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￥ 0.00 “MK 1775”的搜索结果
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KN-92 hydrochloride
Catalog No. A15138 -
KN-92 phosphate
Catalog No. A15139 CaMKII 抑制剂KN-92 phosphate是KN-93的非活性衍生物。KN-93是Ca2+/钙调蛋白依赖性激酶II（CaMKII）的选择性抑制剂，竞争性阻断CaM与激酶的结合（Ki = 370 nM）。 了解更多 -
MK-0591 (Quiflapon)
Catalog No. A15163 FLAP 抑制剂MK-0591 (Quiflapon)是一种选择性的特异性5-脂氧合酶激活蛋白（FLAP）抑制剂，在FLAP结合测定中的IC50值为1.6 nM。 了解更多 -
MK-5172 hydrate
Catalog No. A15166 -
MK-5172 potassium salt
Catalog No. A15167 -
MK-5172 sodium salt
Catalog No. A15168 -
MK-8245 Trifluoroacetate
Catalog No. A15170 Liver-targeting SCD 抑制剂?MK-8245 Trifluoroacetate是硬脂酰辅酶A去饱和酶（SCD）的肝靶向抑制剂，对人SCD1的IC50为1 nM，对大鼠SCD1和小鼠SCD1的IC50为3 nM，具有抗糖尿病和抗血脂异常的功效。 了解更多 -
Etoricoxib
Catalog No. A13770 COX-2 抑制剂Etoricoxib特异性结合并抑制环氧合酶2（COX-2），从而抑制花生四烯酸向前列腺素的转化。抑制COX-2可以诱导细胞凋亡并抑制肿瘤细胞的增殖和血管生成。 了解更多 -
PF-3644022
Catalog No. A11282 -
Vaniprevir
Catalog No. A11600 -
Z-VEID-FMK
Catalog No. A12611 Caspase-6 抑制剂Z-VEID-FMK是caspase-6 / Mch2的特异性识别序列。 Z-VEID-FMK是不可逆地抑制VEID依赖性胱天蛋白酶（例如caspase-6）活性的合成肽。 抑制剂被设计为甲酯，以促进细胞渗透性。 了解更多 -
Z-VDVAD-FMK
Catalog No. A12637 -
Z-IETD-FMK
Catalog No. A12800 -
Decanoyl-RVKR-CMK
Catalog No. A16027 -
CMPD-1
Catalog No. A16040 -
Verubecestat (MK-8931)
Catalog No. A16113 β-secretase/BACE1 抑制剂Verubecestat (MK-8931)是一种有效的选择性β-分泌酶抑制剂，是BACE1蛋白抑制剂或Beta-site APP裂解酶1抑制剂。 了解更多 -
LX7101
Catalog No. A16211 -
STO-609 acetate
Catalog No. A16345 -
BMS-5
Catalog No. A12839 -
MK-8353 (SCH900353)
Catalog No. A16838 ERK 抑制剂MK-8353 (SCH900353)是一种口服生物利用型，选择性和有效的ERK抑制剂，在体外抑制激活的ERK1和ERK2，IC50值分别为23.0 nM和8.8 nM（IMAP激酶测定），以及未激活的ERK2，具有IC50值 0.5 nM（MEK1-ERK2耦合测定）。 了解更多 -
Elbasvir (MK-8742)
Catalog No. A16855 NS5A 抑制剂Elbasvir (MK-8742)是一种NS5A抑制剂，可预防丙型肝炎病毒RNA复制和病毒体组装。根据基因型，EC50的中值范围为0.2至3600 pmol/L。 了解更多 -
L-(-)-α-Methyldopa (hydrate)
Catalog No. A18111 DOPA decarboxylase inhibitorMethyldopa Sesquihydrate is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. 了解更多 -
PT2977
Catalog No. A18465 -
MK-2 Inhibitor III
Catalog No. A13608 MAPKAP-K2 (MK-2) inhibitorMK-2 Inhibitor III (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC50 of 0.85 nM. 了解更多 -
SDZ-MKS 492
Catalog No. A12283 cyclic nucleotide phosphodiesterase inhibitorSDZ-MKS 492 (MKS 492) is a selective type III isozyme inhibitor of cyclic nucleotide phosphodiesterase, effective in allergic bronchoconstriction and platelet activating factor (PAF) or LTB4-induced inflammatory reactions in animals. 了解更多 -
Simvastatin
Catalog No. A10845 HMG-CoA reductase inhibitorSimvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. 了解更多 -
Niraparib tosylate
Catalog No. A16618 PARP1/PARP2 inhibitorNiraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. 了解更多 -
Grazoprevir
Catalog No. A17303 Hepatitis C virus NS3/4a protease inhibitorGrazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. 了解更多 -
Niraparib hydrochloride
Catalog No. A18018 PARP1 and PARP2 inhibitorNiraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. 了解更多 -
Lisinopril
Catalog No. A21064 angiotensin-converting enzyme inhibitorLisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. 了解更多
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