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产品 51 到 100 共 326个

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  1. TGR-1202 hydrochloride (Umbralisib HCl)

    Catalog No. A16278
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    PI3Kδ 抑制剂
    TGR-1202 hydrochloride是一种口服的下一代PI3Kδ抑制剂,在基于酶和细胞的测定中抑制PI3Kδ活性,IC50和EC50值分别为22.2和24.3 nM。 了解更多
  2. AN3365

    Catalog No. A16329
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    leucyl-tRNA synthetase 抑制剂
    AN3365是一种有效的,选择性的亮氨酰tRNA合成酶抑制剂。 了解更多
  3. Lomerizine dihydrochloride

    Catalog No. A16599
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    L-type 拮抗剂
    Lomerizine dihydrochloride是L型和T型Ca2+通道和TRp5通道的拮抗剂,用于治疗偏头痛和眩晕。 了解更多
  4. ASTX-660

    Catalog No. A16996
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    XIAP 抑制剂
    ASTX660是X染色体连锁的凋亡蛋白抑制剂(XIAP)和细胞IAP 1(cIAP1)的口服生物利用型非拟肽拮抗剂,具有潜在的抗肿瘤和促凋亡活性。1799328-86-1 (free base) 1799328-50-9 (HCl) 1799328-90-7 (mesylate) 1799328-88-3 (sulfate) 了解更多
  5. Pitofenone Hydrochloride

    Catalog No. A17053
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    Antispasmodic Agent
    Pitofenone Hydrochloride是抗痉化合物。它是乙酰胆碱酯酶活性的有效抑制剂。 了解更多
  6. Robenidine Hydrochloride

    Catalog No. A16991
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    Antibiotic
    Robenidine Hydrochloride是一种用于控制球虫病的抗生素,球虫病是一种破坏家禽的原生动物感染。 了解更多
  7. Piperoxan hydrochloride

    Catalog No. A18336
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    α2 adrenoceptor antagonist
    Piperoxan hydrochloride is an α2 adrenoceptor antagonist. 了解更多
  8. Cefepime Dihydrochloride Monohydrate

    Catalog No. A17272
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    Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria. 了解更多
  9. Pargyline hydrochloride

    Catalog No. A17288
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    MAO inhibitor
    Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. 了解更多
  10. AX-024 hydrochloride

    Catalog No. A18332
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    TNF receptor inhibitor
    AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases. 了解更多
  11. Fendiline hydrochloride

    Catalog No. A17575
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    Calcium channel blocker
    Fendiline hydrochloride is a nonselective calcium channel blocker. 了解更多
  12. Lincomycin Hydrochloride Monohydrate

    Catalog No. A17584
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    Antibacterial agent
    Lincomycin hydrochloride is a peptidyl transferase and protein translation inhibitor used to treat bacterial infections. It also inhibits growth of plasmodium. 了解更多
  13. Promazine hydrochloride

    Catalog No. A17638
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    D2DR inhibitor
    Promazine Hydrochloride is a phenothiazine compound and D2DR inhibitor. Promazine Hydrochloride has been employed in studies investigating dopamine-stimulated glycosylation of brain proteins in vitro. It has actions similar to chlorpromazine but with less antipsychotic activity. 了解更多
  14. Rimantadine Hydrochloride

    Catalog No. A17649
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    antiviral drug
    Rimantadine is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection. 了解更多
  15. Moxisylyte hydrochloride

    Catalog No. A17725
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    alpha-adrenergic blocking agent
    Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. 了解更多
  16. Mecamylamine Hydrochloride

    Catalog No. A17884
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    nAChR antagonist
    Mecamylamine hydrochloride is a nAChR antagonist previously used to treat hypertension. It displays a wide variety of activities, including reducing depression-like behaviors in subjects with Tourette's syndrome and improving rates of smoking cessation. 了解更多
  17. Metipranolol hydrochloride

