微信关注
Total item
Cart Subtotal
￥ 0.00 DNA Damage
-
Ametantrone
Catalog No. A12569 topoisomerase II 抑制剂Ametantrone (AM)是一种合成的9,10-蒽二酮，在位置1和4上带有两个（羟乙基氨基）乙基氨基残基，以及其他蒽醌和蒽环类化合物。 了解更多 -
TAS 103 2HCl
Catalog No. A14141 -
Nemorubicin
Catalog No. A14363 Topoisomerase II 抑制剂Nemorubicin是一种抗癌药物，IC50值为0.08 uM。它对抗烷化剂，拓扑异构酶II抑制剂和铂衍生物具有抗性的肿瘤具有活性。它主要通过抑制拓扑异构酶I起作用。 了解更多 -
Voreloxin Hydrochloride
Catalog No. A15280 -
Levofloxacin hydrate
Catalog No. A16167 topoisomerase II IV 抑制剂Levofloxacin hydrate是广谱的第三代氟喹诺酮类抗生素，是具有抗菌活性的氧氟沙星的旋光性L-异构体。 了解更多 -
Clinafloxacin
Catalog No. A16458 DNA gyrase and topoisomerase IV 抑制剂Clinafloxacin是一种氟喹诺酮，可双重抑制肺炎链球菌中的DNA促旋酶和拓扑异构酶IV。 了解更多 -
Pixantrone
Catalog No. A13022 -
Topotecan
Catalog No. A16815 -
MAC glucuronide α-hydroxy lactone-linked SN-38
Catalog No. A18407 Topoisomerase I inhibitorMAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 drug linker. 了解更多 -
Top1 inhibitor 1
Catalog No. A13304 human topoisomerase I (Top1) inhibitorTop1 inhibitor 1 (compound 28) is a potent human topoisomerase I (Top1) inhibitor with an IC50 value of 29 nM. 了解更多 -
Intoplicine
Catalog No. A20104 DNA topoisomerase I/II inhibitorIntoplicine is a DNA topoisomerase I and II inhibitor. 了解更多 -
Zoliflodacin
Catalog No. A22032 DNA gyrase/topoisomerase inhibitorZoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. 了解更多 -
Dexrazoxane
Catalog No. A17714 topoisomerase IIα inhibitorDexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIα. 了解更多 -
GENZ-644282
Catalog No. A13206 -
CL2A-SN-38
Catalog No. A18392 DNA Topoisomerase I inhibitorCL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. 了解更多 -
MAC glucuronide phenol-linked SN-38
Catalog No. A18403 DNA topoisomerase I inhibitorMAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively. 了解更多 -
9-amino-CPT
Catalog No. A12540 Topoisomerase I inhibitor9-Aminocamptothecin is a topoisomerase I inhibitor with potent anticancer activity. 了解更多 -
Amsacrine hydrochloride
Catalog No. A17707 antineoplastic agentAmsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. 了解更多 -
Pirarubicin Hydrochloride
Catalog No. A18037 topoisomerase II inhibitorPirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors. 了解更多 -
Gepotidacin
Catalog No. A21086 topoisomerase II inhibitorGepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. 了解更多 -
Karenitecin
Catalog No. A21156 topoisomerase I inhibitorKarenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity. 了解更多 -
Edotecarin
Catalog No. A21233 Topoisomerase I inhibitorEdotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM. 了解更多 -
Exatecan Mesylate
Catalog No. A21515 DNA topoisomerase I inhibitorExatecan Mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. 了解更多 -
Daunorubicin
Catalog No. A21903 topoisomerase II inhibitorDaunorubicin (Daunomycin; RP 13057; Rubidomycin) is a topoisomerase II inhibitor with potent antineoplastic activities. 了解更多 -
Amonafide (AS1413)
Catalog No. A10071 Topoisomerase 抑制剂Amonafide (AS1413)是一种DNA插入剂和拓扑异构酶II抑制剂，是治疗肿瘤疾病的抗肿瘤药物之一。 了解更多 -
Epirubicin
Catalog No. A12409 Topoisomerase 抑制剂Epirubicin是一种细胞可渗透的抗肿瘤抗生素。阿霉素的立体异构体，其心脏毒性降低。表柔比星的抗肿瘤作用是通过靶向和抑制Topo II（拓扑异构酶II）来介导的。 了解更多 -
Beta-Lapachone
Catalog No. A13059 DNA topoisomerase II 抑制剂Beta-Lapachone是一种选择性的DNA拓扑异构酶I抑制剂，对DNA拓扑异构酶II或连接酶没有抑制活性。 了解更多 -
Idarubicin HCl
Catalog No. A10465 Topoisomerase 抑制剂Idarubicin HCl是蒽环类抗生素，是一种比柔红霉素具有更高DNA结合能力和更大细胞毒性的抗白血病药物。 了解更多 -
Irinotecan
Catalog No. A10478 -
Genistin (Genistoside)
Catalog No. A10426 Genistin (Genistoside)是一种异黄酮，存在于许多饮食植物中，如大豆和葛根。显示出刺激体内雌激素依赖性乳腺癌细胞生长。 了解更多 -
ABT 492 meglumine (Delafloxacin meglumine)
Catalog No. A15064 ABT 492 meglumine (Delafloxacin meglumine)对喹诺酮敏感和耐药的革兰氏阳性生物更有力，对环丙沙星家族肠杆菌科的某些成员具有类似于环丙沙星的活性，对喹诺酮敏感，非发酵性，革兰氏阴性生物具有类似的活性。 了解更多 -
(-)-Epigallocatechin gallate
Catalog No. A10005 Antioxidant, antiangiogenic, antitumor agent(-)-Epigallocatechin gallate是一种从绿茶中分离出来的强效抗氧化剂多酚类黄酮。 了解更多 -
Etoposide (VP-16)
Catalog No. A10373 Topoisomerase II 抑制剂Etoposide (VP-16)是通过抑制topoisomerase II活性而抑制DNA合成。 了解更多
FILTER BY:
购物选项
- 分类
-
- HDAC (102)
- PARP (49)
- DNA-PK (14)
- Topoisomerase (75)
- Telomerase (6)
- ATM / ATR (21)
- DNA, RNA Synthesis (54)
- RNA/DNA Polymerase (21)
- DNA alkylator (8)
- Synthases / Synthetases (17)
- MTH1 (3)
- Sirtuins (30)
- IRE1 (2)
- DNA Stain (19)
- 作用机制
-
- Inhibitor (抑制剂) (305)
- Agonist (激动剂) (1)
- Activator (激活剂) (11)
- Degrader (降解剂) (1)
- Substrate (底物) (2)
- 靶点
-
- DNA-PK (1)
- DNMT (1)
- EGFR (1)
- HD1 (2)
- HD2 (1)
- HDAC (21)
- HDAC1 (24)
- HDAC10 (4)
- HDAC11 (4)
- HDAC2 (15)
- HDAC3 (19)
- HDAC4 (6)
- HDAC5 (4)
- HDAC6 (23)
- HDAC7 (2)
- HDAC8 (9)
- HDAC9 (3)
- HER2 (1)
- Mdm2 (1)
- MdmX (1)
- NF-κB (1)
- p110α (2)
- p110β (2)
- p110γ (2)
- p110δ (2)
- p53 (2)
- PARP (13)
- PARP1 (10)
- PARP2 (4)
- PDE5 (1)
- SIRT1 (6)
- SIRT2 (5)
- SIRT3 (1)
- Sirtuin (1)
- Tankyrase-1 (5)
- Tankyrase-2 (8)
ADOOQ 产品质量保证
We promise all products to perform as described.