PARP
Catalog No. | Inhibitor Name | PARP | PARP1 | PARP2 | PARP3 | V-PARP | Tankyrase-1 |
---|---|---|---|---|---|---|---|
A10111 | Olaparib | *** | **** | * | |||
A10026 | Veliparib | *** | *** | ||||
A14182 | Rucaparib | **** | |||||
A11243 | Talazoparib | **** | |||||
A10046 | AG-14361 | *** | |||||
A10475 | INO-1001 | ** | |||||
A10019 | A-966492 | **** | **** | ||||
A15215 | PJ34 | *** | |||||
A12665 | PJ34 HCl | *** | |||||
A11026 | Niraparib | *** | **** | * | ** | ** | |
A12750 | UPF 1069 | * | ** | ||||
A14309 | ME0328 | * | ** | ||||
A14371 | Benzamide | * | |||||
A15375 | NU1025 | ** | |||||
A10164 | Iniparib | ||||||
A12393 | AZD2461 | ||||||
A16344 | BGP-15 | ||||||
A10045 | AG-014699 (Rucaparib) | **** | |||||
A15370 | 4-HQN | * | |||||
A15371 | BYK 204165 | * | * | ||||
A15372 | BYK 49187 | * | * | ||||
A15374 | EB 47 | ** | |||||
A15373 | DR 2313 | * | ** |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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MK-4827 (Niraparib)
Catalog No. A11026 PARP 抑制剂MK-4827 (Niraparib)是一种新型有效的口服生物可利用的PARP-1和PARP-2抑制剂。 了解更多 -
BSI-201 (Iniparib)
Catalog No. A10164 PARP 抑制剂BSI-201 (Iniparib)是一种有效的PARP-1抑制剂,已被证明可以穿越血脑屏障。 了解更多 -
Benzamide
Catalog No. A14371 -
BYK 204165
Catalog No. A15371 -
DR 2313
Catalog No. A15373