    Catalog No. A18064
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    β-adrenergic receptor antagonist
    Metipranolol (hydrochloride) is a non-selective β-adrenergic receptor (β-AR) antagonist. Formulations containing metipranolol have been used in the treatment of elevated IOP in patients with ocular hypertension or glaucoma. 了解更多
  18. Metoclopramide hydrochloride hydrate

    Catalog No. A18072
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    Dopamine D2 antagonist
    Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. 了解更多
  19. Piperidolate hydrochloride

    Catalog No. A18144
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    antimuscarinic
    Piperidolate hydrochloride is an antimuscarinic, Also a potential inhibitor of human glutathione transferase P1-1. 了解更多
  20. Benfluorex hydrochloride

    Catalog No. A18152
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    HNF4α) activator
    Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator. 了解更多
  21. Heptaminol hydrochloride

    Catalog No. A18165
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    Heptaminol hydrochloride is an amino alcohol used as a myocardial stimulant, vasodilator, and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension. 了解更多
  22. Efonidipine hydrochloride

    Catalog No. A21431
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    dual T-type and L-type calcium channel blocker
    Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB). 了解更多
  23. 5-Hydroxy Propafenone D5 Hydrochloride

    Catalog No. A21604
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    5-Hydroxy Propafenone D5 Hcl is the deuterium labeled 5-Hydroxy Propafenone. 了解更多
  24. MK-8033 hydrochloride

    Catalog No. A22011
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    dual c-Met/Ron inhibitor
    MK8033 Hcl is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer. 了解更多
  25. CRT0066101 free base

    Catalog No. A22539
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    PRKDs inhibitor
    CRT0066101 is a PRKDs inhibitor. CRT0066101 suppressed the proliferation and migration of four bladder cancer cell lines in vitro. CRT0066101 blocked tumor growth in a mouse flank xenograft model of bladder cancer. 了解更多
  26. LDN-193189 2HCl

    Catalog No. A22307
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    BMP signaling inhibitor
    LDN193189 HCl (DM-3189) is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β. 了解更多
  27. Cetraxate Hydrochloride

    Catalog No. A22155
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    mucosal protective agent and an anti-ulcer drug
    Cetraxate (DV-1006) Hydrochloride (HCl) is a mucosal protective agent and an anti-ulcer drug candidate. Cetraxate raises levels of calcitonin gene-related peptide and substance P in human plasma. 了解更多
  28. PD153035 (HCl salt)

    Catalog No. A10702
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    EGFR 抑制剂
    PD153035 (HCl salt)是EGFR酪氨酸激酶活性的极其有效和特异的抑制剂。 了解更多
  29. Benazepril HCl

    Catalog No. A10123
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    RAAS 抑制剂
    Benazepril hydrochloride是一种非肽血管紧张素转化酶(ACE)抑制剂。降低自发性高血压大鼠的血压和心肌肥大。 了解更多
  30. Bendamustine HCl (SDX-105)

    Catalog No. A10124
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    Bendamustine Hydrochloride (SDX-105)是一种小分子双功能DNA烷基化剂,结合了氮芥菜碱功能和嘌呤类似物结构。苯达莫司汀具有致密的破坏DNA的功能,使其与用作抗增殖剂的其他化合物区分开来,这些功能被认为可通过多种不同途径(包括凋亡和有丝分裂灾难)促进细胞死亡。 了解更多
  31. Berberine HCl

    Catalog No. A10126
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    Berberine hydrochloride被发现具有对心血管系统的多种有益作用和显着的抗炎活性。 小ber碱可有效降低LPS刺激的巨噬细胞的细胞内超氧化物水平。 小碱对细胞氧化还原的这种恢复是通过其对gp91phox表达的选择性抑制和SOD活性的增强而介导的。 了解更多
  32. Nepicastat HCl

    Catalog No. A11172
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    DBH 抑制剂
    Nepicastat HCl是多巴胺β-羟化酶的抑制剂,该酶催化多巴胺向去甲肾上腺素的转化。 了解更多
  33. Evista (Raloxifene HCl)

