42495 is a novel neutral metalloendopeptidase (NEP) inhibitor. Sch-42495 is the orally active ethylester prodrug of SCH 42354. 了解更多 -
(Rac)-Nedisertib
Catalog No. A21383 DNA-PK inhibitor(Rac)-Nedisertib ((Rac)-M3814) is a racemate of Nedisertib, a potent DNA-PK inhibitor, with an IC50 of <3 nM. 了解更多 -
DHMEQ racemate
Catalog No. A21379 NF-κB inhibitorDHMEQ racemate is a NF-κB inhibitor. DHMEQ racemate is less active than (-)-DHMEQ. 了解更多 -
(Rac)-PT2399
Catalog No. A21376 HIF-2α inhibitor(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM. 了解更多 -
Raphin1 acetate
Catalog No. A21373 PPP1R15B inhibitorRaphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). 了解更多 -
AZD-5991 S-enantiomer
Catalog No. A21361 Mcl-1 inhibitorAZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay. 了解更多 -
AZD-5991 Racemate
Catalog No. A21357 Mcl-1 inhibitorAZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is a Mcl-1 inhibitor with an IC50 of <3 nM in FRET assay. 了解更多 -
Rasagiline 13C3 mesylate racemic
Catalog No. A21350 Monoamine oxidase inhibitorRasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. 了解更多 -
β-Secretase Inhibitor IV
Catalog No. A21346 BACE-1 inhibitorβ-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. 了解更多 -
Gepotidacin
Catalog No. A21086 topoisomerase II inhibitorGepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. 了解更多 -
Relebactam
Catalog No. A21071 diazabicyclooctane inhibitorRelebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes. 了解更多 -
Chitinase-IN-2
Catalog No. A20946 insect chitinase and N- acetyl hexosaminidase inhibitorChitinase-IN-2 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 μM/20 μM compound concentration's inhibitory percentage are 98%/92% for chitinase/N- acetyl-hexosaminidase respectively. 了解更多 -
CAL-130 Racemate
Catalog No. A20942 PI3Kδ inhibitorCAL-130 Racemate is the racemate of CAL-130. CAL-130 Racemate is a PI3Kδ inhibitor. 了解更多 -
Acebilustat
Catalog No. A20867 leukotriene A4 hydrolase inhibitorAcebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory drug. 了解更多 -
Lapaquistat acetate
Catalog No. A20851 squalene synthase inhibitorLapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene. 了解更多 -
Olumacostat glasaretil
Catalog No. A20840 ACC inhibitorOlumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). 了解更多 -
Ibrutinib Racemate
Catalog No. A18022 Btk inhibitorIbrutinib Racemate (PCI-32765 Racemate) is the racemate of Ibrutinib. Ibrutinib is a selective, irreversible Btk inhibitor with IC50 value of 0.5 nM. 了解更多 -
HDACs/mTOR Inhibitor 1
Catalog No. A13462 HDACs/mTOR Inhibitor 1HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies. 了解更多 -
Histone Acetyltransferase Inhibitor II
Catalog No. A12331 cell permeable p300 inhibitorHistone Acetyltransferase Inhibitor II is a potent and cell permeable p300 inhibitor, with an IC50 of 5 ?M; Histone Acetyltransferase Inhibitor II can be used in cancer research. 了解更多 -
BACE1-IN-1
Catalog No. A12183 BACE1 inhibitorBACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. 了解更多 -
GNE-140 racemate
Catalog No. A12274 LDHA inhibitorGNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. (R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor. 了解更多 -
Lanabecestat
Catalog No. A12282 BACE1 inhibitorLanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. 了解更多 -
GGTI298 Trifluoroacetate
Catalog No. A16560 GGTase I inhibitorGGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM. 了解更多
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