PARP

Inhibitory Selectivity

Catalog No.	Inhibitor Name	PARP	PARP1	PARP2	PARP3	V-PARP	Tankyrase-1
A10111	Olaparib		***	****			*
A10026	Veliparib		***	***
A14182	Rucaparib	****
A11243	Talazoparib	****
A10046	AG-14361		***
A10475	INO-1001	**
A10019	A-966492		****	****
A15215	PJ34	***
A12665	PJ34 HCl	***
A11026	Niraparib		***	****	*	**	**
A12750	UPF 1069		*	**
A14309	ME0328		*		**
A14371	Benzamide	*
A15375	NU1025	**
A10164	Iniparib
A12393	AZD2461
A16344	BGP-15
A10045	AG-014699 (Rucaparib)	****
A15370	4-HQN	*
A15371	BYK 204165		*	*
A15372	BYK 49187		*	*
A15374	EB 47		**
A15373	DR 2313		*	**

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.