    Catalog No. A10375
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    Evista (Raloxifene HCl)是一种口服选择性雌激素受体调节剂(SERM),对骨骼具有雌激素作用,对子宫和乳房具有抗雌激素作用。 了解更多
  34. MK 3207 HCl

    Catalog No. A10598
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    CGRP Receptor 拮抗剂
    MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂,IC50为0.12 nM。 了解更多
  35. IPI-504 (Retaspimycin HCl)

    Catalog No. A11269
    Hsp90 抑制剂
    IPI-504 (Retaspimycin HCl)是新型的,有效的热休克蛋白90(Hsp90)抑制剂。 了解更多
  36. Amorolfine HCl

    Catalog No. A10072
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    Antifungal compound
    Amorolfine hydrochloride是一种吗啉类抗真菌药,可抑制D14还原酶和D7-D8异构酶,这些酶消耗麦角固醇并导致木质甾醇在真菌细胞质细胞膜中积聚。 了解更多
  37. Benserazide HCl (Serazide)

    Catalog No. A10125
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    Benserazide hydrochloride (Serazide)是L-芳族氨基酸脱羧酶的抑制剂。 了解更多
  38. Bupivacaine HCl

    Catalog No. A10168
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    Bupivacaine HCl与化学相关的局部麻醉药相比,Bupivacaine HCl是一种更有效的cAMP抑制剂,较不易产生心血管毒性。 了解更多
  39. Trazodone HCl

    Catalog No. A11703
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    Trazodone HCl 是一种抗抑郁药,属于5-羟色胺受体拮抗剂和再摄取抑制剂。 了解更多
  40. Moxonidine Hydrochloride

    Catalog No. A13416
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    imidazoline receptor 1 激动剂
    Moxonidine Hydrochloride (BDF5895)是咪唑啉1型受体(I1-R)选择性激动剂,为降压剂。 了解更多
  41. CBiPES HCl

    Catalog No. A15811
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    mGlu2 receptor modulator
    CBiPES HCl是mGluR-2的选择性正变构调节剂,IC50值为98.2 nM。 了解更多
  42. Doxycycline HCl

    Catalog No. A10745
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    Doxycycline Hydrochloride是具有类似抗菌活性的合成四环素衍生物。 了解更多
  43. Hexaminolevulinate HCl

    Catalog No. A15966
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    Hexaminolevulinate HCl是具有光动力学性质的5-氨基乙酰丙酸(ALA)的己酯。 了解更多
  44. Cysteamine HCl

    Catalog No. A16474
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    Cysteamine HCl是用于治疗肾病性胱氨酸病的药物和抗氧化剂。 了解更多
  45. Ciprofloxacin HCl

    Catalog No. A16969
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    Ciprofloxacin hydrochloride是一种广谱抗菌剂羧基氟喹啉,一种广泛用作抗菌剂和免疫调节剂的氟喹诺酮类抗生素。 了解更多
  46. Procaine HCl

    Catalog No. A17344
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    Procaine hydrochloride is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. 了解更多
  47. Tacrine HCl

    Catalog No. A17374
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    AChE & butyrylcholinesterase inhibitor
    Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). 了解更多
  48. Melitracen hydrochloride

    Catalog No. A17494
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    dopamine D1/2 receptor antagonist
    Melitracen HCl ia potential dopamine D1/2 receptor antagonist used to treat depression. It is often co-administered with flupenthixol as a treatment for trigeminal neuralgia. It does not effect cardiovascular function. 了解更多
  49. Nefazodone hydrochloride

    Catalog No. A17622
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    5-HT2 receptors inhibitor
    Nefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多
  50. Cevimeline hydrochloride

    Catalog No. A18092
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    mAChR agonist
    Cevimeline (Evoxac) Hcl is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors; used in the treatment of dry mouth associated with sjogren's syndrome. 了解更多

产品 51 到 100 共 326个

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