PARP

Catalog No.Inhibitor Name PARPPARP1PARP2PARP3V-PARPTankyrase-1
A10111Olaparib
***
****
*
A10026Veliparib
***
***
A14182Rucaparib
****
A11243Talazoparib
****
A10046AG-14361
***
A10475INO-1001
**
A10019A-966492
****
****
A15215PJ34
***
A12665PJ34 HCl
***
A11026Niraparib
***
****
*
**
**
A12750UPF 1069
*
**
A14309ME0328
*
**
A14371Benzamide
*
A15375NU1025
**
A10164Iniparib
A12393AZD2461
A16344BGP-15
A10045AG-014699 (Rucaparib)
****
A153704-HQN
*
A15371BYK 204165
*
*
A15372BYK 49187
*
*
A15374EB 47
**
A15373DR 2313
*
**

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. A-966492

    Catalog No. A10019
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    PARP1 抑制剂
    A-966492在全细胞试验中显示出对K(i)为1 nM,EC(50)为1 nM的聚(ADP-核糖)聚合酶-1(PARP-1)酶的高效力。 了解更多
  2. Rucaparib

    Catalog No. A14182
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    PARP-1 抑制剂
    Rucaparib是纯化的全长人PARP-1的有效抑制剂,对LoVo和SW620细胞中的细胞PARP具有更高的抑制作用。 了解更多
  3. MK-4827 (Niraparib)

    Catalog No. A11026
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    PARP 抑制剂
    MK-4827 (Niraparib)是一种新型有效的口服生物可利用的PARP-1和PARP-2抑制剂。 了解更多
  4. BSI-201 (Iniparib)

    Catalog No. A10164
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    PARP 抑制剂
    BSI-201 (Iniparib)是一种有效的PARP-1抑制剂,已被证明可以穿越血脑屏障。 了解更多
  5. Benzamide

    Catalog No. A14371
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    PARP-1 抑制剂
    Benzamide是苯甲酸的酰胺衍生物,是聚(ADP-核糖)聚合酶-1(PARP-1)的抑制剂。 了解更多
  6. UPF 1069

    Catalog No. A12750
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    PARP2 抑制剂
    UPF 1069是一种选择性聚(ADP-核糖)聚合酶(PARP)2抑制剂(PARP-2和PARP-1的IC50值分别为0.3和8.0μM)。 了解更多
  7. BYK 204165

    Catalog No. A15371
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    PARP-1 抑制剂
    BYK204165是一种可渗透细胞的异喹啉二酮化合物,可有效并选择性地抑制聚(ADP-核糖)聚合酶1(PARP1)。 了解更多
  8. EB 47

    Catalog No. A15374
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    PARP1 抑制剂
    EB 47是PARP1的有效抑制剂,IC50为45 nM。 了解更多
  9. BYK 49187

    Catalog No. A15372
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    PARP-1/PARP-2 抑制剂
    BYK 49187,PARP-1和PARP-2抑制剂(无细胞重组PARP-1和鼠PARP-2的pIC50值分别为8.36和7.50)。 了解更多
  10. DR 2313

    Catalog No. A15373
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    PARP 抑制剂
    DR 2313是一种水溶性嘧啶酮化合物,起PARP(聚(ADP-核糖)聚合酶)抑制剂的作用。 了解更多

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