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Resminostat hydrochloride
Catalog No. A15220 HDAC 抑制剂Resminostat hydrochloride是HDAC1/3/6的有效抑制剂（IC50 = 43-72 nM）；对HDAC8的效力较低，IC50为877 nM。 了解更多 -
Dexrazoxane
Catalog No. A17714 topoisomerase IIα inhibitorDexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIα. 了解更多 -
Zoliflodacin
Catalog No. A22032 DNA gyrase/topoisomerase inhibitorZoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. 了解更多 -
Tefinostat
Catalog No. A20258 pan HDAC inhibitorTefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity. 了解更多 -
Intoplicine
Catalog No. A20104 DNA topoisomerase I/II inhibitorIntoplicine is a DNA topoisomerase I and II inhibitor. 了解更多 -
Daunorubicin
Catalog No. A21903 topoisomerase II inhibitorDaunorubicin (Daunomycin; RP 13057; Rubidomycin) is a topoisomerase II inhibitor with potent antineoplastic activities. 了解更多 -
Dehydroaltenusin
Catalog No. A21804 eukaryotic DNA polymerase α inhibitorDehydroaltenusin is a small molecule selective inhibitor of eukaryotic DNA polymerase α, a type of antibiotic produced by a fungus with an IC50 value of 0.68 μM. 了解更多 -
Exatecan Mesylate
Catalog No. A21515 DNA topoisomerase I inhibitorExatecan Mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. 了解更多 -
Edotecarin
Catalog No. A21233 Topoisomerase I inhibitorEdotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM. 了解更多 -
Karenitecin
Catalog No. A21156 topoisomerase I inhibitorKarenitecin (Cositecan) is a topoisomerase I inhibitor, with potent anti-cancer activity. 了解更多 -
Gepotidacin
Catalog No. A21086 topoisomerase II inhibitorGepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. 了解更多 -
Pirarubicin Hydrochloride
Catalog No. A18037 topoisomerase II inhibitorPirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors. 了解更多 -
Amsacrine hydrochloride
Catalog No. A17707 antineoplastic agentAmsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. 了解更多 -
9-amino-CPT
Catalog No. A12540 Topoisomerase I inhibitor9-Aminocamptothecin is a topoisomerase I inhibitor with potent anticancer activity. 了解更多 -
Top1 inhibitor 1
Catalog No. A13304 human topoisomerase I (Top1) inhibitorTop1 inhibitor 1 (compound 28) is a potent human topoisomerase I (Top1) inhibitor with an IC50 value of 29 nM. 了解更多 -
MAC glucuronide phenol-linked SN-38
Catalog No. A18403 DNA topoisomerase I inhibitorMAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively. 了解更多 -
MAC glucuronide α-hydroxy lactone-linked SN-38
Catalog No. A18407 Topoisomerase I inhibitorMAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 drug linker. 了解更多 -
CL2A-SN-38
Catalog No. A18392 DNA Topoisomerase I inhibitorCL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. 了解更多 -
DNA31
Catalog No. A18466 -
Pseudouridimycin
Catalog No. A18520 RNA polymerase 抑制剂Pseudouridimycin (PUM), an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria. 了解更多 -
ACX-362E
Catalog No. A18560 DNA polymerase IIIC 抑制剂ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections, with a MIC50 of 2 μg/mL for C. difficile. ACX-362E displays very potent in vitro and in vivo activities against broad spectrum of C. difficile pathogens. 了解更多 -
Topotecan
Catalog No. A16815 -
Pixantrone
Catalog No. A13022 -
Clinafloxacin
Catalog No. A16458 DNA gyrase and topoisomerase IV 抑制剂Clinafloxacin是一种氟喹诺酮，可双重抑制肺炎链球菌中的DNA促旋酶和拓扑异构酶IV。 了解更多 -
Levofloxacin hydrate
Catalog No. A16167 topoisomerase II IV 抑制剂Levofloxacin hydrate是广谱的第三代氟喹诺酮类抗生素，是具有抗菌活性的氧氟沙星的旋光性L-异构体。 了解更多 -
NVP-TNKS656
Catalog No. A15786 -
Thiolutin
Catalog No. A15386 -
Mithramycin A
Catalog No. A15385 DNA/RNA polymerase 抑制剂Mithramycin A是一种抗生素DNA/RNA聚合酶和可与DNA结合的转录抑制剂，可促进TNF-α的表达。Fas-配体诱导细胞凋亡。 了解更多 -
Oncrasin 1
Catalog No. A15333
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